Journals / Flora İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi / 2018 / Cilt: 23 - Sayı: 3

Varicella Pneumonia in a Healthy Adult: Case Report

Sağlıklı Erişkinde Varisella Pnömonisi: Olgu Sunumu

Pages
154–158
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

As a result; it is once again understood how important vaccination for vaccine-preventable infections is, and care should be taken in terms of viral infections with rash and the complications that may arise therefrom.

📌 3 Key Takeaways

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Objective & Hypothesis:Varicella virus infection is a highly contagious, mild, rash viral disease often seen in childhood.
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Key Findings & Data:A 31-year-old male patient was admitted to the emergency department on the 5th day of onset of rash on hisback and all-body rash and on the development of complaints of high fever, chills, widespread chest pain, drowsiness and coughing during the last 2 days.
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Conclusion & Impact:As a result; it is once again understood how important vaccination for vaccine-preventable infections is, and care should be taken in terms of viral infections with rash and the complications that may arise therefrom.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Varicella virus infection is a highly contagious, mild, rash viral disease often seen in childhood. In adult age, it is more severe and complicated. In adults, the most common life-threatening complication is varicella pneumonia. A 31-year-old male patient was admitted to the emergency department on the 5th day of onset of rash on hisback and all-body rash and on the development of complaints of high fever, chills, widespread chest pain, drowsiness and coughing during the last 2 days. Physical examination revealed tachypnea and there were maculopapular and vesicular lesions on his whole body. He was a smoker and his child had suffered from chickenpox, two weeks earlier. The eyelids were edematous, the conjunctive were hyperemic and the oropharynx and tonsils were normal. Pulmonary auscultation revealed bilateral crackles. On examination, he was febrile (38.5ºC), heart rate was 120 beats/min, arterial blood pressure was 100/60 mmHg and oxygen saturation was 88%. In laboratory examinations; leukocyte count: 7300/μL (49% PNL, 37% lymphocytes, 13% monocytes), platelet count: 83.000/mm3, C-reactive protein: 15.7 mg/L, erythrocyte sedimentation rate: 13 mm/hour, blood sugar: 91 mg/dL, urea: 26 mg/dL, creatinine: 0.6 mg/dL, ALT: 112 U/L, AST: 151 U/L, ALP: 244 U/L, GGT: 414 U/L, LDH: 4400 U/L, and HBsAg, anti-HBs, anti-HCV and anti-HIV were negative. A diffuse, poorly defined, bilateral alveolar-interstitial opacities were detected on her chest X-ray. Treatment with ampicillin-sulbactam (1 g IV 4 times a day) + acyclovir (3 x 10 mg/kg/day IV) was initiated empirically with varicella pneumonia plus seconder bacterial pneumonia. Varicella IgM was positive and Varicella IgG were negative in the patient’s tests. On the 10th day of the patients treatment, he was discharged by cure after he recovery his laboratory and clinical findings. As a result; it is once again understood how important vaccination for vaccine-preventable infections is, and care should be taken in terms of viral infections with rash and the complications that may arise therefrom.

Özet

Varisella virüs infeksiyonu, sıklıkla çocukluk çağında görülen oldukça bulaşıcı, hafif seyirli, döküntülü viral bir hastalıktır. Erişkin çağda geçirildiğinde daha ağır bir tabloya yol açar ve komplikasyonlarla seyreder. Erişkinde yaşamı tehdit eden en sık komplikasyonu varisella pnömonisidir. Otuz bir yaşında erkek hasta, beş gün önce sırttan başlayan ve tüm vücuda yayılan döküntüler ve son iki gündür olan yüksek ateş, üşüme, titreme, batıcı tarzda yaygın göğüs ağrısı, nefes darlığı ve öksürük şikayetlerinin gelişmesi üzerine acil servise başvurdu. Hasta takipneik görünümde idi ve tüm vücudunda makülopapüler ve veziküler lezyonlar vardı. Hastanın sigara kullandığı ve çocuğunun iki hafta önce suçiçeği geçirdiği bilgisi alındı. Göz kapakları ödemli, konjunktivalar hiperemik, orofarenks ve tonsiller olağandı. Her iki akciğerde yaygın ralleri saptandı. Aksiller ateş 38.5°C, nabız taşikardik (120 ritmik/dakika) idi. Arteryel kan basıncı 100/60 mmHg ve oksijen satürasyonu %88 idi. Laboratuvar incelemelerinde; lökosit sayısı: 7300/µL (%49 PNL, %37 lenfosit, %13 monosit), trombosit sayısı: 83.000/mm3, C-reaktif protein: 15.7 mg/L, eritrosit sedimentasyon hızı: 13 mm/saat, kan şekeri: 91 mg/ dL, üre: 26 mg/dL, kreatinin: 0.6 mg/dL, ALT: 112 U/L, AST: 151 U/L, ALP: 244 U/L, GGT: 414 U/L, LDH: 4400 U/L, HBsAg, anti-HBs, anti-HCV ve anti-HIV negatif idi. PA akciğer grafisinde; bilateral, yaygın, nodüler tarzda infiltratif görünüm izlendi. Varisella pnömonisi + sekonder bakteriyel pnömoni ön tanısıyla ampirik olarak ampisilin-sulbaktam (günde dört kez 1 g IV) + asiklovir (3 x 10 mg/kg/ gün IV) tedavileri başlanan hastanın tetkiklerinde Varisella IgM pozitif, Varisella IgG negatif olarak saptandı. Hastanın tedavisinin 10. gününde laboratuvar ve klinik bulguları düzelmesi üzerine şifa ile taburcu edildi. Sonuç olarak, döküntülü viral infeksiyonlar ve bunlara bağlı gelişebilecek komplikasyonlar açısından dikkatli davranılması gerektiği ve aşı ile önlenebilir infeksiyonlar için aşılamanın ne kadar önemli olduğu bir kez daha anlaşılmıştır.

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Cite This Article

ÇEVİKER, S. A., GÜNAL, Ö. (2018). Varicella Pneumonia in a Healthy Adult: Case Report. Flora İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi, Cilt: 23 - Sayı: 3, 154–158. https://ajindex.com/articles/224455

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