Journals / Flora İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi / 2000 / Cilt: 5 - Sayı: 1

Haemophilus influenzae in cystic fibrosis cases: A lower respiratory tract infection agent

Kistik fibrozis olgularında haemophilus influenzae: Bir alt solunum yolu infeksiyonu etkeni

Pages
44–48
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The strains were studied for antibiotic susceptibility by Kirby-Bauer disk diffussion method; for ampicillin, as an empiric therapeutic agent, it was found 75.7%.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:In 288 sputum samples collected from children with cystic fibrosis (CF), Haemophilus influenzae was examined by enriched Columbia agar which is a selective media for routine practice.
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Key Findings & Data:H. influenzae was the most frequent pathogen (11.4%) with 33 strains, the following one was Pseudomonas aeruginosa (11.1%) with 32 strains.
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Conclusion & Impact:The strains were studied for antibiotic susceptibility by Kirby-Bauer disk diffussion method; for ampicillin, as an empiric therapeutic agent, it was found 75.7%.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Kistik fibröz · Haemophilus enfeksiyonları · Haemophilus influenzae

Abstract

In 288 sputum samples collected from children with cystic fibrosis (CF), Haemophilus influenzae was examined by enriched Columbia agar which is a selective media for routine practice. H. influenzae was the most frequent pathogen (11.4%) with 33 strains, the following one was Pseudomonas aeruginosa (11.1%) with 32 strains. After typing procedures, most of the isolates were found as non-typable strains (33.3%) and among the Biotype-I (54.5%). The strains were studied for antibiotic susceptibility by Kirby-Bauer disk diffussion method; for ampicillin, as an empiric therapeutic agent, it was found 75.7%. The susceptibility ratios were 100% for imipenem and 51.5% for cephalotin. In CF cases, H. influenzae as a pathogen affecting the prognosis, seems to be an agent that must be investigated.

Özet

Kistik fibrozis (KF) tanısıyla izlenen çocuklardan alınan 288 balgam örneğinde, rutin kullanıma uygun selektif zenginleştirilmiş Columbia ağar besiyeri kullanılarak Haemophilus influenzae varlığı araştırılmıştır. İncelenen örneklerden 33 suş ile H. influenzae en sık izole edilen (% 11.4) etken olarak saptanırken, Pseudomonas aeruginosa 32 suş ile ikinci sırayı (% 11.1) almaktaydı. Serotiplemesi ve biyotiplemesi yapılan H. influenzae izolatlarının çoğunluğunu tiplendirilemeyen suşlar (%33.3) ve biyotip-l (%54.5) oluşturmaktaydı. Suşların Kirby-Bauer disk diffüzyon yöntemiyle yapılan antibiyotik duyarlılık testleri sonucunda; ampisilin duyarlılığı %75.7 olarak bulunurken, imipenem duyarlılığı %IOO, sefalotin duyarlılığı ise %5I.5 olarak saptandı. KF olgularında prognozu etkileyen bir patojen olarak H. influenzae, araştırılması gereken bir etken olarak görülmektedir.

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Cite This Article

AKTEPE, O. C., ÖZÇELİK, U., ÇÖPLÜ, N., ULUUTKU, S., KİPER, N., GÖÇMEN, A. (2000). Haemophilus influenzae in cystic fibrosis cases: A lower respiratory tract infection agent. Flora İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi, Cilt: 5 - Sayı: 1, 44–48. https://ajindex.com/articles/218333

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