Journals / Gülhane Tıp Dergisi / 2010 / Cilt: 52 - Sayı: 4

Konjonktival tümörlerin klinik ve histopatolojik analizi

Clinical and histopathological analysis of conjunctival tumors

Pages
248–251
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Although squamous cell carcinoma is a rare conjunctival malignant tumor, it may be encountered in young age population.

📌 3 Key Takeaways

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Objective & Hypothesis:The aim of our study was to analyze the clinicopathologic features of conjunctival tumors followed at a tertiary care hospital in Turkey.
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Key Findings & Data:One hundred and sixty four patients with surgically excised conjunctival tumors followed between March 1995 and March 2010 were retrospectively reviewed.
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Conclusion & Impact:Although squamous cell carcinoma is a rare conjunctival malignant tumor, it may be encountered in young age population.
🔬Design:Review & Systematic Survey
📍Scope:2010 Verileri
⚙️Variables:Domain Parameters

Abstract

The aim of our study was to analyze the clinicopathologic features of conjunctival tumors followed at a tertiary care hospital in Turkey. One hundred and sixty four patients with surgically excised conjunctival tumors followed between March 1995 and March 2010 were retrospectively reviewed. Clinical data were collected from medical records. Age and gender of patients, and clinical and histopathologic findings of lesions were identified. Of all the patients 139 (84.75%) were male and 25 (15.24%) were female. The mean age of the patients was 26.4 years (range 4 to 65 years). Of the 164 conjunctival lesions, 115 (70.12%) were nevus, 12 (7.31%) were chronic inflammation, 9 (5.48%) were pyogenic granuloma, 6 (3.65%) were limbal dermoid, 5 (3.04%) were racial melanosis, 4 (2.43%) were benign lymphoid hyperplasia, 3 (1.82%) were hemangioma, 2 (1.21%) were primary acquired melanosis, 2 (1.21%) were inflammatory polyp, 2 (1.21%) were squamous cell carcinoma, 1 (0.6%) was malignant melanoma, 1 (0.6%) was squamous papilloma, 1 (0.6%) was keratoacanthoma and 1 (0.6%) was non-Hodgkin lymphoma. In our study, we found that the most common conjunctival benign tumor was nevus. Although squamous cell carcinoma is a rare conjunctival malignant tumor, it may be encountered in young age population.

Özet

Bu çalışmanın amacı Türkiye'de üçüncü basamak bir sağlık merkezinde takip edilen konjonktival tümörlerin klinik ve histopatolojik özelliklerinin değerlendirilmesiydi. Mart 1995 ile Mart 2010 arasında konjonktiva tümörü cerrahi rezeksiyonu uygulanan 164 hasta retrospektif olarak değerlendirildi. Klinik veriler hasta dosyalarından toplanarak elde edildi. Hastaların yaş ve cinsiyetleri ile lezyonun klinik ve histopatolojik özellikleri belirlendi. Çalışmadaki hastalardan 139'u (%84.75) erkek, 25'i (%15.24) kadın idi. Hastaların ortalama yaşı 26.4 (aralık, 4-65) yıl idi. Yüz altmış dört konjonktival lezyondan 115'i (%70.12) nevüs, 12'si (%7.31) kronik inflamasyon, 9'u (%5.48) piyojenik granülom, 6'sı (%3.65) limbal dermoid, 5'i (%3.04) ırksal melanozis, 4'ü (%2.43) benign lenfoid hiperplazi, 3'ü (%1.82) hemanjiyom, 2'si (%1.21) primer kazanılmış melanozis, 2'si (%1.21) inflamatuvar polip, 2'si (%1.21) skuamoz hücreli karsinom, 1'i (%0.6) malign melanom, 1'i (%0.6) hastada skuamoz papillom, 1'i (%0.6) keratoakantoma ve 1'i (%0.6) non-Hodgkin lenfoma olarak belirlendi. Çalışmamızda konjonktivanın en sık gözlenen iyi huylu tümörü nevüs olarak saptanmıştır. Yassı hücreli karsinoma nadir görülen kötü huylu konjonktiva tümörü olmakla birlikte, genç yaş grubunda da karşılaşılabilir.

