SavedAdd your journal

Journals / GORM:Gynecology Obstetrics & Reproductive Medicine / 2011 / Cilt: 17 - Sayı: 3

Artmış nukal kalınlığın eşlik ettiği cantrell pentalojisinin prenatal tanısı: Olgu sunumu

Prenatal diagnosis of pentalogy of cantrell with increased nuchal translucency: Case report

Deniz Cemgil ARIKAN
Semih YANCAR
Fethi GÜÇER
Ender ZENCİR
Hakan BEYAZIT
Pages
173–176
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Increased NT measurement in first trimester of pregnancy may also bring the fetus to early attention for pentology of Cantrell if an omphalocele associates with this condition.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Pentalogy of Cantrell is a rare sporadic syndrome with unknown etiology.
📊
Key Findings & Data:We aimed to present a prenatally diagnosed case of pentalogy of Cantrell associated with increased nuchal translucency (NT).
💡
Conclusion & Impact:Increased NT measurement in first trimester of pregnancy may also bring the fetus to early attention for pentology of Cantrell if an omphalocele associates with this condition.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Pentalogy of Cantrell is a rare sporadic syndrome with unknown etiology. We aimed to present a prenatally diagnosed case of pentalogy of Cantrell associated with increased nuchal translucency (NT). A twenty-two year old G2P0A1 pregnant woman was admitted to our clinic for routine prenatal ultrasonographic scanning at 14th weeks of gestation. Ultrasound scan revealed a NT of 7.9 mm and a large omphalocele containing the liver, bowel, and heart with ventricular septal defect. After taking the written informed consent form the parents the pregnancy was terminated. Postmortem examination confirmed the ultrasound findings and chromosome analysis revealed a normal karyotype. Increased NT measurement in first trimester of pregnancy may also bring the fetus to early attention for pentology of Cantrell if an omphalocele associates with this condition.

Özet

Cantrell pentalojisi etyolojisi bilinmeyen nadir bir sporadik sendromdur. Biz bu olgu sunumunda, artmış nukal kalınlığın eşlik ettiği ve prenatal tanısı konmuş Cantrell Pentalojisi olgusunu sunmayı amaçladık. Yirmi-iki yaşında G2P0A1 olan gebe gebeliğinin 14. haftasında rutin prenatal ultrason taraması için kliniğimize başvurdu. Ultrasonografik incelemede 7,9 mm olan nukal kalınlık ve karaciger, barsak ve ventriküler septal defektin saptandığı kalbi de içeren büyük bir omfalosel izlendi. Anne ve babanın yazılı onayı alındıktan sonra gebelik sonlandırıldı. Postmortem incelemede ultrason bulguları doğrulandı ve kromozom analizinde normal karyotip saptandı. Gebeliğin ilk trimesterinde saptanan artmış nukal kalınlığa omfaloselin de eşlik etmesi, fetusta Cantrell pentalojisi için erken dikkat edilmesini sağlayabilir.

🔖

Cite This Article

ARIKAN, D. C., YANCAR, S., GÜÇER, F., ZENCİR, E., BEYAZIT, H. (2011). Artmış nukal kalınlığın eşlik ettiği cantrell pentalojisinin prenatal tanısı: Olgu sunumu. GORM:Gynecology Obstetrics & Reproductive Medicine, Cilt: 17 - Sayı: 3, 173–176. https://ajindex.com/articles/216913

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (15)

  1. Cantrell JR. Haller JA. Ravitch MM. A syndrome of congenital defects involving the abdominal wall, sternum, diaphragm, pericardium and heart. Surg Gynecol Obstet 1958;107:602-14
  2. Carmi R, Boughman JA. Pentalogy of Cantrell and associated midline anomalies: a possible ventral midline developmental field. Am J Med Genet 1992;42:90-5
  3. Martin RA. Cunniff C. Erickson L. et al. Pentalogy of Cantrell and ectopia cordis, a familial developmental field complex. Am J Med Genet 1992;42:839-41
  4. Hornberger LK. Colan SD. Lock JE. et al. Outcome of patients with ectopia cordis and significant intracardiac defects. Circulation 1996;94:32-7
  5. Loureiro T. Oliveira C. Aroso J. et al. Prenatal sonographic diagnosis of a rare Cantrell’s pentalogy variant with associated open neural tube defect-a case report. Fetal Diagn Ther 2007;22:172-4
  6. Toyama WM. Combined congenital defects of the anterior abdominal wall, sternum, diaphragm, pericardium and heart: a case report and review of the syndrome. Pediatrics 1972;50:778-92
  7. Fernández MS. López A. Vila JJ. et al. Cantrell’s pentalogy. Report of four cases and their management. Pediatr Surg Int 1997;12:428-31
  8. Liang RI. Huang SE. Chang FM. Prenatal diagnosis of ectopia cordis at 10 weeks of gestation using two-dimensional and three-dimensional ultrasonography. Ultrasound Obstet Gynecol 1997;10:137-9
  9. Staboulidou I. Wüstemann M. Schmidt P. et al. Increased fetal nuchal translucency as a predictor of Cantrell's pentology- case report. Z Geburtshilfe Neonatol 2005;209: 231-4
  10. Markov D. Chernev T. Dimitrova V. et al. Pentalogy of Cantrell associated with increased nuchal translucency at 12+1 w.g. Akush Ginekol (Sofiia) 2004;43:34-6
  11. Zidere V. Allan LD. Changing findings in pentalogy of Cantrell in fetal life. Ultrasound Obstet Gynecol 2008;32: 835-7
  12. Bhat RY. Rao A. Muthuram. Cantrell syndrome in one of a set of monozygotic twins. Singapore Med J 2006;47: 1087-8
  13. Siles C. Boyd PA. Manning N. et al. Omphalocele and pericardial effusion: possible sonographic markers for the pentalogy of Cantrell or its variants. Obstet Gynecol 1996; 87:840-2
  14. Hertzberg BS.Nyberg DA. Neilsen IR. Ventral wall defects. In: NybergDA, McGahan JP, Pretorius DH, Pilu G, eds. Diagnostic Imaging of Fetal Anomalies. Philadelphia: Lippincott Williams & Wilkins 2003:507-46
  15. Benaceraff VR. Saltzman DH. Esteroff JA. Frigoleto FD Jr. Abnormal karyotype of fetuses with Omphalocele: prediction based on omphalocele contents.