Journals / Fırat Tıp Dergisi / 2020 / Cilt: 25 - Sayı: 4

Maternal and Perinatal Outcomes of Pregnancies Complicated with Severe Preeclampsia, Eclampsia and HELLP Syndrome

Ağır Preeklampsi, Eklampsi ve HELLP Sendromu Tanısıyla Komplike Olmuş Gebeliklerin Maternal ve Perinatal Sonuçları

Pages
189–194
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Correct diagnosis and timely intervention can decrease the risk of maternal and perinatal morbidity and mortality.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: The aim of our study is to determine the maternal and perinatal morbidity and mortality rates of patients with severe preeclampsia, eclampsia and HELLP syndrome and to compare them with the literature data.
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Key Findings & Data:Results: During the study period 33719 delivery was occurred in our hospital.
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Conclusion & Impact:Correct diagnosis and timely intervention can decrease the risk of maternal and perinatal morbidity and mortality.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: The aim of our study is to determine the maternal and perinatal morbidity and mortality rates of patients with severe preeclampsia, eclampsia and HELLP syndrome and to compare them with the literature data. Material and Method: The data of the patients who were followed up with the diagnosis of severe preeclampsia, eclampsia and Hellp syndrome for two years and recorded in the electronic data information system were analyzed retrospectively. Results: During the study period 33719 delivery was occurred in our hospital. The preeclampsia, eclampsia and HELLP syndrome rate were found as 1.2% (n =407), 0.12% (n =41) and 0.2% (n =65) respectively. Maternal age, gravidity and parity were found to be higher in the HELLP syndrome group than in the severe preeclampsia and eclampsia groups. Women in the eclampsia group were more likely to deliver by Caesarean section than those in the HELLP syndrome and severe preeclampsia groups (80.5%, 75.4%, 68.8%, respectively) (p =0.005). The rates of adverse maternal outcomes for women in the HELLP syndrome and eclampsia groups were higher than the rates of adverse maternal outcomes in the severe preeclampsia group (13.8%, 12.2%, 4%, respectively) (p <0.0001). Acute renal failure (ARF) was the most common adverse outcome. ARF was most common in the HELLP syndrome group (10.8%). No significant difference in neonatal morbidity and perinatal mortality were found among the three groups. Conclusion: This study demonstrates that pregnancies complicated with HELLP syndrome and eclampsia have a significiantly higher frequency of maternal morbidity than pregnancies with severe preeclampsia. Correct diagnosis and timely intervention can decrease the risk of maternal and perinatal morbidity and mortality.

Özet

Amaç: Araştırmamızın amacı ağır preeklampsi, eklampsi ve HELLP sendromu tanılı hastaların maternal ve perinatal morbidite ve mortalite oranlarının saptanması ve literatür verileriyle karşılaştırılmasıdır. Gereç ve Yöntem: İki yıllık sürede ağır preeklampsi, eklampsi ve Hellp sendromu tanısı ile izlenen ve elektronik veri bilgi sistemine kaydedilen hastaların verileri retrospektif olarak incelendi. Bulgular: Çalışma periyodu boyunca toplam 33719 doğum gerçekleşti. Hastanemizde ağır preeklampsi oranı %1.2 (n =407), Eklampsi oranı %0.12 (n =41), HELLP sendromu oranı %0.2 (n =65) olarak tespit edildi. Çalışmamızda maternal yaş, gravide ve parite HELLP sendromu grubunda, ağır preeklampsi ve eklampsi grubuna göre daha yüksek saptandı. Sezaryen doğum oranı eklampsi grubunda, preeklampsi ve HELLP sendromu grubuna göre daha yüksek saptandı (sırasıyla %80.5, %75.4, %68.8) (p =0.005). Maternal morbidite oranı HELLP sendromu ve eklampsi gruplarında, preeklampsi grubuna göre daha fazla saptandı (sırasıyla %13.8, %12.2, %4) (p <0.0001). Akut böbrek yetmezliği (ABY) en sık maternal morbidite nedeni olarak gözlendi. En sık ABY, HELLP sendromu grubunda saptandı (%10.8). Neonatal morbidite ve perinatal mortalite oranları açısından gruplar arasında anlamlı fark saptanmadı. Sonuç: Bizim çalışmamız maternal morbidite açısından HELLP sendromu ve eklampsinin ağır preeklampsiye göre daha yüksek oranda kötü sonuçlara yol açtığını ortaya koymaktadır. Erken tanı ve zamanında uygun hızlı tedavi ile sonuçları iyileştirmek mümkündür.

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Cite This Article

BAYRAK, M., GÜNGÖRDÜK, K., YILDIRIM, G., TEKİRDAĞ, A. (2020). Maternal and Perinatal Outcomes of Pregnancies Complicated with Severe Preeclampsia, Eclampsia and HELLP Syndrome. Fırat Tıp Dergisi, Cilt: 25 - Sayı: 4, 189–194. https://ajindex.com/articles/223535

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