Journals / Eastern Journal of Medicine / 2018 / Cilt: 23 - Sayı: 2

Genetics of premature ovarian failure

Pages
135–140
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this article, recent literature on premature ovarian failure attempted to reveal current genetic etiology of premature ovarian failure.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Premature ovarian failure was defined as the cut-off of menstrual period for at least 4-6 months before 40 years of age, and FSH values measured over a month were over 40 IU/L.
📊
Key Findings & Data:Although etiology is not fully understood, it is thought that genetic, immunological and environmental factors can play a role.
💡
Conclusion & Impact:In this article, recent literature on premature ovarian failure attempted to reveal current genetic etiology of premature ovarian failure.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Premature ovarian failure was defined as the cut-off of menstrual period for at least 4-6 months before 40 years of age, and FSH values measured over a month were over 40 IU/L. Although etiology is not fully understood, it is thought that genetic, immunological and environmental factors can play a role. Nowadays, translational and deletion in the critical regions on the X chromosome are defined in the developmental light in the genetic area. New approaches have been developed in clinical follow-up and treatment in recent years. It has been reported that caution should be taken in the follow-up, especially in terms of osteoporosis. In this article, recent literature on premature ovarian failure attempted to reveal current genetic etiology of premature ovarian failure.

🔖

Cite This Article

TOLUNAY, H. E., BOZA, B., VARLI, B. (2018). Genetics of premature ovarian failure. Eastern Journal of Medicine, Cilt: 23 - Sayı: 2, 135–140. https://ajindex.com/articles/200142

References (19)

  1. Albright F, Smith PH, Fraser R. A syndrome characterized by primary ovarian insuficiency and decreased stature. Am J Med Sci 1942; 204: 625-648
  2. Cooper AR, Baker VL, Streling EW, Ryan ME, Woodruff TK, Nelson LM. The time is now for a new approach to primary ovarian insufficiency. Fertile Sterile 2011; 95: 1890- 1897
  3. Kalantaridou SN, Nelson LM. Premature ovarian failure is not premature menopause. Ann NY Acad Sci 2000; 900: 393-402
  4. Rebar RW, Connoly HV. Clinical features of women with hypergonadotropic amenorrhea. Fertile Sterile 1990; 53: 804-810
  5. Alper MM, Jolly EE, Garner PR. Pregnancies after premature ovarian failure. Obstet Gynecol 1986; 67: 59-62
  6. Rebar RW. Premature ovarian failure. Obstet Gynecol 2009; 113: 1355-1363
  7. Welt CK. Primary ovarian insufficiency: a more accurate term for premature ovarian failure. Clin endocrinol (Oxf) 2008; 68: 499-509
  8. De Vos M, Devroey P, Fauser B. Primary ovarian insuffiency. Lancet 2010; 376: 911-923
  9. Panay N, Kalu E. Management of premature ovarian failure. Best pract Res Clin Obstet Gynaecol 2009; 23: 129-140
  10. Anasti JN. Premature ovarian failure: an update. Fertile Steril 1998; 70: 1-15
  11. Coulam CB, Adamson SC, Annegers JF. Incidence of premature ovarian failure. Obstet Gynecol 1986; 67: 604-606
  12. Luborsky JL, Meyer P, Sowers MF, Gold EB, Santoro N. Premature menopause in a multiethnic population study of the menopause transition. Hum Reprod 2002; 18: 199-206
  13. Chang SH, Kim CS, Lee KS, et al. Premenopausal factors influencing premature ovarian failure and early menopause. Maturitas 2007; 58: 19-30
  14. Goswami D, Conway GS. Premature ovarian failure. Hum Reprod Update 2005; 11: 391-410
  15. Persani L, Rossetti R, Cacciatore C. Genes involved in human premature ovarian failure. J Mol Endocrinol 2010; 45: 257-279
  16. Reindollar RH. Turner syndrome: Contemporary thoughts and reproductive issues. Semin Reprod Med 2011; 29: 342-352
  17. Wittenberger MD, Hagerman RJ, Sherman SL, et al. The FMR1 premutation and reproduction. Fertil Sterile 2007; 87: 456-465
  18. American College of Medical Genetics. Technical standards and guidelines for fragile X testing: a revision to the disease specific supplements to the Standards and Guidelines for Clinical Genetics Laboratories of the American College of Medical Genetics. Bethesda (MD): ACMG; 2005. Available at: http://www.acmg.net/Pages/ACGM_Activities /stds-2002/ fx.htm
  19. Kronquist KE, Sherman SL, Spector EB. Clinical significance