Journals / JAREM / 2017 / Cilt: 7 - Sayı: 2

Anaphylaxis Development after Intravenous Injection of Cow's Milk

İnek Sütünün İntravenöz Enjeksiyonu Sonrası Gelişen Anafilaksi

Journal
JAREM
Pages
95–98
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Although sepsis and septic shock development is usually expected after the injection of foreign substances such as in this case, interestingly, there was an anaphylactic reaction caused by the patient's subclinical cow's milk allergy.

📌 3 Key Takeaways

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Objective & Hypothesis:Although rare, intravenous injection of foreign substances during childhood can cause fatal complications.
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Key Findings & Data:In this report, we discuss the clinical presentation and treatment of a 17-year-old nursing student who injected pasteurized homogenized cow's milk into herself due to curiosity.
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Conclusion & Impact:Although sepsis and septic shock development is usually expected after the injection of foreign substances such as in this case, interestingly, there was an anaphylactic reaction caused by the patient's subclinical cow's milk allergy.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Although rare, intravenous injection of foreign substances during childhood can cause fatal complications. Most of the cases reported in the literature are accidental intravenous administrations of enteral feeding formulas. To the best of our knowledge, this is the first case of intravenous injection of cow's milk. In this report, we discuss the clinical presentation and treatment of a 17-year-old nursing student who injected pasteurized homogenized cow's milk into herself due to curiosity. The girl presented to our emergency department after this injection. During admission, she presented with angioedema, gastrointestinal symptoms, dyspnea, and tachycardia associated with resistant hypotension. She, then, developed leukocytosis and elevated D-dimer levels, as determined in the laboratory. The patient was diagnosed as having anaphylaxis with clinical presentation and cow's milk-specific IgE positivity, based on laboratory findings. The patient was initially treated with adrenaline, corticosteroids, and antihistamines. Inotropes including catecholamines and wide-spectrum antibiotics were added into the therapy for resistant hypotension and sepsis prophylaxis. Low-molecularweight heparin treatment was given for the elevated D-dimer levels and prevention of embolic events. With these therapeutic interventions, there were no signs of sepsis, thrombosis, embolus, and multi-organ failure. The patient was discharged without any neurological complications or sequelae on the 6th day of hospital admission. Although sepsis and septic shock development is usually expected after the injection of foreign substances such as in this case, interestingly, there was an anaphylactic reaction caused by the patient's subclinical cow's milk allergy.

Özet

Çocuklukta nadir olmasına rağmen, yabancı cisimlerin damar içinden verilmesi ölümcül komplikasyonlara yol açabilir. Literatürde bildirilen çoğu olgu enteral beslenme formülalarının kazayla damar içinden verilmesi sonucudur. Bildiğimiz kadarıyla, olgumuz inek sütünün damar içinden yapıldığı ilk vakadır. Bu olgu sunumunda, 17 yaşında kız hemşirelik öğrencisinin, sonucunu merak etmesi nedeni ile kendisine intravenöz pastörize ve homojenize inek sütü enjekte etmesi sonrasında gelişen klinik tablo ve tedavisini tartışmaktayız. 17 yaşında kız inek sütünü damardan kendine enjekte etmesi sonrasında acil birimimize getirildi. Yatışında; anjioödem, gastrointestinal şikâyetler, dispne, taşikardi ve beraberinde dirençli tansiyon düşüklüğü mevcuttu. Daha sonra laboratuar bulgularında, lökositoz ve D-dimer yüksekliği gelişti. Hastamızın klinik görünümü ve laboratuar bulgularında inek sütü spesifik IgE pozitifliği ile anafilaksi geçirdiği teşhis edildi. Olgumuza başlangıçta adrenalin, kortikosteroid ve antihistaminik tedavisi uygulanmıştır. Katekolamin dâhil inotrop ilaçlar ve geniş spektrumlu antibiyotikler dirençli tansiyon düşüklüğü ve sepsis profilaksisi için tedaviye eklendi. Yüksek D-dimer düzeyi ve embolik olayların önlenmesi için, düşük moleküler ağırlıklı heparin tedavisi verildi. Tedaviye yönelik girişimler sonrasında, sepsis, tromboz, emboli ve multi-organ yetmezliğine ait belirtiler gelişmedi. Hastaneye yatışının altıncı gününde, olgu nörolojik komplikasyonsuz ve sekelsiz olarak taburcu edildi. Bu tür bir girişim sonrası normalde sepsis ve septik şok gibi bir tablonun gelişmesi beklenirken, hastamızda daha önceden mevcut olan ancak fark edilmeyen, hafif inek sütü duyarlılığına bağlı anafilâksi tablosunun gelişmesi şaşırtıcı olmuştur.

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Cite This Article

ELMAS, B., ÖZDEMİR, Ö., BİNGÖL, D. A. (2017). Anaphylaxis Development after Intravenous Injection of Cow's Milk. JAREM, Cilt: 7 - Sayı: 2, 95–98. https://ajindex.com/articles/201710

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