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Journals / İstanbul Tıp Fakültesi Dergisi / 2025 / Cilt: 88 Sayı: 4

FOOD ADDITIVE PATCH TESTING IN CHILDREN WITH ALLERGIC SKIN SYMPTOMS

ALERJİK CİLT SEMPTOMLARI OLAN ÇOCUKLARDA BESİN KATKI MADDELERİ İLE YAMA TESTİ

Güler Yıldırım(Sağlık Bilimleri University, Prof. Dr. Cemil Taşcıoğlu City Hospital, Department of Pediatric Allergy and Immunology)0000-0001-7852-9252
Nilay Çalışkan(Sağlık Bilimleri University, Prof. Dr. Cemil Taşcıoğlu City Hospital, Department of Pediatric Allergy and Immunology)0000-0002-5546-0034
Merve Karaca Şahin(Sağlık Bilimleri University, Prof. Dr. Cemil Taşcıoğlu City Hospital, Department of Pediatric Allergy and Immunology)0000-0001-8783-0514
Hamit Boloğur(Sağlık Bilimleri University, Prof. Dr. Cemil Taşcıoğlu City Hospital, Department of Pediatric Allergy and Immunology)0000-0003-1092-8833
Muhammed Fatih Erbay(Sağlık Bilimleri University, Prof. Dr. Cemil Taşcıoğlu City Hospital, Department of Pediatric Allergy and Immunology)0000-0002-4128-3081
Hilal Güngör(Sağlık Bilimleri University, Prof. Dr. Cemil Taşcıoğlu City Hospital, Department of Pediatric Allergy and Immunology)0000-0002-8923-1897
Şefika İlknur Kökçü Karadağ(Sağlık Bilimleri University, Prof. Dr. Cemil Taşcıoğlu City Hospital, Department of Pediatric Allergy and Immunology)0000-0001-9234-633X
Deniz Özçeker(Sağlık Bilimleri University, Prof. Dr. Cemil Taşcıoğlu City Hospital, Department of Pediatric Allergy and Immunology)0000-0002-0032-6727
Pages
312–320
Publication Date
2025-10-30
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: Performing a FAPT in patients describing symptoms after consuming processed foods may be beneficial; however, further studies are needed to support this issue.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Food additives may cause various allergic symptoms in children; however, there are limited studies investigating sensi tivity to food additives.
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Key Findings & Data:Material and Methods: Data of patients aged 218 years who presented between January 2017 and January 2023, reported allergic symptoms associated with the consumption of prepared and pack aged foods and underwent FAPT were retrospectively recorded.
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Conclusion & Impact:Conclusion: Performing a FAPT in patients describing symptoms after consuming processed foods may be beneficial; however, further studies are needed to support this issue.
🔬Design:Araştırma Makalesi
📍Scope:2017 Verileri
⚙️Variables:Alerji · amarant · çocuklar

Abstract

Objective: Food additives may cause various allergic symptoms in children; however, there are limited studies investigating sensi tivity to food additives. The aim of this study was to evaluate the diagnostic value of food additive patch testing (FAPT) in patients who have detected allergen sensitivity with FAPT and have been recommended a diet. Material and Methods: Data of patients aged 218 years who presented between January 2017 and January 2023, reported allergic symptoms associated with the consumption of prepared and pack aged foods and underwent FAPT were retrospectively recorded. Results: A total of 342 patients who underwent FAPT in our study were evaluated. The positivity rate for at least one allergen among the 342 patients was 28.7%. Amaranth was detected as a suspected allergen in 48 (14.0%) out of 342 patients who underwent FAPT. Among the 98 patients who tested positive for the FAPT, acute/ intermittent urticaria was found in 56 (57.1%) of them. Additionally, confectionery and chocolates were identified as suspicious foods that could cause symptoms in 58 (59.2%) of the 98 patients who tested positive for the FAPT. It was observed that 56.1% of the patients followed a diet after detecting the food additive product, and 46.9% of 98 patients who tested positive for the FAPT benefited from the diet. During the 4month followup, 45 patients (45.9%) who did not fully adhere to their diet experienced a recurrence of symptoms upon consuming the allergen to which they were sensitive. Conclusion: Performing a FAPT in patients describing symptoms after consuming processed foods may be beneficial; however, further studies are needed to support this issue.

Özet

Amaç: Besin katkı maddeleri, çocuklarda çeşitli alerjik semptomlara neden olabilir, ancak besin katkı maddelerine duyarlılığı araştıran çalışmalar sınırlıdır. Bu çalışmanın amacı, besin katkı yama testi (BKYT) ile alerjen duyarlılığı tespit edilen ve diyet önerilen hastalarda BKYT’nin tanısal değerini değerlendirmektir. Gereç ve Yöntemler: Ocak 2017 ile Ocak 2023 tarihleri arasında başvuran, hazır ve paketlenmiş gıdaların tüketimi ile ilişkili alerjik semptomlar bildiren ve BKYT uygulanan 218 yaş arası hastaların verileri retrospektif olarak kaydedildi. Bulgular: Çalışmamızda BKYT uygulanan toplam 342 hasta değer lendirildi. Bu 342 hastanın %28,7′sinde en az bir alerjene pozitiflik tespit edildi. BKYT uygulanan 342 hastanın 48′inde (%14,0) amarant şüpheli alerjen olarak tespit edildi. BKYT’de pozitiflik saptanan 98 hastanın 56′sında (%57,1) akut/aralıklı ürtiker en sık klinik başvuru sebebiydi. Ayrıca, BKYT pozitif olan 98 hastanın 58′inde (%59,2) semptomlara neden olabilecek şüpheli besin olarak şekerlemeler ve çikolata olarak belirlendi. BKYT pozitif olan hastaların %56,1’inin diyet uyguladığı ve %46,9’unun diyetten fayda gördüğü belirlendi. Ayrıca, 4aylık takipte, diyete tam olarak bağlı kalmayan 45 hastada (%45,9) hassasiyet gösterdikleri allerjenin tüketiminde semptom ların tekrar ortaya çıktığı tespit edildi. Sonuç: İşlenmiş gıdaları tükettikten sonra semptom tarifleyen hastalarda BKYT uygulanmasının faydalı olabileceği düşünülmek tedir, ancak bu konuyu destekleyecek daha fazla çalışmaya ihtiyaç vardır.

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Cite This Article

Yıldırım, G., Çalışkan, N., Şahin, M. K., Boloğur, H., Erbay, M. F., Güngör, H., Karadağ, Ş. İ. K., Özçeker, D. (2025). FOOD ADDITIVE PATCH TESTING IN CHILDREN WITH ALLERGIC SKIN SYMPTOMS. İstanbul Tıp Fakültesi Dergisi, Cilt: 88 Sayı: 4, 312–320. https://doi.org/10.26650/IUITFD.1703885

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