We discuss the diagnosis, treatment and the differential diagnosis of paranasal sinus involvement in Wegeners granulomatosis in the light of literature data.
📌 3 Key Takeaways
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Objective & Hypothesis:Wegeners granulomatosis which is rarely seen in children is an idiopathic necrotizing granulomatous vasculitis, affecting primarily paranasal sinuses, nasopharynx, lungs, kidneys and joints.
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Key Findings & Data:In this article, we report a very rare case of eight-year-old boy presenting with Wegeners granulomatosis of paranasal sinuses without lung, kidney and any other organ involvement.
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Conclusion & Impact:We discuss the diagnosis, treatment and the differential diagnosis of paranasal sinus involvement in Wegeners granulomatosis in the light of literature data.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters
Abstract
Wegeners granulomatosis which is rarely seen in children is an idiopathic necrotizing granulomatous vasculitis, affecting primarily paranasal sinuses, nasopharynx, lungs, kidneys and joints. In this article, we report a very rare case of eight-year-old boy presenting with Wegeners granulomatosis of paranasal sinuses without lung, kidney and any other organ involvement. We discuss the diagnosis, treatment and the differential diagnosis of paranasal sinus involvement in Wegeners granulomatosis in the light of literature data.
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Cite This Article
DAAR, G., CENGİZ, A. B., KARA, A., TOPALOĞLU, R., YÜCEL, Ö. T., DURSUN, İ. (2014). Wegener's granulomatosis presenting with an ısolated paranasal sinus ınvolvement in a child. art, Cilt: 29 - Sayı: 2, 130–133. https://ajindex.com/articles/204355
Wolff SM, Fauci AS, Horn RG, Dale DC. Wegeners granulomatosis. Ann Intern Med 1974;81:51325
Fauci AS, Haynes BF, Katz P, Wolff SM. Wegeners granulomatosis: prospective clinical and therapeutic experience with 85 patients for 21 years. Ann Intern Med 1983;98:7685
ODevaney K, Ferlito A, Hunter BC, Devaney SL, Rinaldo A. Wegeners granulomatosis of the head and neck. Ann Otol Rhinol Laryngol 1998;107:43945
Kornblut AD, Wolff SM, deFries HO, Fauci AS. Wegeners granulomatosis. Otolaryngol Clin North Am 1982;15:67383
Frosch M, Foell D. Wegener granulomatosis in childhood and adolescence. Eur J Pediatr 2004;163:42534
Miller ML, Pachman LM. Vasculitis syndromes. In: Behrman RE, Kliegman RM, Jenson HB, editors. Nelson Textbook of Pediatrics. 17th ed. Philadelphia: Saunders; 2004. p. 8301
Akikusa JD, Schneider R, Harvey EA, Hebert D, Thorner PS, Laxer RM, et al. Clinical features and outcome of pediatric Wegener's granulomatosis. Arthritis Rheum 2007;57:83744
Haliloglu M, Karcaaltincaba M, Toru M, Kiper N, Ariyurek MO. CT presentation of Wegeners granulomatosis in a child: rapidly progressive changes of pulmonary nodules to cavities. Eur J Radiol 2000;35:124
Simmons JT, Leavitt R, Kornblut AD, Fauci AS. CT of the paranasal sinuses and orbits in patients with Wegeners granulomatosis. Ear Nose Throat J 1987;66:13440
Levi M, Kodsi SR, Rubin SE, Lyons C, Golden R, Olitsky SE, et al. Ocular involvement as the initial manifestation of Wegener's granulomatosis in children. J AAPOS 2008;12:946
Lohrmann C, Uhl M, Warnatz K, Kotter E, Ghanem N, Langer M. Sinonasal computed tomography in patients with Wegener's granulomatosis. J Comput Assist Tomogr 2006;30:1225
Paling MR, Roberts RL, Fauci AS. Paranasal sinus obliteration in Wegener granulomatosis. Radiology 1982;144:53943
Singer J, Suchet I, Horwitz T. Paediatric Wegeners granulomatosis: two case histories and a review of the literature. Clin Radiol 1990;42:501.