Journals / Gülhane Tıp Dergisi / 2009 / Cilt: 51 - Sayı: 4

Neurosarcoidosis: Report of a case with pituitary-hypothalamic involvement

Nörosarkoidoz: Hipofiziyer-hipotalamik tutulumlu bir olgu sunumu

Pages
247–250
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We, thus, aimed to present our very rare neurosarcoidosis case with pituitary-hypothalamic involvement, which we detected incidentally during the investigation of vascular headache and to review the diagnosis and treatment of sarcoidosis.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:A 38-year-old female patient admitted to our clinics with headache and itching in whole body.
📊
Key Findings & Data:In cranial magnetic resonance imaging performed for the investigation of headache, hypothalamic mass lesion and leptomeningeal sarcoid foci were detected.
💡
Conclusion & Impact:We, thus, aimed to present our very rare neurosarcoidosis case with pituitary-hypothalamic involvement, which we detected incidentally during the investigation of vascular headache and to review the diagnosis and treatment of sarcoidosis.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

A 38-year-old female patient admitted to our clinics with headache and itching in whole body. In cranial magnetic resonance imaging performed for the investigation of headache, hypothalamic mass lesion and leptomeningeal sarcoid foci were detected. The diagnosis of neurosarcoidosis was made on the basis of clinical and laboratory findings and radiological imaging. Cases with sarcoid foci in the form of hypothalamic mass lesion are very rare in the medical literature. We, thus, aimed to present our very rare neurosarcoidosis case with pituitary-hypothalamic involvement, which we detected incidentally during the investigation of vascular headache and to review the diagnosis and treatment of sarcoidosis.

Özet

Otuz sekiz yaşındaki bayan hasta başağrısı ve tüm vücutta yaygın kaşıntı şikayetleriyle kliniğimize başvurdu. Başağrısı etiyolojisine yönelik tetkikleri sırasında çekilen kraniyal manyetik rezonans görüntülemesinde hipotalamik şüpheli kitle lezyon görünümü ve leptomeningeal sarkoid odakları saptandı. Olguya klinik, laboratuvar bulguları ve radyolojik görüntüleri eşliğinde nörosarkoidoz tanısı konuldu. Hipotalamik kitle lezyonu görünümünde sarkoid odakları olan olgulara literatürde oldukça nadir rastlanmaktadır. Bu nedenle vasküler başağrısı etiyolojisine yönelik yapılan tetkikleri sırasında tesadüfi olarak saptadığımız, hipofiziyer-hipotalamik tutulumu olan, nadir görülen nörosarkoidoz olgusunu sunmayı ve sarkoidoz hastalığının tanı ile tedavi aşamalarını gözden geçirmeyi istedik.

🔖

Cite This Article

BAKAR, E. E., SELÇUKİ, D. (2009). Neurosarcoidosis: Report of a case with pituitary-hypothalamic involvement. Gülhane Tıp Dergisi, Cilt: 51 - Sayı: 4, 247–250. https://ajindex.com/articles/225484

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (16)

  1. Ropper AH, Victor M. Adam’s and Victor’s Principles of Neurology. Emre M (Çeviri ed) 8nci baskı. Ankara: Güneş Kitabevi, 2006: 612-614
  2. Athyal RP, Singh S. Sellar and parasellar neurosarcoidosis: magnetic resonance imaging features. Indian J Radiol Imaging 2002; 12: 487-489
  3. Sharma OP. Neurosarcoidosis: a personal perspective based on the study of 37 patients. Chest 1997; 112: 220-228
  4. Zylberberg F, Meary E, Cerez D, Meder J, Frédy D. MRI aspects of central nervous system sarcoidosis. J Radiol 2001; 82: 623-631
  5. Schelhorn J, Smesny U, Fitzek C, et al. Differential diagnosis of solitary neurosarcoidosis. Nervenarzt 2005; 76: 984-987
  6. Zouaoui A, Maillard JC, Dormont D, Chiras J, Marsault C. MRI in neurosarcoidosis. J Neuroradiol 1992; 19: 271-284
  7. Sato N, Sze G, Kim JH. Cystic pituitary mass in neurosarcoidosis. Am J Neuroradiol 1997; 18: 1182-1185
  8. Loh KC, Green A, Dillon WP Jr, Fitzgerald PA, Weidner N, Tyrrell JB. Diabetes insipidus from sarcoidosis confined to the posterior pituitary. Eur J Endocrinol 1997; 137: 514-519
  9. Baudin B, Beneteau-Burnat B, Vaubourdolle M. Angiotensin I- converting enzyme in cerebrospinal fluid and neurosarcoidosis. Ann Biol Clin 2005; 63: 475-480
  10. Maeda K, Kita Y, Uehara S, et al. A case of isolated CNS sarcoidosis with diffuse confluent high intensity lesions at bilateral deep white matter. No To Shinkei 2006; 58: 605-610
  11. Sakuta M, Kumamoto T, Iizuka T, Nishiyama K, Oritsu M. Diagnostic criteria of neurosarcoidosis. No To Shinkei 2006; 58: 471-476
  12. Costabel U, Zaiss A, Wagner DJ, et al. Value of BAL lymphocyte subpopulations for the diagnosis of sarcoidosis. In: Grassi C, Rizzatu C, Pozzi G (eds). Sarcoidosis and Other Granulomatous Disorders. Amsterdam: The Netherlands Elsevier, 1988: 429-432
  13. Dumas JL, Valeyre D, Chapelon-Abric C, et al. Central nervous system sarcoidosis: follow-up at MR imaging during steroid therapy. Radiology 2000; 214: 411-420
  14. Ferriby D, de Seze J, Stojkovic T, et al. Clinical manifestations and therapeutic approach in neurosarcoidosis. Rev Neurol 2000; 156: 965-975
  15. Kang S, Suh JH. Radiation therapy for neurosarcoidosis: report of three cases from a single institution. Radiat Oncol Investig 1999; 7: 309-312
  16. Karouache A, Mounach J, Aziz N, et al. A report of 9 cases of neurosarcoidosis. Rev Neurol 2005; 161: 1091-1101.