Journals / Flora İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi / 2001 / Cilt: 6 - Sayı: 2

Extended spectrum beta-lactamase production in Salmonella isolates

Salmonella izolatlarında genişlemiş spektrumlu beta-laktamaz yapımı

Pages
114–117
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We reccomend that in clinical microbology laboratories where ESBL production tests are not in routine practice, special attention should be given to Salmonella spp. obtained from neonatal infections, hospitalized patients and systemic infections, for the probability of ESBL production.

📌 3 Key Takeaways

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Objective & Hypothesis:Extended spectrum beta-lactamases (ESBL) are enzymes that are also noticed among Salmonella species of the Enterobacteriaceae family.
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Key Findings & Data:In our study, 70 ampicillin resistant Salmonella strains isolated in Clinical Microbiology Laboratory of Hacettepe University ihsan Doğramacı Children's Hospital [Salmonella serogrup b (57), Salmonella serogrup d (10), Salmonella typhi (3)] obtained from children in hospital wards or outpatient clinics, were evaluated for ESBL production by double disk synergy technique.
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Conclusion & Impact:We reccomend that in clinical microbology laboratories where ESBL production tests are not in routine practice, special attention should be given to Salmonella spp. obtained from neonatal infections, hospitalized patients and systemic infections, for the probability of ESBL production.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Salmonella · beta-Laktamazlar · Mikrobiyolojik teknikler

Abstract

Extended spectrum beta-lactamases (ESBL) are enzymes that are also noticed among Salmonella species of the Enterobacteriaceae family. In our study, 70 ampicillin resistant Salmonella strains isolated in Clinical Microbiology Laboratory of Hacettepe University ihsan Doğramacı Children's Hospital [Salmonella serogrup b (57), Salmonella serogrup d (10), Salmonella typhi (3)] obtained from children in hospital wards or outpatient clinics, were evaluated for ESBL production by double disk synergy technique. Twenty-four isolates (17 of them being hospital isolates), were found to produce ESBL. In addition to multiple resistant strains, increasing ESBL production among Salmonella species seems to produce potential health problems in our country. We reccomend that in clinical microbology laboratories where ESBL production tests are not in routine practice, special attention should be given to Salmonella spp. obtained from neonatal infections, hospitalized patients and systemic infections, for the probability of ESBL production.

Özet

Genişlemiş spektrumlu beta-laktamaz (ESBL) yapımı klinik önemi olan birçok gram-negatif mikroorganizma gibi, Enterobacteriaceae ailesinin bir üyesi olan Salmonella türlerinde de dikkati çeken bir özellik olmaya başlamıştır. Çalışmamızda Hacettepe Üniversitesi ihsan Doğramacı Çocuk Hastanesi Klinik Mikrobiyoloji Laboratuvarı 'nda izole edilmiş olan Salmonella serogrup b (57), Salmonella serogrup d (10), Salmonella typhi (3)'den oluşan 70 adet ampisilin dirençli servis ve poliklinik izolatında çift disk sinerji yöntemiyle ESBL varlığı araştırılmış ve 17 tanesi servis izolatı olan 24 tanesinde ESBL varlığı gösterilmiştir. Çoğul dirençli suşların yanısıra ESBL üretimi, ülkemizdeki Salmonella infeksiyonlarının önümüzdeki yıllarda önemli bir halk sağlığı problemi olarak karşımıza çıkacabileceğini düşündürmektedir. ESBL araştırılmasının rutin pratiğe sokulmamış olduğu klinik mikrobiyoloji laboratuvarında özellikle hastane İzolatlarında, sistemik infeksiyonlardan elde edilen suşlarda ve yenidoğan infeksiyonlarında ESBL varlığının araştırılması açısından dikkatli olunmalıdır.

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Cite This Article

AKAN, A. Ö., KUZUCU, Ç., BAKTIR, E., ACAR, N. (2001). Extended spectrum beta-lactamase production in Salmonella isolates. Flora İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi, Cilt: 6 - Sayı: 2, 114–117. https://ajindex.com/articles/214804

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