Journals / Flora İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi / 1997 / Cilt: 2 - Sayı: 2

Diagnostic value of adenosine deaminase level of cerebrospinal fluid in tuberculous meningitis

Tüberküloz menenjitte beyin omurilik sıvısı adenozin deaminaz düzeyinin tanı değeri

Pages
127–131
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In addition, a statistically sig¬nificant increase in the levels of ADA were found in CSF of patients with tuberculous meningitis compared to the group of bacterial meningitis.

📌 3 Key Takeaways

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Objective & Hypothesis:Adenosine deaminase (ADA) activities were investigeted in the cerebrospinal fluids of 14 patients with tub.erculous meningitis, 20 with bacterial meningitis and 20 control cases without meningitis.
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Key Findings & Data:The highest ADA activities were observed in patients with tuberculous meningitis (mean= 17.95 U/L).
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Conclusion & Impact:In addition, a statistically sig¬nificant increase in the levels of ADA were found in CSF of patients with tuberculous meningitis compared to the group of bacterial meningitis.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Adenosine deaminase (ADA) activities were investigeted in the cerebrospinal fluids of 14 patients with tub.erculous meningitis, 20 with bacterial meningitis and 20 control cases without meningitis. The highest ADA activities were observed in patients with tuberculous meningitis (mean= 17.95 U/L). The mean ADA levels were found as 0.99 U/L in the control cases and 4.31 U/L in patients with bacterial meningitis. A sta¬tistically significant increase in the activity of ADA was found in cerebrospinal fluids (CSF) of patients with tuberculous meningitis and bacterial meningitis-compared to the control groups. In addition, a statistically sig¬nificant increase in the levels of ADA were found in CSF of patients with tuberculous meningitis compared to the group of bacterial meningitis.

Özet

Adenozin deaminaz (ADA) aktivitesi, tüberküloz menenjitli 14, bakteriyel menenjitli 20 ve menenjit bul¬gusu olmayan 20 kontrol olgusunun beyin omurilik sıvılarında çalışıldı. En yüksek ADA aktivitesi tüberküloz menenjitli hastalarda (ort= 17.95 U/L) gözlendi. Ortalama ADA aktiviteleri, kontrollerde 0.99 U/L ve bakte¬riyel menenjitli hastalarda 4.31 U/L olarak bulundu. Tüberküloz ve bakteriyel menenjitli hastalarda beyin omu¬rilik sıvısı (BOS) ADA aktivitesi kontrol grubundakine kıyasla istatistiksel olarak anlamlı derecede yüksek bu¬lundu. Ayrıca tüberküloz menenjitli hastaların ADA değerleri bakteriyel menenjitli hasta grubundakine göre de istatistiksel olarak anlamlı derecede yüksek bulundu.

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Cite This Article

ARIBAŞ, E. T., ÖZCAN, M., AY, M., SÜNBÜL, M., BİTİRGEN, M. (1997). Diagnostic value of adenosine deaminase level of cerebrospinal fluid in tuberculous meningitis. Flora İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi, Cilt: 2 - Sayı: 2, 127–131. https://ajindex.com/articles/224419