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Journals / İzmir Tepecik Eğitim Hastanesi Dergisi / 2019 / Cilt: 29 - Sayı: 1

Immune Reconstitution Inflammatory Syndrome During Anti-Tuberculous Therapy: A Case Report

Bir Olguyla Antitüberküloz Tedavi Altında İmmün Rekonstitüsyon İnflamatuvar Sendromu

Aykut TURHAN
Pınar Tosun TAŞAR
Özge TİMUR
Ömer KARAŞAHİN
Alper GÖKGÜL
Doğan Nasır BİNİCİ
Pages
103–106
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Here, we present a case of the rarely reported IRIS in the literature due to central nervous system involvement during recovery in a patient under antituberculous therapy.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Immune reconstitution inflammatory syndrome (IRIS) is defined as the worsening of an existing infection or development of an acute symptomatic infection despite recovery of the immune system.
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Key Findings & Data:It occurs as a result of increased inflammatory response to previously acquired or asymptomatic opportunistic infections or to previously unrecognized antigens.
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Conclusion & Impact:Here, we present a case of the rarely reported IRIS in the literature due to central nervous system involvement during recovery in a patient under antituberculous therapy.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Immune reconstitution inflammatory syndrome (IRIS) is defined as the worsening of an existing infection or development of an acute symptomatic infection despite recovery of the immune system. It occurs as a result of increased inflammatory response to previously acquired or asymptomatic opportunistic infections or to previously unrecognized antigens. Here, we present a case of the rarely reported IRIS in the literature due to central nervous system involvement during recovery in a patient under antituberculous therapy.

Özet

mmün rekonstitüsyon inflamatuvar sendromu (IRIS) immün sistemin düzelmesi ve geri dönüşüne rağmen, mevcut enfeksiyonun kötüleşmesi veya akut semptomatik enfeksiyon ortaya çıkması olarak belirtilmektedir. Bu durum, daha önce teşhis edilmiş veya asemptomatik olan fırsatçı enfeksiyonlara ya da henüz tanınmamış antijenlere karşı artmış inflamatuvar yanıtın sonucu ortaya çıkmaktadır. Olgu sunumundaki amacımız, anti tüberküloz tedavi altında, hastalığın iyileşme evresinde santral sinir sistemi (SSS) tutulumu olması nedeniyle literatürde nadir olarak bildirilen ile immün rekonstitüsyon inflamatuvar sendromunu vurgulamaktır

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Cite This Article

TURHAN, A., TAŞAR, P. T., TİMUR, Ö., KARAŞAHİN, Ö., GÖKGÜL, A., BİNİCİ, D. N. (2019). Immune Reconstitution Inflammatory Syndrome During Anti-Tuberculous Therapy: A Case Report. İzmir Tepecik Eğitim Hastanesi Dergisi, Cilt: 29 - Sayı: 1, 103–106. https://ajindex.com/articles/195541

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References (2)

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