Journals / Düşünen Adam - Psikiyatri ve Nörolojik Bilimler Dergisi / 2013 / Cilt: 26 - Sayı: 3

Antidepresan kesilmesine bağlı mani/hipomani

Mania/hypomania associated with withdrawal of antidepressants

Pages
303–306
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Although paradoxical mania/hypomania due to sertraline and paroxetine withdrawal are reported individually, we will discuss a patient with paradoxical mania/ hypomania due to withdrawal of both antidepressants administered at two different time periods, since this is the only case reported so far.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Although paradoxical mania/hypomania due to antidepressant withdrawal is rarely reported in the literature as case report, it is possible that it may be observed more commonly in the clinical settings.
📊
Key Findings & Data:Paradoxical mania/hypomania is reported to be associated with tricyclic antidepressants as well as selective serotonin reuptake inhibitors and other antidepressants.
💡
Conclusion & Impact:Although paradoxical mania/hypomania due to sertraline and paroxetine withdrawal are reported individually, we will discuss a patient with paradoxical mania/ hypomania due to withdrawal of both antidepressants administered at two different time periods, since this is the only case reported so far.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Although paradoxical mania/hypomania due to antidepressant withdrawal is rarely reported in the literature as case report, it is possible that it may be observed more commonly in the clinical settings. Paradoxical mania/hypomania is reported to be associated with tricyclic antidepressants as well as selective serotonin reuptake inhibitors and other antidepressants. Although paradoxical mania/hypomania due to sertraline and paroxetine withdrawal are reported individually, we will discuss a patient with paradoxical mania/ hypomania due to withdrawal of both antidepressants administered at two different time periods, since this is the only case reported so far.

Özet

Antidepresan kesilmesi sonrası “paradoksal” mani/hipomani, literatürde az sayıda olgu bildirimi şeklinde yer almakla birlikte, klinikte daha sık karşılaşılıyor olması muhtemeldir. Sıklıkla trisiklik antidepresanlarla (TSA) bildirilmiş olup, selektif serotonin geri alım inhibitörleri (SSGİ) ve daha nadir olarak diğer antidepresanlarla da bildirilmiştir. Sertralin ve paroksetin kesilmesine bağlı bildirilmiş olgular olmakla birlikte, aynı hastada farklı dönemlerde hem sertralin hem de paroksetin kesilmesine bağlı gelişen manik dönem olarak literatürdeki bilinen tek örnek olması açısından ilginç olduğunu düşündüğümüz bir olgu tartışılmıştır.

🔖

Cite This Article

GÜDÜK, M., ERENSOY, İ. Y., ERSÜMER, F. (2013). Antidepresan kesilmesine bağlı mani/hipomani. Düşünen Adam - Psikiyatri ve Nörolojik Bilimler Dergisi, Cilt: 26 - Sayı: 3, 303–306. https://ajindex.com/articles/212857

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (14)

  1. Ali S, Milev R. Switch to mania upon discontinuation of antidepressants in patients with mood disorders: a review of the literature. Can J Psychiatry 2003; 48:258-264
  2. Zajecka J, Tracy KA, Mitchell S. Discontinuation symptoms after treatment with serotonin reuptake inhibitors: a literature review. J Clin Psychiatry 1997; 58:291-297
  3. Andrade C. Antidepressant-withdrawal mania: a critical review and synthesis of the literature. J Clin Psychiatry 2004; 65:987- 993
  4. Narayan V, Haddad PM. Antidepressant discontinuation manic states: a critical review of the literature and suggested diagnostic criteria. J Psychopharmacol 2011; 25:306-313
  5. Altintoprak AE, Sertoz OO, Coskunol H. Antidepressantdiscontinuation induced mania: A case report and review of the literature. Bulletin of Clinical Psychopharmacology 2006; 16:245-251 (in Turkish)
  6. Dilsaver SC, Greden JF. Antidepressant withdrawal-induced activation (hypomania and mania): mechanism and theoretical significance. Brain Res 1984; 319:29-48
  7. Goldstein TR, Frye MA, Denicoff KD, Smith-Jackson E, Leverich GS, Bryan AL, Ali SO, Post RM. Antidepressant discontinuationrelated mania: critical prospective observation and theoretical implications in bipolar disorder. J Clin Psychiatry 1999; 60:563- 567
  8. Kora K, Kaplan P. Antidepressant-discontinuation induced hipomania/mania. Turk Psikiyatri Derg 2008; 19:329-333 (in Turkish)
  9. Akiskal HS, Hantouche EG, Allilaire JF, Sechter D, Bourgeois ML, Azorin JM, Chatenêt-Duchêne L, Lancrenon S. Validating antidepressant-associated hypomania (bipolar III): a systematic comparison with spontaneous hypomania (bipolar II). J Affect Disord 2003; 73:65-74
  10. Ghaemi SN, Ko JY, Goodwin FK. The bipolar spectrum and the antidepressant view of the world. J Psychiatr Pract 2001; 7:287- 297
  11. MacCall C, Callender J. Mirtazapine withdrawal causing hypomania. Br J Psychiatry 1999; 175:390
  12. Fava GA, Mangelli L. Mania associated with venlafaxine discontinuation. Int J Neuropsychopharmacol 2003; 6:89-90
  13. Michael N, Erfurth A, Arolt V. A case report of mania related to discontinuation of bupropion therapy for smoking cessation. J Clin Psychiatry 2004; 65:277
  14. Tamam L. Selective rerotonin reuptake inhibitor discontinuation syndromes. Clinical Psychiatry 2001; 4:102-111 (in Turkish).