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Journals / Çocuk Acil ve Yoğun Bakım Dergisi / 2018 / Cilt: 5 - Sayı: 1

A Case of Fatal Malignant Hyperthermia During Pes Equinovarus Surgery in a Child

Pes Ekinovarus Operasyonu Sırasında Fatal Malign Hipertemi Gelişen Bir Çocuk Olgu

Umut ALTUĞ
Fulya Kamit CAN
AYŞE BERNA ANIL
Fatih DURAK
Meltem ÇAKMAK
Gökçen ÖZÇİFÇİ
Pages
39–42
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

This case is presented to remind the possibility of MH which may be fatal in patients receiving general anesthesia and to emphasize the follow-up and treatment of the patients with MH in pediatric intensive care unit

📌 3 Key Takeaways

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Objective & Hypothesis:Malignant hyperthermia (MH) is a genetic syndrome characterized by hyperthermia, tachycardia, acidosis, and muscle rigidity, often triggered by depolarizing muscle relaxants such as volatile anesthetics and/or succinylcholine.
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Key Findings & Data:A 4.5-year-old boy was admitted to the pediatric intensive care unit considering MH due to persistent fever, tachycardia and end-tidal carbon dioxide elevation which developed during pes equinovarus surgery.
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Conclusion & Impact:This case is presented to remind the possibility of MH which may be fatal in patients receiving general anesthesia and to emphasize the follow-up and treatment of the patients with MH in pediatric intensive care unit
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Malignant hyperthermia (MH) is a genetic syndrome characterized by hyperthermia, tachycardia, acidosis, and muscle rigidity, often triggered by depolarizing muscle relaxants such as volatile anesthetics and/or succinylcholine. MH usually develops following anesthesia induction, but may occur during and after a surgical intervention. A 4.5-year-old boy was admitted to the pediatric intensive care unit considering MH due to persistent fever, tachycardia and end-tidal carbon dioxide elevation which developed during pes equinovarus surgery. In the follow-up, hypercapnia, fever and refractory metabolic acidosis recurred. Despite the administration of dantrolene sodium and supportive treatments, the patient died. This case is presented to remind the possibility of MH which may be fatal in patients receiving general anesthesia and to emphasize the follow-up and treatment of the patients with MH in pediatric intensive care unit

Özet

Malign hipertermi (MH), çoğunlukla volatil anestezikler ve/veya süksinilkolin gibi depolarizan kas gevşeticilerle tetiklenerek oluşan ve hipertermi, taşikardi, asidoz ve kas rijiditesi ile karakterize genetik bir sendromdur. MH genellikle anestezi indüksiyonunu takiben görülür, ancak girişim süresince ve sonrasında da ortaya çıkabilir. Dört buçuk yaşında erkek olgu pes ekinovarus operasyonu sırasında dirençli yüksek ateş, taşikardi ve end-tidal karbondioksitte yükselme olması üzerine MH düşünülerek çocuk yoğun bakıma alındı. Takibinde hiperkarbi, ateş ve dirençli metabolik asidozu tekrar gelişen olgu, dantrolen sodyum ve destek tedavileri verilmesine rağmen kaybedildi. Bu olgu genel anestezi uygulanan hastalarda ölümcül olabilen MH olasılığını hatırlatmak, çocuk yoğun bakımda izlem ve tedavisini vurgulamak için sunulmuştur

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Cite This Article

ALTUĞ, U., CAN, F. K., ANIL, A. B., DURAK, F., ÇAKMAK, M., ÖZÇİFÇİ, G. (2018). A Case of Fatal Malignant Hyperthermia During Pes Equinovarus Surgery in a Child. Çocuk Acil ve Yoğun Bakım Dergisi, Cilt: 5 - Sayı: 1, 39–42. https://ajindex.com/articles/193276

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