Journals / Glokom Katarakt / 2012 / Cilt: 7 - Sayı: 3

Comparison of functional and structural tests in patients with primary open angle glaucoma (High tension glaucoma) and ocular hypertension

Primer açık açılı glokom (Yüksek basınçlı glokom) ve oküler hipertansiyon hastalarında fonksiyonel ve yapısal testlerin karşılaştırılması

Pages
141–146
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The correlations between OCT and CST in POAG group were clinically significant.

📌 3 Key Takeaways

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Objective & Hypothesis:Purpose: To investigate the correlation between contrast sensitivity test (CST) and visual field (VF) and optic coherence tomography (OCT) in patients with high tension glaucoma, a subtype of primary open angle glaucoma (POAG) and ocular hypertension (OHT).
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Key Findings & Data:Material and Methods: Forty patients with POAG, 55 patients with OHT, and 40 control subjects were included in this study.
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Conclusion & Impact:The correlations between OCT and CST in POAG group were clinically significant.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Tomografi · optik koherens · Glokom

Abstract

Purpose: To investigate the correlation between contrast sensitivity test (CST) and visual field (VF) and optic coherence tomography (OCT) in patients with high tension glaucoma, a subtype of primary open angle glaucoma (POAG) and ocular hypertension (OHT). Material and Methods: Forty patients with POAG, 55 patients with OHT, and 40 control subjects were included in this study. Full ophthalmological examination, VF Test by using Humprey Perimetry and CST by “Sinewave Contrast Test” were performed. RNFL thicknesses of subjects were scanned with the Cirrus HD-OCT. Results: In POAG group, mean CST score was under normal limits at spatial frequency of 6 cpd and within normal limits but close to the lower limit at 18 cpd. There were differences among groups in CST scores at spatial frequency of 1.5 cpd. A positive correlation between MD and CST score at spatial frequency of 1.5 cpd and a negative correlation between PSD and CST score at spatial frequency at 1.5 and 6 cpd were determined in OHT group. A positive correlation between CST scores at spatial frequency of 1.5 cpd and average RNFL thickness, RNFL thicknesses at temporal and inferior quadrants and in POAG patients. Conclusion: In our study, there was a reduction in CST score at middle spatial frequencies. Significant differences between POAG and control groups and OHT and control groups in CST score at spatial frequency of 1.5 cpd were found. The correlations found between VF and CST were not clinically significant. The correlations between OCT and CST in POAG group were clinically significant.

Özet

Amaç: Primer açık açılı glokomun (PAAG) bir tipi olan yüksek basınçlı glokomlu ve oküler hipertansiyonlu (OHT) hastalarda kontrast duyarlılık (KD) ile bilgisayarlı görme alanı (GA) ve optik koherens tomografi (OKT) testleri arasındaki korelasyonu araştırmak. Gereç ve Yöntemler: Kırk PAAG, 55 OHT hastası ve glokom tanısı olmayan 40 olgu kontrol grubu olarak çalışmaya dahil edildi. Çalışma kapsamındaki tüm olgulara ayrıntılı oftalmolojik muayene, Humprey perimetresi ile 30-2 GA testi ve “Sine Wave Contrast Test” eşeli ile KD ölçümleri yapıldı. Tüm olguların Cirrus HD-OCT ile retina sinir lifi tabakası (RSLT) kalınlığı ölçüldü. Bulgular: PAAG grubunda 6 cpd frekansta KD ortalaması normal sınırların altında, 18 cpd frekansta normal sınırlarda fakat alt sınıra yakın saptandı. Bir buçuk cpd frekansta PAAG grubuyla kontrol grubu arasında ve OHT grubuyla kontrol grubu arasında istatistiksel olarak anlamlı bir farklılık saptandı. OHT grubunda MD ile 1.5 cpd frekanstaki KD değerleri arasında pozitif korelasyon ve PSD ile 1.5 ve 6 cpd frekanslardaki KD değerleri arasında negatif korelasyon saptandı. PAAG hastalarında KD fonksiyonunun 1.5 cpd uzaysal frekansındaki değerleri ile ortalama kalınlık, temporal ve inferiyor kadranlardaki RSLT kalınlıkları arasında ve inferiyor yerleşimli saat kadranlarındaki RSLT kalınlıkları arasında anlamlı pozitif korelasyon saptandı. Sonuç: Çalışmamızda, PAAG grubunda özellikle 6 cpd (orta) uzaysal frekansta KD'da azalma ve sadece 1.5 cpd frekansındaki KD fonksiyonunda PAAG hastalarıyla kontrol grubu arasında ve OHT hastalarıyla kontrol grubu arasında anlamlı farklılık mevcuttu. Glokom hasarını değerlendiren fonksiyonel testler olan GA ve KD testleri arasında saptanan korelasyonlar, klinik olarak anlamlı bulundu. PAAG grubunda OKT ile KD arasındaki korelasyonlar klinik olarak anlamlıydı.

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Cite This Article

ŞAHLI, E., TEKELİ, O. (2012). Comparison of functional and structural tests in patients with primary open angle glaucoma (High tension glaucoma) and ocular hypertension. Glokom Katarakt, Cilt: 7 - Sayı: 3, 141–146. https://ajindex.com/articles/219621

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