Journals / art / 2015 / Cilt: 30 - Sayı: 4

Increased Carotid Intima-Media Thickness in Female Patients With Fibromyalgia: A Preliminary Study

Journal
art
Pages
307–310
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Our finding may have stemmed from endothelial dysfunction possibly due to increased sympathetic activity.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objectives: This study aims to measure the carotid artery intima-media thickness (IMT) of patients with fibromyalgia (FM) by using ultrasound imaging and to investigate whether carotid IMT measurements were associated with the severity of FM.
📊
Key Findings & Data:Patients and methods: Nineteen female patients (mean age 42.9±8.1 years; range 24 to 57 years) and 17 healthy female subjects (mean age 41.5±6.3 years; range 33 to 57 years) were included in this study.
💡
Conclusion & Impact:Our finding may have stemmed from endothelial dysfunction possibly due to increased sympathetic activity.
🔬Design:Survey & Empirical Study
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objectives: This study aims to measure the carotid artery intima-media thickness (IMT) of patients with fibromyalgia (FM) by using ultrasound imaging and to investigate whether carotid IMT measurements were associated with the severity of FM. Patients and methods: Nineteen female patients (mean age 42.9±8.1 years; range 24 to 57 years) and 17 healthy female subjects (mean age 41.5±6.3 years; range 33 to 57 years) were included in this study. The Fibromyalgia Impact Questionnaire was used to determine the severity of FM. After clinical evaluation of the subjects, ultrasound imaging examinations of the carotid IMT were performed. Results: Right and left carotid IMT values were thicker in the patient group in comparison to the control group (p1=0.05, p2=0.03, respectively). Carotid IMT values were correlated with age and body mass index. Carotid IMT values did not have any correlation with blood glucose levels, creatinine levels, serum lipid profile and Fibromyalgia Impact Questionnaire scores in FM patients. Conclusion: Carotid IMT of FM patients seems to be affected. Our finding may have stemmed from endothelial dysfunction possibly due to increased sympathetic activity.

🔖

Cite This Article

BÖLÜK, H., ÖZTÜRK, G. T., CÖMERT, D., ERSÖZ, M. (2015). Increased Carotid Intima-Media Thickness in Female Patients With Fibromyalgia: A Preliminary Study. art, Cilt: 30 - Sayı: 4, 307–310. https://ajindex.com/articles/198403

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (14)

  1. Wolfe F, Smythe HA, Yunus MB, Bennett RM, Bombardier C, Goldenberg DL, et al. The American College of Rheumatology 1990 Criteria for the Classification of Fibromyalgia. Report of the Multicenter Criteria Committee. Arthritis Rheum 1990;33:160-72
  2. Ünübol A, Bozba¤ GT, Ünübol M, Gürer G. An evaluation of mean platelet volume and serum lipid profile in patients with fibromyalgia syndrome. Arch Rheumatol 2013;28:251-5
  3. Wolfe F, Ross K, Anderson J, Russell IJ, Hebert L. The prevalence and characteristics of fibromyalgia in the general population. Arthritis Rheum 1995;38:19-28
  4. Bradley LA. Pathophysiology of fibromyalgia. Am J Med 2009;122:22-30
  5. McCarberg B, Barkin RL, Wright JA, Cronan TA, Groessl E, Schmidt SM. Tender points as predictors of distress and the pharmacologic management of fibromyalgia syndrome. Am J Ther 2003;10:176-92
  6. Giske L, Vøllestad NK, Mengshoel AM, Jensen J, Knardahl S, Røe C. Attenuated adrenergic responses to exercise in women with fibromyalgia--a controlled study. Eur J Pain 2008;12:351-60
  7. Martinez-Lavin M. Biology and therapy of fibromyalgia. Stress, the stress response system, and fibromyalgia. Arthritis Res Ther 2007;9:216
  8. Halilo¤lu S, Carlioglu A, Sahiner E, Karaaslan Y, Kosar A. Mean platelet volume in patients with fibromyalgia. Z Rheumatol 2014;73:742-5
  9. Inal S, ‹nal EE, Okyay GU, Öztürk GT, Öneç K, Güz G. Fibromyalgia and nondipper circadian blood pressure variability. J Clin Rheumatol 2014;20:422-6
  10. Martínez-Lavín M, Hermosillo AG, Rosas M, Soto ME. Circadian studies of autonomic nervous balance in patients with fibromyalgia: a heart rate variability analysis. Arthritis Rheum 1998;41:1966-71
  11. Cohen H, Neumann L, Shore M, Amir M, Cassuto Y, Buskila D. Autonomic dysfunction in patients with fibromyalgia: application of power spectral analysis of heart rate variability. Semin Arthritis Rheum 2000;29:217-27
  12. Lee JH, Cho KI, Kim SM, Lee HG, Kim TI. Arterial stiffness in female patients with fibromyalgia and its relationship to chronic emotional and physical stress. Korean Circ J 2011;41:596-602
  13. Karao¤lan B, Öztürk GT, Özdo¤an V, Cumao¤lu A, Oktar S, Ta N, et al. Investigation of the correlation between ADMA levels and carotid artery intima-media thickness in rheumatoid arthritis patients. Turk J Phys Med Rehab 2011;57:114-8
  14. Lorenz MW, Markus HS, Bots ML, Rosvall M, Sitzer M. Prediction of clinical cardiovascular events with carotid intima-media thickness: a systematic review and