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Journals / Glokom Katarakt / 2015 / Cilt: 10 - Sayı: 2

The Effects of Collagen Cross-Linking on Intraocular Pressure and Central Corneal Thickness

Kollajen Çapraz Bağlamanın Göz İçi Basıncı ve Merkezi Kornea Kalınlığı Üzerine Etkisi

Mehmet Özgür ZENGİN
Esat ÇINAR
Aslı ÇELİK
Cem KÜÇÜKERDÖNMEZ
Pages
100–102
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

This may be due to the increased stiffness of the treated cornea

📌 3 Key Takeaways

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Objective & Hypothesis:Purpose: To investigate the effect of corneal collagen cross-linking (CCL) on central corneal thickness (CCT) and intraocular pressure (IOP).
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Key Findings & Data:Materials and Methods: CCL with 0.1% riboflavin solution and 30 min of ultraviolet A radiation was performed on the right eyes of 20 New Zealand albino adult rabbits (2.4-3.2 kg), (20 eyes).
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Conclusion & Impact:This may be due to the increased stiffness of the treated cornea
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Purpose: To investigate the effect of corneal collagen cross-linking (CCL) on central corneal thickness (CCT) and intraocular pressure (IOP). Materials and Methods: CCL with 0.1% riboflavin solution and 30 min of ultraviolet A radiation was performed on the right eyes of 20 New Zealand albino adult rabbits (2.4-3.2 kg), (20 eyes). The left eyes served as control. IOP was measured using Tonopen hand-held device (corneal applanation tonometer) and CCT by the pachymeter (Accutome, AccuPachV pachymeter, USA) before treatment and weekly for one month following CCL. Results: Before CCL, IOP readings and CCT measurements were similar between the two eyes (p>0.05). Following CCL treatment, the mean IOP was found significantly higher in the treatment group, however, mean CCT was not significantly different between the groups. (0.005<p<0.03). Conclusions: Measuring IOP by tonopen yielded overestimated IOP results following CCL. This may be due to the increased stiffness of the treated cornea

Özet

Amaç: Kollajen çapraz bağlamanın (KÇB) göz içi basıncı(GİB) ve merkezi kornea kalınlığı (MKK) üzerine etkisinin araştırılması. Gereç ve Yöntem: Yeni Zelanda cinsi toplam 20 albino tavşanın (2.4-3.2 kg) sağ gözlerine (20 göz) %0.1 riboflavin solüsyon ve 30 dakika ultraviyole A ışını uygulanarak KÇB işlemi yapıldı. Sol gözler kontrol grubu olarak alındı. GİB değerleri Tonopen XL (Medtronic, Jacksonville, Florida, USA) kulanılarak, MKK pakimetri (Accutome, AccuPachV pachymeter, USA) kullanılarak tedavi öncesi ve tedavi sonrası haftalık olmak üzere 1 ay boyunca ölçüldü. Bulgular: KÇB öncesi, IOP ve MKK ölçümleri iki göz arasında benzer saptandı (p>0.05). KÇB’yi takiben, ortalama GİB ölçümleri tedavi edilen gözlerde anlamlı oranda yüksek saptanırken, MKK ölçümleri gruplar arasında anlamlı farklılık göstermedi (p>0.05). Sonuç: KÇB sonrası tonopen ile ölçülen GİB değerleri normalden yüksek bulunmuştur. Tedavi edilen korneada artmış rijiditenin buna sebep olabileceği düşünülmektedir.

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Cite This Article

ZENGİN, M. Ö., ÇINAR, E., ÇELİK, A., KÜÇÜKERDÖNMEZ, C. (2015). The Effects of Collagen Cross-Linking on Intraocular Pressure and Central Corneal Thickness. Glokom Katarakt, Cilt: 10 - Sayı: 2, 100–102. https://ajindex.com/articles/201619

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