Journals / Koç Üniversitesi Hemşirelikte Eğitim ve Araştırma Dergisi / 2020 / Cilt: 17 - Sayı: 1

Evidence Based Complementary Approaches in the Management of Chemotherapy-Induced Peripheral Neuropathy in Cancer Patients

Kanser Hastalarında Kemoterapi Tedavisine Bağlı Gelişen Periferal Nöropatinin Yönetiminde Kanıta Dayalı Tamamlayıcı Yaklaşımlar

Pages
59–65
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

This review is written for the purpose of investigating the research on complementary approaches used in the management of chemotherapyinduced peripheral neuropathy.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Peripheral neuropathy associated with chemotherapy in cancer patients is one of the common symptoms that adversely affects the patients’ daily life activities and life quality.
📊
Key Findings & Data:In studies conducted, peripheral neuropathy was observed in 67–80% of patients in the first year after discontinuation of treatment, and 43% of patients had persistent neuropathy.
💡
Conclusion & Impact:This review is written for the purpose of investigating the research on complementary approaches used in the management of chemotherapyinduced peripheral neuropathy.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Peripheral neuropathy associated with chemotherapy in cancer patients is one of the common symptoms that adversely affects the patients’ daily life activities and life quality. In studies conducted, peripheral neuropathy was observed in 67–80% of patients in the first year after discontinuation of treatment, and 43% of patients had persistent neuropathy. Administration of chemotherapy-induced peripheral neuropathy often leads to a reduction in the dose of medication, intermittent discontinuation or drug termination, which reduces the efficacy of treatment administered to the patient. Although there are many pharmacological and non-pharmacologic approaches to manage peripheral neuropathy, such as acupuncture, reflexology, massage, foot bathing, cryotherapy, scrambler therapy, and other physical activities, this problem remains, and the effectiveness of new methods is being investigated. This review is written for the purpose of investigating the research on complementary approaches used in the management of chemotherapyinduced peripheral neuropathy.

Özet

Kanser hastalarında kemoterapi ile ilişkili periferal nöropati hastanın günlük yaşam aktivitelerini ve yaşam kalitesini olumsuz etkileyen ve yaygın görülen semptomlardan biridir. Yapılan çalışmalarda periferal nöropatinin tedavi kesildikten sonraki ilk 1 yılda %67-80 oranında devam ettiği, bazı hastalarda ise %43 oranında kalıcı nöropati görüldüğü tespit edilmiştir. Kemoterapiye bağlı gelişen periferal nöropatinin yönetiminde sıklıkla ilaç dozunu azaltma, ilaca ara verme veya ilacı sonlandırma yapılmakta olup bu da hastaya uygulanan tedavinin etkinliğinin azalmasına neden olmaktadır. Periferal nöropatinin yönetimine farmakolojik ve akupunktur, refleksoloji, masaj, ayak banyosu, kriyoterapi, scrambler terapi, fiziksel aktivite gibi pek çok non-farmakolojik yaklaşım bulunmasına rağmen bu sorun güncelliğini korumakta ve yeni yöntemlerin etkinliği araştırılmaktadır. Bu derleme kemoterapiye bağlı periferal nöropatinin yönetiminde kullanılan, tamamlayıcı yaklaşımlara ilişkin çalışmaların gözden geçirilmesi amacıyla yazılmıştır

🔖

Cite This Article

KAYIKÇI, E. E., CAN, G. (2020). Evidence Based Complementary Approaches in the Management of Chemotherapy-Induced Peripheral Neuropathy in Cancer Patients. Koç Üniversitesi Hemşirelikte Eğitim ve Araştırma Dergisi, Cilt: 17 - Sayı: 1, 59–65. https://ajindex.com/articles/195790

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (11)

  1. Mols F, Beijers T, Vreugdenhil G, van de Poll-Franse L. Chemotherapyinduced peripheral neuropathy and its association with quality of life: A systematic review. Support Care Cancer. 2014;22(8):2261-9. doi: 10.1007/s00520-014-2255-7
  2. Kerckhove N, Collin A, Conde´ S, Chaleteix C, Pezet D, Balayssac D. Long-term effects, pathophysiological mechanisms, and risk factors of chemotherapy-induced peripheral neuropathies: A comprehensive literature review. Front Pharmacol. 2017;24(8):86. doi: 10.3389/ fphar.2017.00086
  3. Hershman DL, Till C, Wright JD, Awad D, Ramsey SD, Barlow WE, et al. Comorbidities and risk of chemotherapy-induced peripheral neuropathy among participants 65 years or older in Southwest Oncology Group clinical trials. J Clin Oncol. 2016;34(25):3014-22. doi: 10.1200/ JCO.2015.66.2346
  4. Cox-Martin E, Trahan LH, Cox MG, Dougherty PM, Lai EA, Novy DM. Disease burden and pain in obese cancer patients with chemotherapyinduced peripheral neuropathy. Support Care Cancer. 2017;25(6):1873- 9. doi: 10.1007/s00520-017-3571-5
  5. Bao T, Basal C, Seluzicki C, Li SQ, Seidman AD, Mao JJ. Long-term chemotherapy-induced peripheral neuropathy among breast cancer survivors: Prevalence, risk factors, and fall risk. Breast Cancer Res Treat. 2016;159(2):327-33. doi: 10.1007/s10549-016-3939-0
  6. Greenlee H, Hershman DL, Shi Z, Kwan ML, Ergas IJ, Roh JM, et al. BMI, lifestyle factors and taxaneinduced neuropathy in breast cancer patients: The Pathways Study. J Natl Cancer Inst. 2016;109(2):1-8. doi: 10.1093/jnci/djw206
  7. Wang XS, Shi Q, Dougherty PM, Eng C, Mendoza TR, Williams LA, et al. Prechemotherapy touch sensation deficits predict oxaliplatininduced neuropathy in patients with colorectal cancer. Oncology. 2016;90(3):127-35. doi: 10.1159/000443377
  8. Miaskowski C, Mastick J, Paul SM, Topp K, Smoot B, Abrams G, et al. Chemotherapy-Induced Neuropathy in Cancer Survivors. J Pain Symptom Manage. 2017;54(2):204-18.e2. doi: 10.1016/j. jpainsymman.2016.12.342
  9. Boyette-Davis JA, Walters ET, Dougherty PM. Mechanisms involved in the development of chemotherapy-induced neuropathy. Pain Manag. 2015;5(4):285-96. doi: 10.2217/pmt.15.19
  10. Perry MC, Hausheer FH. Chemotherapy induced peripheral neuropathy. In: The Chemotherapy Source Book. 4th ed. Philadelphia: Lippincott Williams & Wilkins; 2008. p. 234-44
  11. Wong R, Major P, Sagar S. Phase 2 study of acupuncture-like transcutaneous nerve stimulation for chemotherapy-induced peripheral neuropathy. Integr Cancer