Journals / Ege Klinikleri Tıp Dergisi / 2020 / Cilt: 58 - Sayı: 3

Investigation of the Relationship Between Vital Parameters and Procalcitonin Values With Blood Cültüre Reproduction in Patients Admitted to the Emergency Department With Sepsis

Acil Servise Sepsis Öntanısı İle Başvuran Hastaların Geliş Vital Parametreleri Ve Prokalsitonin Değerlerinin Kan Kültürü Üremeleriyle Olan İlişkisinin Araştırılması

Pages
338–343
DOI
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Conclusions: As a result of our study, we determined that any vital parameter or serum PCT level was not successful in predicting blood culture results, but serum PCT value could be used to estimate gram (-) bacteremia when the nonreproductive group and the group with gram (-) reproduction were compared.

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: In this study, we aimed to predict blood culture positivity of patients admitted to Marmara University Department of Emergency Medicine with the preliminary diagnosis of sepsis with their vital parameters and serum Geliş procalcitonin(PCT) levels.
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Key Findings & Data:Method: This single center, prospective study involved 131 hospitalized patients who met two or more criteria for Quick Sofa (qSOFA) during the period between October 2018 and April 2019 in the Marmara University Emergency Department.
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Conclusion & Impact:Conclusions: As a result of our study, we determined that any vital parameter or serum PCT level was not successful in predicting blood culture results, but serum PCT value could be used to estimate gram (-) bacteremia when the nonreproductive group and the group with gram (-) reproduction were compared.
🔬Design:Research Article
📍Scope:2018 Verileri
⚙️Variables:Domain Parameters

Abstract

Aim: In this study, we aimed to predict blood culture positivity of patients admitted to Marmara University Department of Emergency Medicine with the preliminary diagnosis of sepsis with their vital parameters and serum Geliş procalcitonin(PCT) levels. Method: This single center, prospective study involved 131 hospitalized patients who met two or more criteria for Quick Sofa (qSOFA) during the period between October 2018 and April 2019 in the Marmara University Emergency Department. The vital parameters of the study patients were recorded and blood tests including PCT, blood cultures and other necessary cultures were taken from the patients and sent to the laboratory. Results: We seperated 131 septic patients into three groups according to their blood culture results. There was no statistically significant difference between the vital parameters of these three groups. When we compared the PCT values of these three groups, we found a statistically significant difference. The median value of PCT in the gram-negative bacterial reproduction in blood culture was 2.2 μg / L (ICA 0.5-13), in the gram-positive bacterial reproduction in blood culture was 5.2 μg / L (ICA 1.6- 24.8) and in the contamination group 0.8 μg / L (ICA 0.3-4.3). According to the Dwass-Steel Critchlow-Fligner method, we found that this difference was due to positive blood culture and contamination group (p = 0.01). Conclusions: As a result of our study, we determined that any vital parameter or serum PCT level was not successful in predicting blood culture results, but serum PCT value could be used to estimate gram (-) bacteremia when the nonreproductive group and the group with gram (-) reproduction were compared.

Özet

Amaç: Çalışmamızda Marmara Üniversitesi Acil Tıp Anabilim Dalına Başvuran ve sepsis ön tanısı ile takip ettiğimiz hastaların kan kültür pozitifliklerini hastaların geliş vital parametreleri ve serum prokalsitonin( PCT) düzeyleri ile önceden tahmin etmek amaçlandı. Yöntem: Marmara Üniversitesi acil servisinde, 05.10.2018 ile 31.03.2019 tarihleri arasında, tek merkezli, prospektif ve gözlemsel olarak yürüttüğümüz bu çalışmaya qSOFA kriterlerinden an az 3 ‘te 2 sinin pozitif olduğu ve dışlama kriterlerine sahip olmayan 131 sepsis hastası dahil edildi. Çalışma hastalarının geliş vital parametreleri kaydedilip, bu hastalardan PCT dahil olmak üzere kan tetkikleri, kan kültürleri ve gerekli diğer kültürleri alınarak laboratuvara gönderildi. Bulgular: Çalışmaya dahil edilen 131 sepsis hastası kan kültür sonuçlarına göre üreme olan, üreme olmayan ve kan kültürü kontamine olarak sonuçlanan olarak üç gruba ayrıldı. Bu üç grubun geliş vital parametreleri arasında istatiksel olarak anlamlı fark yoktu. Bu üç grubun PCT değerlerini karşılaştırıldığında ise istatiksel olarak anlamlı bir fark bulundu. Üreme olmayan grupta PCT medyan değeri 2,2 μg/L (İKA 0,5-13), üreme olan grupta 5,2 μg/L (İKA 1,6-24,8) ve kontaminasyonun olduğu grupta 0,8 μg/L (İKA 0,3-4,3) olarak tespit edildi. Dwass-Steel-Critchlow-Fligner ikili karşılaştırmasına göre bu farkın üreme olan ve kontaminasyon grubundan kaynaklandığı saptandı (p=0.01). Sonuç: Çalışmamızın sonucunda ise herhangi bir vital parametrenin ya da serum PCT düzeyinin kan kültür sonucunu önceden tahmin etme konusunda başarılı olmadığı ama üreme olmayan grup ile gram (-) üreme olan grup karşılaştırıldığında serum PCT değeri gram (-) bakteremiyi tahmin etmede kullanılabileceği tespit edildi.

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Cite This Article

ÖZTÜRK, Y., ÖZPOLAT, Ç., AKOĞLU, H., ONUR, O., DENİZBAŞI, A. (2020). Investigation of the Relationship Between Vital Parameters and Procalcitonin Values With Blood Cültüre Reproduction in Patients Admitted to the Emergency Department With Sepsis. Ege Klinikleri Tıp Dergisi, Cilt: 58 - Sayı: 3, 338–343. https://ajindex.com/articles/217840

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