Journals / KBB-Forum / 2019 / Cilt: 18 - Sayı: 2

THE SIGNIFICANCE OF SYSTEMIC INFLAMMATORY MARKERS IN THE DIFFERENTIAL DIAGNOSIS OF BENIGN AND MALIGN MASSES IN PATIENTS WITH PAROTID GLAND TUMORS

PAROTİS BEZİ TÜMÖRÜ OLAN HASTALARDA BENİGN VE MALİGN KİTLELERİN AYIRICI TANISINDA SİSTEMİK İNFLAMATUAR BELİRTEÇLERİN ÖNEMİ

Journal
KBB-Forum
Pages
101–106
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

But further studies are needed in this issue with a larger patient group

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: In this study, we aimed to evaluate the importance of neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR) and systemic inflammation index (SII) in the differential diagnosis of benign and malign masses in patients with parotid gland tumors.
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Key Findings & Data:Methods: Medical records of 134 patients, operated for parotid gland mass in our clinic between January 2017 and December 2018 examined retrospectively.
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Conclusion & Impact:But further studies are needed in this issue with a larger patient group
🔬Design:Research Article
📍Scope:2017 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: In this study, we aimed to evaluate the importance of neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR) and systemic inflammation index (SII) in the differential diagnosis of benign and malign masses in patients with parotid gland tumors. Methods: Medical records of 134 patients, operated for parotid gland mass in our clinic between January 2017 and December 2018 examined retrospectively. Patients were evaluated for age, sex, pre-operative complete blood count, post-operative histopathological diagnosis and presence of chronic disease. Patients were separated into 2 groups according to their post-operative histopathological diagnosis as benign tumors (group 1) and malignant tumors (group 2). Results: There was no statistically significant difference between the groups in terms of age and sex (p>0.05). Mean NLR and PLR were significantly higher in group 2 than with group 1 (p= 0.041 and p= 0.027; respectively). Although SII was higher in group 2, no statistically significant difference was found between the groups (p= 0.128). Conclusion: The NLR and PLR may be used to differential diagnosis of benign and malign masses in patients with parotid gland tumors. These parameters are inexpensive and easy to use. But further studies are needed in this issue with a larger patient group

Özet

Amaç: Bu çalışmada, parotis bezi tümörü olan hastalarda benign ve malign kitlelerin ayırıcı tanısında nötrofil-lenfosit oranı (NLO), platelet-lenfosit oranı (PLO) ve sistemik immün inflamasyon indeksinin (SII) önemini değerlendirmeyi amaçladık. Yöntemler: Ocak 2017-Aralık 2018 yılları arasında, parotis bezinde kitle nedeniyle opere edilen 134 hastanın klinik verileri retrospektif olarak incelendi. Hastalar yaş, cinsiyet, pre-operatif tam kan sayımı, post-operatif histopatolojik tanı ve kronik hastalık varlığı açısından değerlendirildi. Post-operatif histopatolojik tanısına göre benign (grup 1) ve malign (grup 2) tümörü olan hastalar olarak iki gruba ayrıldı. Bulgular: Gruplar arasında yaş ve cinsiyet açısından istatiksel olarak anlamlı bir fark yoktu (p>0.05). Ortalama NLO ve PLO değerleri, grup 2'de istatiksel olarak anlamlı derecede daha yüksekti (sırasıyla, p= 0.041 ve p= 0.027). Grup 2'de SII daha yüksek olmasına rağmen istatiksel olarak anlamlı değildi. Sonuç: Parotis bezi tümörü olan hastalarda benign ve malign kitlelerin ayırıcı tanısında, NLO ve PLO kullanılabilir. Bu parametreler ucuz ve kullanımı kolaydır. Ancak bu konuda, daha geniş bir hasta grubu ile yeni prospektif çalışmalara ihtiyaç vardır

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Cite This Article

EKİCİ, N. Y., KURAN, G. (2019). THE SIGNIFICANCE OF SYSTEMIC INFLAMMATORY MARKERS IN THE DIFFERENTIAL DIAGNOSIS OF BENIGN AND MALIGN MASSES IN PATIENTS WITH PAROTID GLAND TUMORS. KBB-Forum, Cilt: 18 - Sayı: 2, 101–106. https://ajindex.com/articles/209300

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