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Journals / İzmir Eğitim ve Araştırma Hastanesi Tıp Dergisi / 2019 / Cilt: 23 - Sayı: 1

RELATIONSHIPBETWEEN SMALL FOR GESTATIONAL AGE BABIES AND FIRST TRIMESTER SCREENING TEST MARKERS

GEBELİK YAŞINA GÖRE DÜŞÜK DOĞUM AĞIRLIKLI BEBEKLER İLE BİRİNCİ TRİMESTER TARAMA TESTİ BELİRTEÇLERİNİN İLİŞKİSİ

Ahkam Göksel KANMAZ
Adnan BUDAK
Pages
49–53
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion:First timester PAPP-A MoM value may be effective in predicting SGA pregnancies.

📌 3 Key Takeaways

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Objective & Hypothesis:Introduction: The prediction of small for gestational age (SGA) pregnancies with first trimester screening test predictors.
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Key Findings & Data:Material and Method: Between June 2014 and June 2016, 81 SGA pregnant women and 223 AGA pregnant women were compared in terms of demographic information, birth and neonatal outcomes.
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Conclusion & Impact:Conclusion:First timester PAPP-A MoM value may be effective in predicting SGA pregnancies.
🔬Design:Research Article
📍Scope:2014 Verileri
⚙️Variables:Domain Parameters

Abstract

Introduction: The prediction of small for gestational age (SGA) pregnancies with first trimester screening test predictors. Material and Method: Between June 2014 and June 2016, 81 SGA pregnant women and 223 AGA pregnant women were compared in terms of demographic information, birth and neonatal outcomes. At the same time, the values of nuchal translucency (NT), free beta-human chorionic gonadotropin (free BhCG) and pregnancyassociated plasma protein A (PAPP-A) MoM values of the first trimester screening test markers between two group was compared. Results: SGA groups were more frequently delivered by caesarean section from the control group pregnant, while control group wasmore frequently vaginally (p = 0.004). Newborn intensive care unit needs and stillbirth rates of infants of SGA group were found statistically significantly higher than control group (p <0.001 and p <0.001).NT and free BhCG MoM were not significantly different in the SGA and control groups, but in the SGA group the PAPP-A MoM value was significantly lower than the control group (p = 0.011). Conclusion:First timester PAPP-A MoM value may be effective in predicting SGA pregnancies.

Özet

Giriş: Birinci trimester tarama testi belirteçlerinin gebelik yaşına göre düşük doğum ağırlıklı bebek (small for gestational age (SGA)) doğurma ihtimali olan gebeleri öngörmedeki yeri incelenmiştir. Gereç ve Yöntem: 2014 Haziran-2016 Haziran tarihleri arasında doğum kilosu haftasında göre 10 persentilin altında olan 81 gebe ile 223 kontrol grubunu oluşturan gebe, demografik bilgileri, doğum ve neonatal sonuçları açısından karşılaştırıldı. Aynı zamanda her iki gruptaki gebelerin birinci trimester tarama testi belirteçlerinden olan ense kalınlığı (NT), serbest beta human koryonik gonadotropin (free BhCG) ve pregnancy-associated plasma protein A (PAPP-A)MoM değerleri karşılaştırıldı. Bulgular: SGA grubunda olan gebeler kontrol grubunda olan gebelere göre daha sık sezaryen ile doğum yaparken, kontrol grubundaki gebelerin doğum şekli daha sıklıkla vajinal idi (p=0,004). SGA grubundan olan gebelerin bebeklerinin yenidoğan yoğun bakım ihtiyacı ve ölü doğum oranı kontrol grubuna göre istatistiksel anlamlı olarak fazla saptandı (p<0,001 ve p<0,001). NT ve free BhCG MoMları açısından SGA ve kontrol grubundaki gebelerde farklılık saptanmazken, SGA grubundaki gebelerde istatistiki anlamlı olarak PAPP-A MoM değeri kontrol grubundaki gebelerden düşük saptandı(p=0,011). Sonuç:İlk trimester PAPP-A MoM değerinin düşüklüğü SGA gebeliklerini öngörmede etkili olabilir.

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Cite This Article

KANMAZ, A. G., BUDAK, A. (2019). RELATIONSHIPBETWEEN SMALL FOR GESTATIONAL AGE BABIES AND FIRST TRIMESTER SCREENING TEST MARKERS. İzmir Eğitim ve Araştırma Hastanesi Tıp Dergisi, Cilt: 23 - Sayı: 1, 49–53. https://ajindex.com/articles/207877

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