Journals / Çocuk Enfeksiyon Dergisi / 2010 / Cilt: 4 - Sayı: 4

Bakteriyel enfeksiyonlarda hemofagositik sendrom

Hemophagocytic syndrome associated with bacterial infections

Pages
162–164
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Here we report three cases of hemophagocytic syndrome (HS) associated with diverse bacterial infections that resolved with appropriate antibacterial therapy.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Hemophagocytic lymphohistiocytosis (HLH) is characterized by systemic proliferation and activation of benign histiocytes showing hemophagocytosis.
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Key Findings & Data:It can be classified as primary and secondary or acquired HLH.
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Conclusion & Impact:Here we report three cases of hemophagocytic syndrome (HS) associated with diverse bacterial infections that resolved with appropriate antibacterial therapy.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Hemophagocytic lymphohistiocytosis (HLH) is characterized by systemic proliferation and activation of benign histiocytes showing hemophagocytosis. It can be classified as primary and secondary or acquired HLH. Secondary HLH is associated with several infections, autoimmune diseases and malignancies. Here we report three cases of hemophagocytic syndrome (HS) associated with diverse bacterial infections that resolved with appropriate antibacterial therapy.

Özet

Hemofagositik lenfohistiyositoz (HLH) benign histiyositlerin proliferasyonu ve aktivasyonu sonucu ortaya çıkan klinik bir tablodur. Familial HLH’nin yanısıra özellikle viral enfeksiyonlar, otoimmün hastalıklar ve malignitelerle ilişkili görülebilir. Burada farklı bakteriyel enfeksiyonlar sırasında HLH tanısı almış ve uygun antibiyotik tedavisi ile düzelen üç olgu sunulmaktadır.

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Cite This Article

YARALI, H. N., YILDIRIM, I., YILMAZ, E. A., ZORLU, P., TANIR, G. (2010). Bakteriyel enfeksiyonlarda hemofagositik sendrom. Çocuk Enfeksiyon Dergisi, Cilt: 4 - Sayı: 4, 162–164. https://ajindex.com/articles/218176

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References (9)

  1. Janka GE. Familial and acquired hemophagocytic lymphohisti-ocytosis. Eur J Pediatr 2007; 166: 95-109
  2. Henter J, Horne AC, Arico M, et al. HLH-2004: diagnostic and therapeutic guidelines for hemophagocytic lymphohistiocyto-sis. Pediatr Blood Cancer 2007; 48: 124-31
  3. Imasshuku S, Hibi S, Todo S. Hemophagocytic lymphohistiocy-tosis in infancy and childhood. J Pediatr 1997; 130: 352-7
  4. Risdall RJ, Brunning RD, Hernandez JI, et al. Bacteria-associated hemophagocytic syndrome. Cancer 1984; 54: 2968-72
  5. Fisman DN. Hemophagocytic syndromes and infection. Emerg Infect Dis 2000; 6: 601-8
  6. Gurgey A, Secmeer G, Tavil B, et al. Secondary hemophago-cytic lymphohistiocytosis in Turkish children. Pediatr Infect Dis J 2005; 24: 1116-7
  7. Chang YH, Lee DS, Jo HS, et al. Tumor necrosis factor alpha promoter polymorphism associated with increased susceptibil-ity to secondary hemophagocytic lymphohistiocytosis in the Korean population.Cytokine 2006; 36: 45-50
  8. Janka GE, Schneider EM. Modern management of children with haemophagocytic lymphohistiocytosis. Br J Haematol 2004; 124: 4-14
  9. Domachowske JB. Infectious triggers of hemophagocytic syn-drome in children. Ped Infect Dis J 2006: 25; 1067-8.