Journals / Çocuk Enfeksiyon Dergisi / 2014 / Cilt: 8 - Sayı: 4

Antibiyotik tedavisine rağmen cerrahi girişim gerektiren bir pseudomonas endokarditi olgusu

A case of pseudomonas endocarditis that required surgical intervention despite antibiotic treatment

Pages
196–199
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Although right-side cardiac valve-based endocarditis caused by P. aeruginosa can be treated with appropriate antibiotic therapy, early surgical treatment is thought to increase treatment success in patients with persistent bacteremia.

📌 3 Key Takeaways

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Objective & Hypothesis:Although infective endocarditis caused by Gramnegative microorganisms is rarely seen, it may lead to morbidity and mortality.
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Key Findings & Data:A 3-year-old female patient with inlet-type ventricular septal defect and pulmonary stenosis was hospitalized upon a provisional diagnosis of infective endocarditis with findings of fever, tachypnea, tachycardia, and hepatomegaly, which developed 2 days after patch closure of the ventricular septal defect.
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Conclusion & Impact:Although right-side cardiac valve-based endocarditis caused by P. aeruginosa can be treated with appropriate antibiotic therapy, early surgical treatment is thought to increase treatment success in patients with persistent bacteremia.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Although infective endocarditis caused by Gramnegative microorganisms is rarely seen, it may lead to morbidity and mortality. Infective endocarditis caused by Pseudomonas strains is very rarely observed. A 3-year-old female patient with inlet-type ventricular septal defect and pulmonary stenosis was hospitalized upon a provisional diagnosis of infective endocarditis with findings of fever, tachypnea, tachycardia, and hepatomegaly, which developed 2 days after patch closure of the ventricular septal defect. A surgical operation was scheduled, because the patient manifested heart failure with growth of Pseudomonas aeruginosa in blood culture, and the infection could not be controlled for more than 3 months despite the appropriate combination of antibiotics. During the operation, the infected ventricular septal defect patch was removed, the tricuspid valve was repaired, and a vegetation was removed from the pulmonary valve. Although right-side cardiac valve-based endocarditis caused by P. aeruginosa can be treated with appropriate antibiotic therapy, early surgical treatment is thought to increase treatment success in patients with persistent bacteremia.

Özet

Gram negatif mikroorganizmaların etken olduğu enfektif endokardit nadir görülmesine rağmen morbidite ve mortaliteye yol açmaktadır. Bu etkenlerden birisi olan Pseudomonas suşlarının neden olduğu enfektif endokarditler oldukça nadir görülmektedir. İnlet tipi geniş ventriküler septal defekt ve pulmoner stenozu olan 3 yaşındaki kız hasta, ventriküler septal defektin yama ile kapatılmasından iki gün sonra gelişen ateş, taşipne ve taşikardi, hepatomegali bulgularıyla enfektif endokardit ön tanısı ile yatırıldı. Kan kültüründe Pseudomonas aeruginosa üreyen hastanın konjestif kalp yetersizliği tablosunda olması, uygun kombine antibiyotik tedavisine karşın üç aydan fazla sürede enfeksiyonun kontrol altına alınamaması nedeniyle operasyon kararı alındı. Operasyon sırasında, enfekte olan ventriküler septal defekt yaması çıkartıldı, triküspit kapak tamiri yapıldı ve pulmoner kapaktan vejetasyon çıkartıldı. P.aeruginosa’nın etken olduğu sağ kalp kaynaklı endokarditte uygun antibiyoterapi ile iyileşme sağlanmasına rağmen bakteriyeminin persiste ettiği hastalarda, geciktirilmeden uygulanan cerrahi tedavinin tedavi başarısını artırabileceği düşünülmüştür.

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Cite This Article

KILIÇ, Ö., ERTUĞRUL, T., OLGAR, Ş., NİŞLİ, K. (2014). Antibiyotik tedavisine rağmen cerrahi girişim gerektiren bir pseudomonas endokarditi olgusu. Çocuk Enfeksiyon Dergisi, Cilt: 8 - Sayı: 4, 196–199. https://ajindex.com/articles/195250

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