Journals / Gülhane Tıp Dergisi / 2005 / Cilt: 47 - Sayı: 2

Routine hematologic-radiologic findings at the start treatment and the time period needed to obtain a negative smear in active lung tuberculosis

Aktif akciğer tüberkülozunda tedavi başlangıcındaki rutin hematolojik-radyolojik bulgular ve yayma negatifleşme süresi

Pages
110–113
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

In conclusion, radiologic severity of lesions at the beginning of the treatment may affect the time period to obtain a negative smear.

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Objective & Hypothesis:Routine hematologic-radiologic findings at the start of treatment and the time period needed to obtain a negative smear in active lung tuberculosis This study was designed to investigate the relationships between routine hematologic and radiologic tests and time period to obtain negative smears in patients with smear-positive lung tuberculosis.
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Key Findings & Data:The study involved either sputum or fasting gastric juice smear-positive 216 cases.
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Conclusion & Impact:In conclusion, radiologic severity of lesions at the beginning of the treatment may affect the time period to obtain a negative smear.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Kan hücresi sayımı · Tüberküloz · pulmoner

Abstract

Routine hematologic-radiologic findings at the start of treatment and the time period needed to obtain a negative smear in active lung tuberculosis This study was designed to investigate the relationships between routine hematologic and radiologic tests and time period to obtain negative smears in patients with smear-positive lung tuberculosis. The study involved either sputum or fasting gastric juice smear-positive 216 cases. Complete blood count, tuberculine skin test, postero-anterior chest radiography and smear bacillus load at the start of the study and time period to obtain a negative smear were recorded in all cases. The mean time period to obtain a negative smear was 4.5±1.7 (range: 2-11) weeks. There was a statistically significant relationship between the radiologic severity of lesions and time period to obtain a negative smear (p=0.016). There were no statistically significant relationships between the time period to obtain a negative smear and other clinical and laboratory parameters and tuberculine skin test. The time period to obtain a negative smear was longer than eight weeks in 13 patients. In conclusion, radiologic severity of lesions at the beginning of the treatment may affect the time period to obtain a negative smear. Thus, it should be considered that time period to obtain a negative smear may increase in the absence of drug resistance in patients with tuberculosis who have severe radiologic lesions at the start of treatment.

Özet

Bu çalışma, yayma pozitif akciğer tüberkülozlu hastalarda tedavi başlangıcında yapılan rutin tam kan sayımı ve radyolojik tetkikler ite yaymatanmn negatifleşme süresi arasındaki ilişkileri incelemek amacıyla planlandı. Çalışmaya, balgam veya açlık mide suyu yayma pozitif 216 olgu alındı. Hastaların tedavi başlangıcındaki tam kan sayımı, tüberkülin cilt testi, pos-tero-anterior akciğer grafisi, yayma basil yükü ile yayma negatifleşme süreleri (hafta olarak) kaydedildi. Yayma negatifleşme süresi, ortalama 4.5+1.7 (aralık: 2-11) hafta olarak bulundu. Radyolojik olarak lezyonların yaygınlığı ite yayma negatifleşme süresi arasında istatistiksel olarak anlamlı bir ilişki saptandı (p=0.016). Diğer klinik, laboratuvar parametreler ve tüberkülin cilt testi ile yayma negatifleşme süresi arasında anlamlı ilişki bulunamadı. Yayma negatifleşme süresi, 13 hastada sekiz haftadan daha uzundu. Sonuç olarak hastanın tedavi başlangıcındaki radyolojik tablosu, yaymanın negatifleşme süresini etkileyebilmektedir. Bu nedenle, hastalığın başlangıcında ileri derecede yaygın radyolojik lezyonları olan akciğer tüberkülozlu hastalarda, ilaç direnci olmasa bile yayma negatifleşme sürelerinin uzayabiteceği göz önünde bulundurulmalıdır.

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Cite This Article

KARTALOĞLU, Z., OKUTAN, O., KUNTER, E., ÇİFTÇİ, F., İLVAN, A., BİLGİÇ, H. (2005). Routine hematologic-radiologic findings at the start treatment and the time period needed to obtain a negative smear in active lung tuberculosis. Gülhane Tıp Dergisi, Cilt: 47 - Sayı: 2, 110–113. https://ajindex.com/articles/225684

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