Journals / Dicle Tıp Dergisi / 2015 / Cilt: 42 - Sayı: 4

Relationship of intima-media thickness with Gensini score that determines the severity of coronary artery disease

Karotis intima-media kalınlığının koroner arter hastalık şiddetini belirleyen Gensini skoru ile ilişkisi

Pages
501–505
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

As a non-invasive measurement CIMT can be used as an additional method in recognition of severe coronary artery disease

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: In this study we aimed to compare carotid intima-media thickness (CIMT) with Gensini score which objective evidence to demonstrate the severity of coronary artery disease.
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Key Findings & Data:Methods: The study included 76 CAD patients (41 men, 35 women, mean age 60.7±11.2 years, range: 42-83) We calculated the Gensini score and measured CIMT for each patient, CAD patients was separated into two groups: patients with mild atherosclerosis (Gensini score <25 points) and severe atherosclerosis (Gensini score &#8805;25 points).
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Conclusion & Impact:As a non-invasive measurement CIMT can be used as an additional method in recognition of severe coronary artery disease
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: In this study we aimed to compare carotid intima-media thickness (CIMT) with Gensini score which objective evidence to demonstrate the severity of coronary artery disease. Methods: The study included 76 CAD patients (41 men, 35 women, mean age 60.7±11.2 years, range: 42-83) We calculated the Gensini score and measured CIMT for each patient, CAD patients was separated into two groups: patients with mild atherosclerosis (Gensini score <25 points) and severe atherosclerosis (Gensini score &#8805;25 points). The CIMT values were compared to Gensini score (CAD severity). Results: The severe atherosclerosis group had significantly higher CIMT values compared to the mild atherosclerosis group [(1.2±0.16 range: 0.90-1.50), (0.97±0.07 range: 0.90-1.10), p<0.01, respectively]. There was a significant correlation with CIMT and Gensini score, age, BMI, LDL cholesterol [(r= 0.365, p<0.01), (r=0.327, p=0.03), (r=-0.341, p<0.01), (r=0.385, p<0.01), respectively. Conclusion: We found a significant association between CIMT and Gensini score which objective evidence to severity of CAD. As a non-invasive measurement CIMT can be used as an additional method in recognition of severe coronary artery disease

Özet

Amaç: Bu çalışmada karotis intima media kalınlığının (KİMK) koroner arter hastalarında (KAH) hastalığın ciddiyetini göstermede objektif bir bulgu olan Gensini skoru ile ilişkisini araştırmayı amaçladık. Yöntemler: Göğüs ağrısı nedeniyle kardiyoloji kliniğine başvurmuş, koroner anjiyografisi yapılarak KAH tespit edilen 76 hasta (41 erkek, 35 kadın) (yaş ortalaması 60.7±11.2 yıl; yaş aralığı 42-83 yıl) çalışmaya dahil edildi. Tüm hastalarda Gensini skoru hesaplanarak <25 (hafif KAH) ve ≥25 (ciddi KAH) olmak üzere 2 gruba ayrıldı. Tüm gruplarda KİMK ölçüldü. Gruplar arasında KİMK ile gensini skoru (KAH şiddeti) karşılaştırıldı. Bulgular: Ciddi KAH grubu ile hafif KAH grubu karşı- laştırıldığında, ciddi KAH gurubunda KİMK anlamlı dü- zeyde yüksekti [sırasıyla 1,2±0,16 (aralık: 0,90-1,50) ve 0,97±0,07 (aralık: 0,90-1,10), p <0,01]. KİMK ile Gensini skoru, yaş, vücut kitle indeksi (VKİ) ve LDL kolesterol arasında anlamlı korelasyonunlar saptandı [sırasıyla, r=0,365, p<0,01; r=0,327, p=0,03; r=-0,341, p<0,01; ve r= 0,385, p<0,01). Sonuç: Koroner arter hastalarında hastalığın ciddiyetini belirlemede kullanılan objektif bir kriter olan Gensini skoru ile KİMK arasında anlamlı bir ilişki bulundu

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Cite This Article

ALAN, B., HATTAPOĞLU, S., DUSAK, A., AKTAN, A. (2015). Relationship of intima-media thickness with Gensini score that determines the severity of coronary artery disease. Dicle Tıp Dergisi, Cilt: 42 - Sayı: 4, 501–505. https://ajindex.com/articles/213575

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