Journals / Glokom Katarakt / 2013 / Cilt: 8 - Sayı: 4

The effect of cataract on peripapillary retinal nerve fiber layer thickness measurements taken with spectral-domain optical coherence tomography

Kataraktın spektral-domain optik koherens tomografiyle yapılan peripapiller retinal sinir lifi tabakası kalınlığı ölçümlerine etkisi

Pages
231–234
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

So, RNFL thickness measurements should be interpreted cautiously in eyes with cataract.

📌 3 Key Takeaways

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Objective & Hypothesis:Purpose: To evaluate the effect of cataract on peripapillary retinal nerve fiber layer (RNFL) thickness measurements taken with spectral-domain optical coherence tomography (OCT).
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Key Findings & Data:Materials and Methods: In this prospective study thirty eyes of 30 patients who underwent uneventful phacoemulsification and intraocular lens implantation surgery were included.
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Conclusion & Impact:So, RNFL thickness measurements should be interpreted cautiously in eyes with cataract.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Purpose: To evaluate the effect of cataract on peripapillary retinal nerve fiber layer (RNFL) thickness measurements taken with spectral-domain optical coherence tomography (OCT). Materials and Methods: In this prospective study thirty eyes of 30 patients who underwent uneventful phacoemulsification and intraocular lens implantation surgery were included. Peripapillary RNFL thickness measurements were taken before and after cataract surgery using high-resolution OCT (Spectralis OCT, Heidelberg Engineering, Heidelberg, Germany). Temporal (T), temporal superior (TS), temporal inferior (TI), nasal (N), nasal superior (NS), nasal inferior (NI) quadrant and global (G) RNFL thickness values were evaluated before and after surgery. Paired-sample t-test was used for statistical analysis. Results: Of the 30 patients 16 (53.3%) were man, 14 (46.7%) were woman. Mean age was 65.1±12.7 years. Before cataract surgery mean RNFL thickness was 80.2±29.4 μ in T, 122.7±33.6 μ in TS, 123.3±46.3 μ in TI, 78.2±31.5 μ in N, 101.3±23.8 μ in NS, 103.7±44.3 μ in NI and 96.1±25.9 μ in G. After cataract surgery RNFL thickness was 81.1±37.4 μ in T, 124.6±39.3 μ in TS, 132.3±37.3 μ in TI, 90.2±47.0 μ in N, 105.3±41.6 μ in NS, 124.2±57.8 μ in NI and 103.9±36.5 μ in G.In all quadrants and globally mean RNFL thickness was measured higher after surgery. However, it was statistically significant in only NI group (p=0.007). There was no statistically significant difference in all RNFL thickness measurements after surgery (p>0.05). Conclusion: In eyes with cataract, RNFL thickness may be measured thinner when using spectralis OCT. So, RNFL thickness measurements should be interpreted cautiously in eyes with cataract.

Özet

Amaç: Kataraktın spektral domain optik koherans tomografi (OKT) ile peripapiller retinal sinir lifi tabakası (RSLT) kalınlığı ölçümlerine etkisini incelemek. Gereç ve Yöntem: Kliniğimizde Ocak 2011-Ocak 2012 tarihleri arasında komplikasyonsuz fakoemülsifikasyon ve intraoküler lens implantasyonu ameliyatı yapılan 30 hastanın 30 gözü çalışmaya alındı. Katarakt cerrahisinden önce ve sonra yüksek rezolüsyonlu OKT (Spectralis OCT, Heidelberg Engineering, Heidelberg, Germany) kullanılarak peripapiller RSLT kalınlığı ölçümü yapıldı. Temporal (T), temporal süperior (TS), temporal inferior (Tİ), nazal (N), nazal süperior (NS), nazal inferior (Nİ) kadran, and global (G) RSLT tabakası kalınlık değerleri hesaplandı ve katarakt cerrahisi öncesi ve sonrası karşılaştırıldı. İstatistiksel analizde bağımlı gruplarda t-testi kullanıldı. Bulgular: Otuz hastanın 16’sı (%53.3) erkek, 14’ü kadındı. Ortalama yaş 65.1±12.7 yıldı. Katarakt cerrahisi öncesi RSLT kalınlığı T’da 80.2±29.4 μ, TS’da 122.7±33.6 μ, Tİ’da 123.3±46.3 μ, N’da 78.2±31.5 μ, NS’da 101.3±23.8 μ, Nİ’da 103.7±44.3 μ ve G’de 96.1±25.9 μ. Katarakt cerrahisi öncesi RSLT kalınlığı T’da 81.1±37.4 μ, TS’da 124.6±39.3 μ, Tİ’da 132.3±37.3 μ, N’da 90.2±47.0 μ, NS’da 105.3±41.6 μ, Nİ’da 124.2±57.8 μ ve G’de 103.9±36.5 μ. Tüm kadranlarda ve global olarak ortalama RSLT kalınlığı katarakt cerrahisi sonrası daha kalın ölçüldü. Buna rağmen sadece Nİ grup istatistiksel olarak anlamlı bulundu (p=0.007). Diğer kadranlarda ve global RSLT kalınlığında cerrahi sonrası istatistiksel anlamlı bir değişiklik saptanmadı (p>0.05). Sonuç: Kataraktlı gözlerde spektralis OKT kullanıldığında RSLT kalınlığı daha ince ölçülebilir. Bu nedenle, RSLT kalınlığı ölçümleri kataraktlı gözlerde dikkatli yorumlanmalıdır.

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Cite This Article

YILDIRIM, R., ÇAM, D., ARIKAN, G., GÜNENÇ, Ü. (2013). The effect of cataract on peripapillary retinal nerve fiber layer thickness measurements taken with spectral-domain optical coherence tomography. Glokom Katarakt, Cilt: 8 - Sayı: 4, 231–234. https://ajindex.com/articles/210888

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