Their structures were elucidated by spectral (UV, IR, 1D-, and 2D-NMR, and HRMS) methods.
📌 3 Key Takeaways
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Objective & Hypothesis:Three new diterpenoids, piliferol (2a, 20-dihydroxy-12-oxo- abieta-9(11),13-dien-8,20-ether) (1), salvipiliferol (2a, 10b -dihydroxy-12-oxo-norabieta-9(11),13-dien) (2), and piliferalactone (2a ,8-dihydroxy-12-oxo-abieta-9(11),13-dien-20-oic acid-8,20-lactone) (3), together with 7 known compounds, ursolic acid, oleanolic acid, betulinic acid, a -amyrin, lupeol, b -sitosterol, and pectolinarigenin, have been isolated from the aerial parts of an endemic Salvia species, S. pilifera.
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Key Findings & Data:Three new diterpenoids, piliferol (2a, 20-dihydroxy-12-oxo- abieta-9(11),13-dien-8,20-ether) (1), salvipiliferol (2a, 10b -dihydroxy-12-oxo-norabieta-9(11),13-dien) (2), and piliferalactone (2a ,8-dihydroxy-12-oxo-abieta-9(11),13-dien-20-oic acid-8,20-lactone) (3), together with 7 known compounds, ursolic acid, oleanolic acid, betulinic acid, a -amyrin, lupeol, b -sitosterol, and pectolinarigenin, have been isolated from the aerial parts of an endemic Salvia species, S. pilifera.
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Conclusion & Impact:Their structures were elucidated by spectral (UV, IR, 1D-, and 2D-NMR, and HRMS) methods.
Three new diterpenoids, piliferol (2a, 20-dihydroxy-12-oxo- abieta-9(11),13-dien-8,20-ether) (1), salvipiliferol (2a, 10b -dihydroxy-12-oxo-norabieta-9(11),13-dien) (2), and piliferalactone (2a ,8-dihydroxy-12-oxo-abieta-9(11),13-dien-20-oic acid-8,20-lactone) (3), together with 7 known compounds, ursolic acid, oleanolic acid, betulinic acid, a -amyrin, lupeol, b -sitosterol, and pectolinarigenin, have been isolated from the aerial parts of an endemic Salvia species, S. pilifera. Their structures were elucidated by spectral (UV, IR, 1D-, and 2D-NMR, and HRMS) methods.
Özet
Three new diterpenoids, piliferol (2a, 20-dihydroxy-12-oxo- abieta-9(11),13-dien-8,20-ether) (1), salvipiliferol (2a, 10b -dihydroxy-12-oxo-norabieta-9(11),13-dien) (2), and piliferalactone (2a ,8-dihydroxy-12-oxo-abieta-9(11),13-dien-20-oic acid-8,20-lactone) (3), together with 7 known compounds, ursolic acid, oleanolic acid, betulinic acid, a -amyrin, lupeol, b -sitosterol, and pectolinarigenin, have been isolated from the aerial parts of an endemic Salvia species, S. pilifera. Their structures were elucidated by spectral (UV, IR, 1D-, and 2D-NMR, and HRMS) methods.
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