Journals / KBB-Forum / 2017 / Cilt: 16 - Sayı: 3

THE EVALUATION OF THE PROGNOSTIC SIGNIFICANCE OF TUMOR BUDDING IN PAROTID MUCOEPIDERMOID CARCINOMA

PAROTİS BEZİNİN MUKOEPİDERMOİD KARSİNOMLARINDA TÜMÖR TOMURCUKLANMASININ PROGNOSTİK ÖNEMİNİN DEĞERLENDİRİLMESİ

Journal
KBB-Forum
Pages
70–75
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In such cases the prognosis of mucoepidermoid cancer may be affected negatively.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: In our study we aimed at researching on tumor budding and its effect on the other pathologic factors in parotid gland mucoepidermoid cancers.
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Key Findings & Data:Methods: We included in the study a total of 20 patients diagnosed with parotid gland mucoepidermoid carcinoma from 2006 to 2016.
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Conclusion & Impact:In such cases the prognosis of mucoepidermoid cancer may be affected negatively.
🔬Design:Research Article
📍Scope:2006 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: In our study we aimed at researching on tumor budding and its effect on the other pathologic factors in parotid gland mucoepidermoid cancers. Methods: We included in the study a total of 20 patients diagnosed with parotid gland mucoepidermoid carcinoma from 2006 to 2016. The files of the patients included into the study were examined. The patients’ pathologic tissue cross-sections were retrieved from the archives and evaluated for tumor budding. Results: There was no statistically significant relationship between tumor budding and age, sex, perineural invasion, extracapsular extension, pathologic lymph node, and pathologic tumor stage (p>0.05).Whereas there was a statistically significant relationship between tumor budding and tumor grade and lymphovascular invasion (p 0.05). Conclusion: Lymphovascular invasion and high tumor grade may be seen in cases of mucoepidermoid carsinoma with more than five tumor buddings. In such cases the prognosis of mucoepidermoid cancer may be affected negatively.

Özet

Amaç: Biz çalışmamızda parotis mukoepidermoid kanserlerinde tümör tomurcuklanmasını ve onun diğer prognostik faktörlerle olan ilişkisini araştırmayı amaçladık. Gereç ve yöntem: Parotis bezi mukoepidermoid karsinomu teşhisiyle 2006 ile 2016 yılları arasında tedavi edilen toplam 20 hasta çalışmaya dâhil edildi. Çalışmaya dâhil edilen hastaların dosyaları incelendi. Hastaların patolojik doku kesitleri arşivden bulunarak tümör tomurcuklanması açısından değerlendirildi. Bulgular: Tümör tomurcuklanması istastistiksel olarak yaş, cinsiyet, perinöral invazyon, ekstrakapsüler yayılım, patolojik lenf bezi ve patolojik tümör evresi ile karşılaştırıldığında aralarında anlamlı bir ilişki yoktu (p>0.05). Tümör tomurcuklanması istatistiksel olarak tümör derecesi ve lenfovasküler invazyon ile karşılaştırıldığında aralarında anlamlı bir ilişki vardı (p 0.05). Sonuçlar: Tümör tomurcuklamasının sayısı beşten fazla olan parotis mukoepidermoid kanserli olgularda lenfovasküler invazyon ve yüksek tümör derecesi görülebilir. Bu durumda mukoepidermoid kanserli olgularda prognozu olumsuz etkileyebilir.

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Cite This Article

ARICIGİL, M., OLTULU, P., GÖNÜL, Y., AYDEMİR, F. (2017). THE EVALUATION OF THE PROGNOSTIC SIGNIFICANCE OF TUMOR BUDDING IN PAROTID MUCOEPIDERMOID CARCINOMA. KBB-Forum, Cilt: 16 - Sayı: 3, 70–75. https://ajindex.com/articles/197799

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