Journals / Flora İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi / 2016 / Cilt: 21 - Sayı: 2

A Rare Pulmonary Infection Case: Pulmonary Actinomycosis

Nadir Bir Akciğer İnfeksiyonu Olgusu: Pulmoner Aktinomikoz

Pages
88–92
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Patients with infiltrations on chest radiography and with no response to antibiotic treatment should not be forgotten to be examined for tuberculosis, lung cancer and rarely seen Actinomycosis infection for distinctive diagnosis.

📌 3 Key Takeaways

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Objective & Hypothesis:Actinomycosis is a slowly progressive disease which is caused by gram-positive anaerobic bacteria of the family Actinomyceataceae.
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Key Findings & Data:A 57-year-old male patient presented with ongoing sputum and dyspnea.
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Conclusion & Impact:Patients with infiltrations on chest radiography and with no response to antibiotic treatment should not be forgotten to be examined for tuberculosis, lung cancer and rarely seen Actinomycosis infection for distinctive diagnosis.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Actinomycosis is a slowly progressive disease which is caused by gram-positive anaerobic bacteria of the family Actinomyceataceae. Actinomycesisraelii is the most common agent of actinomycosis. Pulmonary actinomycosis clinically or radiologically imitates tuberculosis, pulmonary abscess or lung cancer. These similarities principally lead to misdiagnosis or delayed diagnosis. Predisposing factors which emanate the illness include alcoholism, bad-oral hygiene, gingiva diseases, face traumata, diabetes mellitus, emphysema, chronic bronchitis, and bronchiectasis. A 57-year-old male patient presented with ongoing sputum and dyspnea. The non-smoker patient’s physical examination indicated that right central and sub-regional lung had rales. Whole blood values and pulmonary function test were normal. On chest X-Ray, there was a nonhomogeneous density beat on the right lower zone. The patient who did not respond to non-specific antibiotic treatment given in two weeks and tuberculosis and lung cancer was evaluated with bronchoscopy. Pathological examination showed actinomyces colonies, squamous cells, lymphocytes, macrophages, and neutrophils. Oral amoxicillin was started after IV ampicillin/sulbactam treatment . In the 6th month of treatment, the symptoms of the patient and radiologic findings receded. Patients with infiltrations on chest radiography and with no response to antibiotic treatment should not be forgotten to be examined for tuberculosis, lung cancer and rarely seen Actinomycosis infection for distinctive diagnosis.

Özet

Aktinomikoz Actinomyceataceae familyasındaki gram-pozitif anaerop bakterilerin neden olduğu yavaş seyirli bir hastalıktır. Actinomyces israelii en sık karşılaşılan ajandır. Pulmoner aktinomikoz klinik ve radyolojik olarak tüberküloz, akciğer apsesi veya akciğer kanserini taklit eder. Bu benzerlikler genellikle yanlış tanıya ya da tanıda gecikmeye neden olur. Hastalığa predispozan faktörler arasında alkolizm, kötü ağız hijyeni, diş eti hastalıkları ve cerrahisi, yüz travması, diabetes mellitus, amfizem, kronik bronşit ve bronşektazi vardır. Tedavide ilk tercih antibiyotik yüksek doz penisilinlerdir. Bir yıldır devam eden balgam ve nefes darlığı şikayeti ile 57 yaşında erkek hasta tarafımıza başvurdu. Sigara kullanmayan hastanın fizik muayenesinde sağ akciğer orta ve alt bölgede ralleri mevcuttu. Kan değerleri, solunum fonksiyon testi normaldi. Akciğer grafisinde sağ alt zonda nonhomojen dansite atışı mevcuttu. İki hafta süreyle verilen nonspesifik antibiyotik tedavisine yanıt vermeyen hastaya tüberküloz, akciğer malignitesi ön tanılarıyla bronkoskopi yapıldı. Patoloji sonucunda aktinomiçes kolonileri, skuamöz hücre, lenfositler, histiyositler, nötrofiller izlendi. Hastaya intravenöz ampisilin-sulbaktam tedavisi başlandı. Bir ay sonunda tedaviye oral amoksisilin ile devam edildi. Tedavinin altıncı ayında bulunan hastanın semptomları ve radyolojik bulguları geriledi. Akciğer grafisinde antibiyotik tedavisine yanıt vermeyen infiltratif görünümü olan hastalarda tübeküloz, akciğer kanseri gibi ayırıcı tanılar arasında nadir görülen aktinomikoz infeksiyonu da unutulmamalıdır

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Cite This Article

GÜLHAN, M., GÜLHAN, P. Y., ARSLAN, M., YILDIZ, Ş. (2016). A Rare Pulmonary Infection Case: Pulmonary Actinomycosis. Flora İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi, Cilt: 21 - Sayı: 2, 88–92. https://ajindex.com/articles/199123

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