Journals / İzmir Tepecik Eğitim Hastanesi Dergisi / 2015 / Cilt: 25 - Sayı: 1

Evaluation of anemia in geriatric inpatients

Hastanede yatan geriyatrik hastalarda aneminin değerlendirilmesi

Pages
43–48
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The most common underlying cause of anemia is identified as ACI in compliance with literature findings.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: The number of chronic diseases, including anemia, increase with aging.
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Key Findings & Data:While the incidence of anemia is around 10% in adults at or above 65 years of age, it increases to 20-25% in subjects at or above 85 years of age and to almost 40-50% among inpatients.
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Conclusion & Impact:The most common underlying cause of anemia is identified as ACI in compliance with literature findings.
🔬Design:Review & Systematic Survey
📍Scope:2011 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: The number of chronic diseases, including anemia, increase with aging. While the incidence of anemia is around 10% in adults at or above 65 years of age, it increases to 20-25% in subjects at or above 85 years of age and to almost 40-50% among inpatients. There is scarce evidence in our county describing the incidence of anemia in geriatric patients. This study aims to evaluate anemia in geriatric inpatient settings. Methods: A retrospective review was completed to identify inpatients at or above 65 years of age who had received treatment at a general internal medicine and geriatric inpatient department from 01.01.2011 to 06.30.2013. Demographic data, chronic diseases, medications used, hospitalization period and underlying causes were recorded. Patients were divided into three groups, including young old, old-old and the oldest patients. Anemia was defined as hemoglobin (Hb) values below 13 g/dL for male subjects and below 12 g/dL for female subjects. In our study, the lower limit of normal (LLN) was 200 pmol/L for Vitamin B12 and 4 nmol/L for folic acid. Baseline laboratory values were evaluated. Chronic disease anemia was defined as serum ferritin level > 100 µg/L and transferrin saturation >20%, while anemia secondary to chronic renal failure was defined as glomerular filtration rate (GFR) <30 ml/ min. Iron deficiency anemia was characterized as serum ferritin level <45 µg/L and transferrin saturation <20 percent. Diagnoses based on hematologic pathology were made in consideration of the results of peripheral smear and bone marrow biopsy. Results: The mean age of 148 patients enrolled in the study was 78.75±7.46 years. Of all patients, 31.7% were young old, 42.8% old-old. Female elderly accounted for 50.6% of the patients. Mean hospitalization period was 15±14.8 days. Of all patients, 76.3% were anemic. This study demonstrated that in our patients underlying causes of anemia were Anemia of chronic inflammation (ACI) (53.9%) hematological malignancies (15%) and iron deficiency anemia (13.2%) in decreasing order of frequency. Conclusion: The incidence of anemia was detected to be remarkably high (76.3%) in a geriatric population treated in an inpatient setting. The most common underlying cause of anemia is identified as ACI in compliance with literature findings.

Özet

Amaç: Yaşlanmayla birlikte kronik hastalıkların sayısı ve sıklığı da artmaktadır. Yaşlanmayla sıklığı artan hastalıklardan birisi de anemidir. Literatürde toplumda yaşayan 65 yaş ve üzeri yetişkinlerde anemi oranının %10 olduğu, bu oranın 85 yaş ve sonrasında ise %20-25’lere çıktığı gösterilmiştir. Hastanede yatan hastalarda ise anemi oranı %40-50 arasındadır. Ülkemizde yatan geriatrik yaşlılardaki anemi sıklığı ile ilgili çalışmalar kısıtlıdır. Bu çalışmada, farklı nedenlerle hastanede yatan geriatri hastalarında aneminin değerlendirilmesi amaçlanmıştır. Yöntemler: Genel dâhiliye ve geriatri servisimizde 01/01/2011 ve 30/06/2013 tarihleri arasında yatarak tedavi gören 65 yaş ve üzeri hastalar retrospektif olarak taranmıştır. Demografik veriler, kronik hastalık kullanılan ilaçlar, hastanedeki yatış süresi ve nedeni kaydedilmiştir. Erkeklerde 13 g/dl’nin, kadınlarda ise 12 g/dl’nin altındaki hemoglobin (Hb) değerleri anemi, olarak sınıflandırılmıştır. B12 vit için alt sınır 200 p mol/L’, folik asit için 4 nmol/L olarak alınmıştır. Hastaneye yatıştaki laboratuvar değerleri değerlendirmeye alınmıştır. Kronik hastalık anemisi; serum ferritin düzeyinin 100 µg/L’den fazla, transferrin saturasyonunun %20’den fazla olması, kronik böbrek yetmezliğine ikincil anemi ise GFR’nin 30 ml/dk.’nın altı olarak tanımlanmıştır. Demir eksikliği anemisi ise serum ferritin düzeyinin 45 µg/litreden ve transferrin saturasyonunun %20’den az olması olarak tanımlanmıştır. Hematolojik patoloji tanısı periferik yayma ve kemik iliği biyopsisi ile koyulmuştur. Bulgular: Çalışmaya alınan 148 hastanın yaş ortalaması 78,75±7,46 yıldı. Hastaların %31,7’si genç yaşlı, %42.8’si orta yaşlıydı. Yüzde 50,6’sı kadındı. Hastaların servise yatış günleri ortalama 15±14,8 gün idi. Hastaların % 76,3’ünde anemi mevcuttu. Çalışmamızda, aneminin nedeni sırasıyla kronik hastalık anemisi %53,9, hematolojik maligniteler %15 ve demir eksikliği anemisi %13,2 olarak saptandı. Sonuç: Yatarak tedavi gören geriatrik popülasyonda anemi sıklığı %76,3 gibi yüksek bir oran olarak saptanmıştır. En sık anemi nedeni literatürle uyumlu olarak kronik hastalık anemisi olarak bulunmuştur.

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Cite This Article

TOSUN, P. T., ŞAHİN, S., EMGİN, Ö., KEKLİK, F., AYDOĞAN, B., DUMAN, S., AKÇİÇEK, F. (2015). Evaluation of anemia in geriatric inpatients. İzmir Tepecik Eğitim Hastanesi Dergisi, Cilt: 25 - Sayı: 1, 43–48. https://ajindex.com/articles/213773

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