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Journals / İzmir Tepecik Eğitim Hastanesi Dergisi / 2017 / Cilt: 27 - Sayı: 1

A harmless clinical condition presenting with dramatic elevation of alkaline phosphatase: Benign transient hyperphosphatasemia of childhood

Dramatik alkalen fosfataz yüksekliği ile seyreden zararsız bir klinik durum: Çocukluk çağı selim geçici hiperfosfatazemisi

Cahit Barış ERDUR
Cansu KAFES
Erhan ÖZBEK
Ferah GENEL
Pages
61–64
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In our case serum ALP values returned to normal levels within 3 weeks

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Benign transient hyperphosphatasemia of childhood is a harmless clinical condition without exactly determined etiology, characterized by 3-50-fold increase in serum alkaline phosphatase (ALP) levels, generally encountered in children under 5 years old.
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Key Findings & Data:However, clinicians and families may feel uneasy about this excessive increase.
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Conclusion & Impact:In our case serum ALP values returned to normal levels within 3 weeks
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Benign transient hyperphosphatasemia of childhood is a harmless clinical condition without exactly determined etiology, characterized by 3-50-fold increase in serum alkaline phosphatase (ALP) levels, generally encountered in children under 5 years old. Patients have no evidence of bone or liver disease. However, clinicians and families may feel uneasy about this excessive increase. Increased ALP values spontaneously return to normal levels within 2-6 months in most of the cases. In this report we present a 3,5 year-old boy with serum ALP levels rised up to 2679 IU/L, determined incidentally during an acute episode of gastroenteritis. In our case serum ALP values returned to normal levels within 3 weeks

Özet

Çocukluk çağı selim geçici hiperfosfatazemisi, genellikle 5 yaşın altındaki çocuklarda görülen, serum alkalen fosfataz (ALP) düzeyinin normalin 3-50 katı kadar yükseldiği, nedeni tam olarak bilinemeyen, zararsız bir klinik durumdur. Hastalarda kemik ve karaciğer hastalığı bulgusu yoktur. Ancak aşırı yükseklik klinisyenleri ve aileleri tedirgin edebilmektedir. Serum ALP düzeyleri olguların çoğunda 2-6 ay içerisinde kendiliğinden normale döner. Bu makalede akut gastroenterit atağı sırasında rastlantısal olarak serum ALP düzeyinin 2679 UI/L'ye kadar yükseldiği 3,5 yaşında bir erkek olgu sunuyoruz. Olgumuzda, serum ALP düzeyi üç hafta içerisinde normale döndü

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Cite This Article

ERDUR, C. B., KAFES, C., ÖZBEK, E., GENEL, F. (2017). A harmless clinical condition presenting with dramatic elevation of alkaline phosphatase: Benign transient hyperphosphatasemia of childhood. İzmir Tepecik Eğitim Hastanesi Dergisi, Cilt: 27 - Sayı: 1, 61–64. https://ajindex.com/articles/203734

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