Journals / Turkish Journal of Chemistry / 2013 / Cilt: 37 - Sayı: 4

Terpenoids, essential oil composition, fatty acid pro le, and biological activities of Anatolian Salvia fruticosa Mill.

Pages
619–632
Publication Date
2022-11-05
DOI
—
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⚡ TL;DR(Too Long; Didn't Read)

The antioxidant activity according to 6 complementary tests and anticholinesterase potential of the methanol extracts and triterpenoids $alpha$-amyryltetracosanoate, oleanolic acid, ursolic acid, and sitosterol acetate were also investigated, and methanol extract exhibited the highest antioxidant and anticholinesterase activity, surpassing the other tested extracts and pure compounds.

📌 3 Key Takeaways

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Objective & Hypothesis:The hexane and dichloromethane extracts, obtained by re-extraction of the methanol extract of Salvia fruticosa Mill., a orded 7 diterpenoids (carnosol, carnosic acid, carnosic acid 12-methyl ether, rosmadial, isorosmanol, ferruginol, and manool), 4 triterpenoids ( -amyryltetracosanoate, oleanolic acid, ursolic acid, and erythrodiol), a steroid (3-acetylsitosterol), and aavone (salvigenin).
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Key Findings & Data:The galls (apples) of the collected plant were separately extracted with hexane to a ord fatty acids composed mainly of oleic acid (29%), palmitoleic acid (29%), and stearic acid (23.20%), which exhibited high anticholinesterase activity, particularly against BChE.
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Conclusion & Impact:The antioxidant activity according to 6 complementary tests and anticholinesterase potential of the methanol extracts and triterpenoids $alpha$-amyryltetracosanoate, oleanolic acid, ursolic acid, and sitosterol acetate were also investigated, and methanol extract exhibited the highest antioxidant and anticholinesterase activity, surpassing the other tested extracts and pure compounds.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

The hexane and dichloromethane extracts, obtained by re-extraction of the methanol extract of Salvia fruticosa Mill., a orded 7 diterpenoids (carnosol, carnosic acid, carnosic acid 12-methyl ether, rosmadial, isorosmanol, ferruginol, and manool), 4 triterpenoids ( -amyryltetracosanoate, oleanolic acid, ursolic acid, and erythrodiol), a steroid (3-acetylsitosterol), and aavone (salvigenin). The galls (apples) of the collected plant were separately extracted with hexane to a ord fatty acids composed mainly of oleic acid (29%), palmitoleic acid (29%), and stearic acid (23.20%), which exhibited high anticholinesterase activity, particularly against BChE. The essential oil, obtained from the aerial parts of the plant, exhibited high AChE inhibitory activity, consisting of mainly 1,8-cineol (58.89%). The antioxidant activity according to 6 complementary tests and anticholinesterase potential of the methanol extracts and triterpenoids $alpha$-amyryltetracosanoate, oleanolic acid, ursolic acid, and sitosterol acetate were also investigated, and methanol extract exhibited the highest antioxidant and anticholinesterase activity, surpassing the other tested extracts and pure compounds.

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Cite This Article

ÖZTÜRK, M., KOLAK, U., TOPÇU, G., KUŞMAN, T., DEMİRKOZ, A. A. B., ULUBELEN, A. (2022). Terpenoids, essential oil composition, fatty acid pro le, and biological activities of Anatolian Salvia fruticosa Mill.. Turkish Journal of Chemistry, Cilt: 37 - Sayı: 4, 619–632. https://ajindex.com/articles/601658

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