Journals / Düşünen Adam - Psikiyatri ve Nörolojik Bilimler Dergisi / 2015 / Cilt: 28 - Sayı: 4

Venlafaxine-induced acute dystonia: a case report

Venlafaksin kullanımına bağlı akut distoni: Olgu sunumu

Pages
374–377
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

This case is presented to emphasize that the occurrence of extrapyramidal symptoms, which are clinically important side effects requiring intervention, may be related with venlafaxine, a serotonin noradrenaline reuptake inhibitor

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Although mechanisms underlying neuroleptic-induced extrapyramidal symptoms have been well researched, extrapyramidal symptoms associated with antidepressants are understudied.
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Key Findings & Data:Recognized risk factors for extrapyramidal symptoms associated with antidepressants are advancing age, female sex, and pharmacokinetic interaction of concurrently used drugs with CYP2D6 inhibition effect.
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Conclusion & Impact:This case is presented to emphasize that the occurrence of extrapyramidal symptoms, which are clinically important side effects requiring intervention, may be related with venlafaxine, a serotonin noradrenaline reuptake inhibitor
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Although mechanisms underlying neuroleptic-induced extrapyramidal symptoms have been well researched, extrapyramidal symptoms associated with antidepressants are understudied. Research conducted to date is more concerned with selective serotonin reuptake inhibitors. Recognized risk factors for extrapyramidal symptoms associated with antidepressants are advancing age, female sex, and pharmacokinetic interaction of concurrently used drugs with CYP2D6 inhibition effect. This case is presented to emphasize that the occurrence of extrapyramidal symptoms, which are clinically important side effects requiring intervention, may be related with venlafaxine, a serotonin noradrenaline reuptake inhibitor

Özet

Antipsikotiklere bağlı ekstrapiramidal sendromlar iyi araştırılmış olmasına rağmen, antidepresanlara bağlı ekstrapiramidal sendromlar yeterince incelenmemiştir. Bugüne kadar yapılan araştırmalar daha çok Seçici Serotonin Gerialım İnhibitörleri ile ilgilidir. Antidepresan kullanımına bağlı ekstrapiramidal sendrom gelişimi için tanımlanmış risk faktörleri ileri yaş, kadın cinsiyet ve eş zamanlı kullanılan ilaçların CYP2D6 inhibisyonu etkileşimidir. Bu olgu klinik olarak son derece önemli ve müdahale gerektiren bir yan etki olan ekstrapiramidal sendromun, venlafaksin gibi bir Serotonin Noradrenalin Gerialım İnhibitörüne bağlı olarak da gelişebileceğini vurgulamak amacıyla sunulmuştur

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Cite This Article

SÖNMEZ, İ., KÖŞGER, F. (2015). Venlafaxine-induced acute dystonia: a case report. Düşünen Adam - Psikiyatri ve Nörolojik Bilimler Dergisi, Cilt: 28 - Sayı: 4, 374–377. https://ajindex.com/articles/201294

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References (6)

  1. Madhusoodanan S, Alexeenko L, Sanders R, Brenner R. Extrapyramidal symptoms associated with antidepressants: a review of the literature and an analysis of spontaneous reports. Ann Clin Psychiatry 2010; 22:148-156
  2. Foster AR, Lancaster NP. Disturbance of motor function during treatment with imipramine. Br Med J 1959; 2:1452-1453. [CrossRef] 3. Gill HS, DeVane CL, Risch SC. Extrapyramidal symptoms associated with cyclic antidepressant treatment: a review of the literature and consolidating hypotheses. J Clin Psychopharmacol 1997; 17:377-389. [CrossRef] 4. Schillevoort I, Van Puijenbroek EP, de Boer A, Roos RA, Jansen PA, Leufkens HG. Extrapyramidal syndromes associated with selective serotonin reuptake inhibitors: a case-control study using spontaneous reports. Int Clin Psychopharmacol 2002; 17:75-79. [CrossRef] 5. Kapur S, Remington G. Serotonin-dopamine interaction and its relevance to schizophrenia. Am J Psychiatry 1996; 153:466-476. [CrossRef] 6. Coulter DM, Pillans PI. Fluoxetine and extrapyramidal side effects. Am J Psychiatry 1995; 152:122-125. [CrossRef] 7. Leo RJ. Movement disorders associated with the serotonin selective reuptake inhibitors. J Clin Psychiatry 1996; 57:449-454. [CrossRef] 8. Venlafaxine and extrapyramidal effects. http://www.lareb.nl/ LarebCorporateWebsite/media/publicaties/kwb_2004_2_venla. pdf. Accessed February 20, 2015
  3. Caley CF. Extrapyramidal reactions and the selective serotoninreuptake inhibitors. Ann Pharmacother 1997; 31:1481-1489
  4. Gerber PE, Lynd LD. Selective serotonin-reuptake inhibitorinduced movement disorders. Ann Pharmacother 1998; 32:692- 698. [CrossRef] 11. Hisli N. Validity and reliability of Beck Depression Inventory for university students. Journal of Psychology 1989; 7:3-13. (Turkish
  5. World Health Organization. ICD-10 Classification of Mental and Behavioural Disorders: Clinical Descriptions and Diagnostic Guidelines. Ozturk MO, Ulug B (Translation Editors) First ed, Ankara: Turkiye Sinir ve Ruh Sagligi Dernegi, 1993. (Turkish
  6. Naranjo CA, Busto U, Sellers EM, Sandor P, Ruiz I, Roberts EA, Janecek E, Domecq C, Greenblatt DJ. A method for estimating the probability of adverse drug reactions. Clin Pharmacol Ther 1981; 30:239-245. [CrossRef] 14. Fonseca L, Rodrigues M, Machado A. Psychogenic movement disorder after a venlafaxine-induced dystonia. Mov Disord 2010; 25:506-507. [CrossRef] 15. Ng J, Sansone RA, McDonald S. Akathisia and abnormal movements of the upper extremities with venlafaxine