AI Summary & Key Takeaways
AI InsightHistopathological examinations should be performed by experi- enced pathologists
📌 3 Key Takeaways
Abstract
Malignant gastrointestinal stromal tumors are rare mesenchymal tumors originating from the gastroin- testinal tract. Making a differential diagnosis with gynecologic masses may be difficult in the preopera- tive period. The patient was a 45- year-old woman who presented to our clinic with a palpable mass fill- ing the pelvis. The CA 125 value was 42.7 U/ml. She underwent right hemicolectomy, total omentectomy, total abdominal hysterectomy, bilateral salpingo-oophorectomy and bilateral pelvic and para-aortic lymph node dissection since the frozen section assessment of the biopsy from the right colon was re- ported as a tumoral mass probably originating from the ovary. Tumoral tissue showed diffuse cytoplas- mic membraneous staining immunohistochemically with CD117, showed strong focal strong cytoplasmic staining with SMA. It was stained negative with desmin, S-100 and CD34. Molecular analysis of KIT gene was performed, we didn't detect mutations of exon 9 or 11. Surgical exploration of pelvic masses with undetermined origins should be performed in multidiciplinary hospitals including gynecological on- cology and surgical oncology teams. Histopathological examinations should be performed by experi- enced pathologists