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Journals / Dokuz Eylül Üniversitesi Tıp Fakültesi Dergisi / 1995 / Cilt: 9 - Sayı: 2

Benign prostat hiperplazisi, prostatik intraepitelyal neoplazi ve adenokarsinomlarda PSA analizi

Gonca Gülten ATAÇ
Kutsal YÖRÜKOĞLU
Fatih KUYUCUOĞLU
Oya GÖRE
Pages
33–38
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Our results suggest that PIN is a preneoplaslic disease and that the tumor differentiation is reflected by the Gleason score.

📌 3 Key Takeaways

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Objective & Hypothesis:Prostate specific antigen (PSA) is an organ specific antigen which is produced by both benign and malignant prostatic epithelial cells.
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Key Findings & Data:Immunoreaclivity of PSA in normal, premalignant and malignant prostate tissue was evaluated in 13 surgical specimens.
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Conclusion & Impact:Our results suggest that PIN is a preneoplaslic disease and that the tumor differentiation is reflected by the Gleason score.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Prostate specific antigen (PSA) is an organ specific antigen which is produced by both benign and malignant prostatic epithelial cells. Immunoreaclivity of PSA in normal, premalignant and malignant prostate tissue was evaluated in 13 surgical specimens. This article focuses on the relationship between PSA and the pathologic entities of prostatic hyperplasia (BPH), prostatic intraepithelial neoplasia (PIN) and prostatic adenocarcinoma. Our results suggest that PIN is a preneoplaslic disease and that the tumor differentiation is reflected by the Gleason score.

Özet

Prostat spesifik antijen (PSA), benign ve malign prostat epitel hücreleri tarafından üretilen organ spesifik bir antijendir. Bu çalışmada 13 cerrahi materyalde premalign ve malign prostat dokularında PSA immünoreaktivitesi değerlendirildi. PSA ile prostat hiperplazisi (BPII), prostatik intraepitelyal neoplazi (PIN) ve prostat adeno-karsinomu arasındaki bağlantılar üzerinde duruldu. Sonuçlarımız, PIN'nın preneoplastik bir hastalık olduğunu ve Gleason skorlamasının tümör diferansiasyommu yansıttığını düşündürdü.

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Cite This Article

ATAÇ, G. G., YÖRÜKOĞLU, K., KUYUCUOĞLU, F., GÖRE, O. (1995). Benign prostat hiperplazisi, prostatik intraepitelyal neoplazi ve adenokarsinomlarda PSA analizi. Dokuz Eylül Üniversitesi Tıp Fakültesi Dergisi, Cilt: 9 - Sayı: 2, 33–38. https://ajindex.com/articles/222456