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Journals / GORM:Gynecology Obstetrics & Reproductive Medicine / 2015 / Cilt: 21 - Sayı: 3

Ovülasyon İndüksiyonu ve İntrauterin İnseminasyon Sonucu Oluşan Parsiyel Molar ve İkiz Gebelik Kombinasyonu

Triplet Pregnancy with Partial Hydatidiform Mole Coexisting with Two Fetuses after Ovulation Induction and Intrauterine Insemination

Mehmet Serdar KÜTÜK
MEHMET DOLANBAY
Hilal AKALIN
Mahmut Tuncay ÖZGÜN
Turhan ÖKTEM
Munis DÜNDAR
Ercan AYGEN
Pages
171–173
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

These patients shouldbe carefully followed after the pregnancy for persistent trophoblastic disease

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Partial hydatidiform mole with dichorionic twin fetuses is extremely rare condition, and only three caseshave been reported before.
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Key Findings & Data:The fetus B with molar placenta has been selectively terminated at 11thweeksand the pregnancy was complicated with preeclampsia, hyperthyroidism, and culminated in spontaneous abortion at 20thweeks.
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Conclusion & Impact:These patients shouldbe carefully followed after the pregnancy for persistent trophoblastic disease
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Partial hydatidiform mole with dichorionic twin fetuses is extremely rare condition, and only three caseshave been reported before. Twenty- five years old primigravida having a trizygotic triplet pregnancy thathas been conceived by ovulation induction and intrauterine insemination was referred to our departmentfor threatened abortion. The fetus B with molar placenta has been selectively terminated at 11thweeksand the pregnancy was complicated with preeclampsia, hyperthyroidism, and culminated in spontaneous abortion at 20thweeks. After the abortion, the pathologic evaluation suggested partial mole, andgenetic evaluation confirmed the diagnosis. The postpartum course complicated with persistent trophoblastic disease that well responded to four course of methotrexate therapy. The optimal management of partial hydatidiform mole coexistent with two fetuses is currently uncertain. The choice of continuing the pregnancy must be individualized, depending on the patient condition. These patients shouldbe carefully followed after the pregnancy for persistent trophoblastic disease

Özet

Dikoryonik ikiz gebelikle birlikte parsiyel mol hidatiform oldukçanadir görülür ve bu vakadan önce yalnızca üç vaka bildirilmiştir.Yirmi beş yaşında primigravid hasta ovulasyon indüksiyonu veintrauterin inseminasyon ile elde edilmiş trizigotik üçüz gebelikve düşük tehdidi tanılarıyla kliniğimize kabul edildi. Molar plasentaya sahip fetus B gebeliğin 11. haftasında selektif sonlandırıldı ve arkasından gebelik preeklampsi, hipertiroidizm ilekomp like olarak 20. gebelik haftasında spontane düşükle sonlandı. Düşük sonrası patolojik inceleme parsiyel molü destekleyince genetik inceleme ile tanı doğrulandı. Doğum sonrası dönem dört doz metotreksat tedavisine iyi cevap alınan persistantrofoblastik hastalık ile komplike oldu. İki fetus ile birlikte gelişenparsiyel mol hidatiform olgularına yaklaşım henüz net değildir.Gebeliğin devam seçeneği hastanın durumu gözetilerek bireyselleştirilebilir. Gebelik sonrası hastalar persistan trofoblastikhastalık açısından mutlaka yakın takip edilmelidir

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Cite This Article

KÜTÜK, M. S., DOLANBAY, M., AKALIN, H., ÖZGÜN, M. T., ÖKTEM, T., DÜNDAR, M., AYGEN, E. (2015). Ovülasyon İndüksiyonu ve İntrauterin İnseminasyon Sonucu Oluşan Parsiyel Molar ve İkiz Gebelik Kombinasyonu. GORM:Gynecology Obstetrics & Reproductive Medicine, Cilt: 21 - Sayı: 3, 171–173. https://ajindex.com/articles/197456

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References (8)

  1. Marinoff DN, Spitzberg EH, Chueh JT, Goldman JM, Downs T. Delayed-interval delivery in a quadruplet preg- nancy after intrauterine death of a partial molar pregnancy and preterm delivery. A case report. J Reprod Med 1998;43:1051-4.
  2. Kim CH, Kim YH, Kim JW, Kim KM, Cho MK, Kim SM et al. Triplet pregnancy with partial hydatidiform mole co- existing with two fetuses: a case report. J Obstet Gynaecol Res 2008;34:641-4.
  3. Sundari MS, Agarwal P, Mohan J. Triplet pregnancy with partial hydatidiform mole. J Indian Med Assoc 2011;109: 116-7.
  4. Seckl MJ, Sebire NJ, Berkowitz RS. Gestational tro- phoblastic disease. Lancet 2010;376:717-29.
  5. Fowler DJ, Lindsay I, Seckl MJ, Sebire NJ. Routine pre- evacuation ultrasound diagnosis of hydatidiform mole: ex- perience of more than 1000 cases from a regional referral center. Ultrasound Obstet Gynecol 2006;27:56-60.
  6. Massardier J, Golfier F, Journet D, Frappart L, Zalaquett M, Schott AM et al. Twin pregnancy with complete hyda- tidiform mole and coexistent fetus: obstetrical and onco- logical outcomes in a series of 14 cases. Eur J Obstet Gynecol Reprod Biol 2009;143:84-7.
  7. Chew SH, Perlman EJ, Williams R, Kurman RJ, Ronnett BM. Morphology and DNA content analysis in the evalu- ation of first trimester placentas for partial hydatidiform mole (PHM). Hum Pathol 2000;31:914-24. Genest DR. Partial hydatidiform mole: clinicopathologi- cal features, differential diagnosis, ploidy and molecular studies, and gold standards for diagnosis. Int J Gynecol Pathol 2001;20:315-22.
  8. Takagi K, Unno N, Hyodo HE, et al. Complete hydatidi- form mole in a triplet pregnancy coexisting two viable fe- tuses: case report and review of the literature. J Obstet Gynaecol Res 2003; 29:330-8.