SavedAdd your journal

Journals / Haseki Tıp Bülteni / 2015 / Cilt: 53 - Sayı: 1

A Rare Cause of Abdominal Pain in Children: Hereditary Angioedema

Çocuklarda Karın Ağrısının Nadir Bir Nedeni: Herediter Anjioödem

Deniz ÖZÇEKER
Zeynep TAMAY
Agop ÇITAK
Muhammet BULUT
Nermin GÜLER
Pages
98–100
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Pediatricians and emergency physicians should keep in mind this rare disease in the differential diagnosis of severe abdominal pain.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Hereditary angioedema (HA) is a rare, autosomal-dominant genetic disorder presenting with recurrent attacks of angioedema.
📊
Key Findings & Data:The most commonly involved organs include the extremites, face, neck, upper respiratory tract, genital region and the gastrointestinal tract.
💡
Conclusion & Impact:Pediatricians and emergency physicians should keep in mind this rare disease in the differential diagnosis of severe abdominal pain.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Hereditary angioedema (HA) is a rare, autosomal-dominant genetic disorder presenting with recurrent attacks of angioedema. The most commonly involved organs include the extremites, face, neck, upper respiratory tract, genital region and the gastrointestinal tract. Edema of the intestinal mucosa can cause temporary obstruction and severe abdominal pain that can be confused with acute abdomen. Pediatricians and emergency physicians should keep in mind this rare disease in the differential diagnosis of severe abdominal pain.

Özet

Herediter anjioödem (HA); tekrarlayan anjioödem atakları ile seyreden, nadir görülen otozomal dominant kalıtılan bir hastalıktır. Anjioödem en sık kol ve bacaklarda, yüzde, boyunda, solunum yollarında, genital bölgede ve visseral organlarda görülür. İntestinal mukoza ödemi geçici obstrüksiyona ve akut batın ile karışabilen şiddetli karın ağrılarına neden olabilir. Burada olgu sunuları eşliğinde karın ağrısı ile gelen çocukta bu nadir nedeni çocuk ve acil hekimlerinin hatırlamasını sağlamak amaçlandı.

🔖

Cite This Article

ÖZÇEKER, D., TAMAY, Z., ÇITAK, A., BULUT, M., GÜLER, N. (2015). A Rare Cause of Abdominal Pain in Children: Hereditary Angioedema. Haseki Tıp Bülteni, Cilt: 53 - Sayı: 1, 98–100. https://ajindex.com/articles/218184

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (13)

  1. Agostoni A, Cicardi M. Hereditary and acquired C-1 inhibitor deficiency: biological and clinical characteristics in 235 patients. Medicine 1992;71:206-15
  2. Bork K, Meng G, Staubach P, et al. Hereditary angioedema: new findings concerning symptoms, affected organs, and course. Am J Med 2006;119:267-74
  3. Osler W. Hereditary angio-neurotic oedema. Am J Med Sci 1888;95:362-7.4. Frank MM. Herditary angioedema: a half century of progress. J Allergy Clin Immunol 2004;114:626-8
  4. Fabiani JE, Paulin P, Simkin G, Leoni J, Palombarani S, Squiquera L. Hereditary angioedema: therapeutic effect of danazol on C4 and C1 esterase inhibitors. Ann Allergy 1990;64:388-92
  5. Witschi A, Krahenbühl L, Frei E, Saltzman J, Spath PJ, Müller UR. Colorectal intussusception: An unusual gastrointestinal complication of hereditary angioedema. Int Arch Allergy Immunol 1996;111:96-8
  6. Hermann G, Scheider L, Krieg T, Hunzelmann N, Scharffetter-Kochanek K. Efficacy of danazol treatment with the new variant of hereditary angioedema (HAE III). Br J Dermatol 2004;150:155-7 8. Winnewisser J, Rossi M, Späth P, et al. Type I hereditary angio-oedema: variability of clinical presentation and course within two large kindreds. J Intern Med 1997;241:39-46
  7. Bowen T, Cicardi M, Bork K, et al. Hereditary angioedema: a current state-of-the art review, VII: Canadian Hungarian 2007 International Consensus Algorithm for the diagnosis, therapy, and management of Hereditary angioedema. Ann Allergy Asthma Immunol 2008;100:30-40
  8. Zuraw BL. Hereditary angioedema: a current state-of-the art review, IV: short- and long-term treatment of hereditary angioedema: out with the old and in with the new? Ann Allergy Asthma Immunol 2008;100:13-18
  9. Frank MM. Hereditary angioedema: the clinical syndrome and its management in the United States. Immunol Allergy Clin North Am. 2006;26:653-68
  10. Cugno M, Zanichelli A, Foieni F, et al. C1-inhibitor deficiency and angioedema: molecular mechanisms and clinical progress. Trends Mol Med 2009;15:69-78
  11. Quastel M, Harrison R, Cicardi M, et al. Behavior in vivo of normal and dysfunctional C1 inhibitor in normal subjects and patients with hereditary angioneurotic edema. J Clin Invest 1983;71:1041-6
  12. Bork K. Hereditary angioedema with normal C1 inhibitor activity including hereditary angioedema with coagulation factor XII gene mutations. Immunol Allergy Clin North Am 2006;26:709-24
  13. Zuraw BL, Bernstein JA, Lang DM, et al. American Academy of Allergy, As