Journals / Flora İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi / 2002 / Cilt: 7 - Sayı: 1

Risk factors for postoperative mediastinitis after open heart surgery

Açık kalp cerrahisi sonrası gelişen mediastinitlerde risk faktörlerinin değerlendirilmesi

Pages
57–62
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

All patients were treated with extensive debridement and long term parenteral antibiotics.

📌 3 Key Takeaways

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Objective & Hypothesis:At the Cardiac Surgery Department of the Akdeniz University Hospital, between 1993 and 1999, post-operative mediastinitis developed in 20 of 1476 patients who had underwent open-heart surgery; the incidence was found to be 13%.
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Key Findings & Data:The following significant risk factors were identified; as preoperative factors: History of diabetes mellitus, functional class IV, preoperative prolonged (> 3 days) antibiotic use, as postoperative factors: Prolonged stay in the intensivecare unit, prolonged central venous catheterization and reoperation.
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Conclusion & Impact:All patients were treated with extensive debridement and long term parenteral antibiotics.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Görülme sıklığı · Geriyedönük çalışma · Antibiyotikler

Abstract

At the Cardiac Surgery Department of the Akdeniz University Hospital, between 1993 and 1999, post-operative mediastinitis developed in 20 of 1476 patients who had underwent open-heart surgery; the incidence was found to be 13%. These cases were analyzed in a case-control study designed to identify risk factors for postoperative mediastinitis. The following significant risk factors were identified; as preoperative factors: History of diabetes mellitus, functional class IV, preoperative prolonged (> 3 days) antibiotic use, as postoperative factors: Prolonged stay in the intensivecare unit, prolonged central venous catheterization and reoperation. Type and duration of surgery were not significantly associated with postoperative mediastinitis. All patients with post-operative mediastinitis had purulent discharge on surgical wound, and other clinical manifestations were fever, sternal dehiscence and sternal pain. The mortality rate was 20% (4 of 20) among the patients with mediastinitis. All patients were treated with extensive debridement and long term parenteral antibiotics.

Özet

Bu çalışmada, Akdeniz Üniversitesi Tıp Fakültesi Hastanesi Kalp-Damar Cerrahisi Kliniği'nde 1993-1999 yılları arasında, açık kalp cerrahisi uygulanan 1476 hastada gelişen postoperatif mediastinitler retrospektif olarak değerlendirilmiş ve insidans %1.3 olarak bulunmuştur. Çalışma, postoperatif mediastinit gelişen olgularda risk faktörlerini tanımlamak amacıyla olgu-kontrol çalışması şeklinde dizayn edildi. Risk faktörleri pre-operatif, operatif ve postoperatif dönemlere ayrılarak değerlendirildi. Preoperatif faktörlerden; diabetes mel-litus varlığı, fonksiyonel sınıf IV, operasyon öncesi uzun süreli (> 3 gün) antibiyotik kullanımı, postoperatif faktörlerden; yoğun bakımda uzun süreli yatış, uzun süreli santral venöz kateter varlığı ve reoperasyon istatis-tiksel olarak anlamlı oranda mediastinit gelişimine katkıda bulunan risk faktörleri olarak belirlendi. Cerrahi girişimin tipi ve süresi postoperatif mediastinit gelişimiyle ilişkili bulunmadı. Postoperatif mediastinit tanımlanan hastaların hepsinde keşi yerinde pürülan akıntı vardı; ateş, sternal ayrılma ve ağrı diğer bulgulardı. Mediastinit gelişen hastalarda mortalite' %20 olarak saptandı. Hastalar derin cerrahi debridman ve uzun süreli parenteral antibiyotikle tedavi edildi.

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Cite This Article

İNANA, D., SABA, R., GÖLBAŞI, İ., AK, İ., TÜRKAY, C., MAMIKOĞLU, L. (2002). Risk factors for postoperative mediastinitis after open heart surgery. Flora İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi, Cilt: 7 - Sayı: 1, 57–62. https://ajindex.com/articles/224465

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