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Cite This Article

CEYLAN, O. M., UYSAL, Y., ERDUMAN, F. C., GÜLTEKİN, K., DURUKAN, A. H., KÖKSAL, S., MUTLU, F. M., ÖZGE, G. (2010). Konjonktival tümörlerin klinik ve histopatolojik analizi. Gülhane Tıp Dergisi, Cilt: 52 - Sayı: 4, 248–251. https://ajindex.com/articles/225437

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References (17)

  1. Chi MJ, Baek SH. Clinical analysis of benign eyelid and conjunctival tumors. Ophthalmologica 2006; 220: 43-51
  2. Amoli FA, Heidari AB. Survey of 447 patients with conjunctival neoplastic lesions in Farabi Eye Hospital, Tehran, Iran. Ophthalmic Epidemiol 2006; 13: 275-279
  3. Shields CL, Demirci H, Karatza E, Shields JA. Clinical survey of 1643 melanocytic and nonmelanocytic conjunctival tumors. Ophthalmology 2004; 111: 1747-1754
  4. Shields CL, Fasiuddin AF, Mashayekhi A, Shields JA. Conjunctival nevi: clinical features and natural course in 410 consecutive patients. Arch Ophthalmol 2004; 122: 167-175
  5. Shields CL, Shields JA. Tumors of the conjunctiva and cornea. Surv Ophthalmol 2004; 49: 3-24
  6. Ateenyi-Agaba C, Weiderpass E, Smet A, et al. Epidermodysplasia verruciformis human papillomavirus types and carcinoma of the conjunctiva: A pilot study. Br J Cancer 2004; 90: 1777-1779
  7. Kaimbo Wa Kaimbo D, Parys-Van Ginderdeuren R, Missotten L. Conjunctival squamous cell carcinoma and intraepithelial neoplasia in AIDS patients in Congo Kinshasa. Bull Soc Belge Ophtalmol 1998; 268: 135-141
  8. Yoon YD, Grossniklaus H. Tumors of the cornea and conjunctiva. Curr Opin Ophthalmol 1997; 8: 55-58
  9. Tseng SC, Prabhasawat P, Lee SH. Amniotic membrane transplantation for conjunctival surface reconstruction. Am J Ophthalmol 1997; 124: 765-774
  10. Shields CL, Shields JA, Armstrong T. Management of conjunctival and corneal melanoma with surgical excision, amniotic membrane allograft, and topical chemotherapy. Am J Ophthalmol 2001; 132: 576-578
  11. Shields CL, Naseripour M, Shields JA. Topical mitomycin C for extensive, recurrent conjunctivalcorneal squamous cell carcinoma. Am J Ophthalmol 2002; 133: 601-606
  12. Zaki AA, Farid SF. Management of intraepithelial and invasive neoplasia of the cornea and conjunctiva: a long-term follow up. Cornea 2009; 28: 986-988
  13. Poothullil AM, Colby KA. Topical medical therapies for ocular surface tumors. Semin Ophthalmol 2006; 21: 161-169
  14. Herold TR, Hintschich C. Interferon alpha for the treatment of melanocytic conjunctival lesions. Graefes Arch Clin Exp Ophthalmol 2010; 248: 111-115
  15. Lee GA, Hirst LW. Ocular surface squamous neoplasia. Surv Ophthalmol 1995; 39: 429-450
  16. Brownstein S. Malignant melanoma of the conjunctiva. Cancer Control 2004; 11: 310-316
  17. Folberg R, Jakobiec FA, Bernardino VB, Iwamoto T. Benign conjunctival melanocytic lesions. Clinicopathologic features. Ophthalmology 1989; 96: 436-461.