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Journals / Turkish Journal of Chemistry / 2013 / Cilt: 37 - Sayı: 6

N -functionalized benzimidazol-2-ylidene silver complexes: synthesis, characterization, and antimicrobial studies

N-functionalized benzimidazol-2-ylidene silver complexes: synthesis, characterization, and antimicrobial studies

Yetkin GÖK
Senem AKKOÇ
Özlem Özeroğlu ÇELİKAL
İlknur ÖZDEMİR
Selami GÜNAL
Elif SAYIN
Pages
1007–1013
Publication Date
2013-06-01
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Using the agar dilution procedure recommended by the Laboratory and Clinical Standards Institute, the antimicrobial activities of all the silver-NHC complexes were studied against 2 gram-negative bacterial strains (Pseudomonas aeruginosa and Escherichia coli), 2 gram-positive bacterial strains (Enterococcus faecalis and Staphylococcus aureus), and 2 fungi (Candida tropicalis and Candida albicans).

📌 3 Key Takeaways

🎯
Objective & Hypothesis:2-Methoxyethyl, 2-diethylaminoethyl, and 2-phenylethyl-substituted N-heterocyclic carbene (NHC) precursors were treated with Ag2CO3 to yield silver(I)-NHC complexes (1a--g) in dichloromethane as a solvent at room temperature.
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Key Findings & Data:The 7 new silver-NHC complexes were fully characterized by means of 1H NMR, 13C NMR, and elemental analysis techniques.
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Conclusion & Impact:Using the agar dilution procedure recommended by the Laboratory and Clinical Standards Institute, the antimicrobial activities of all the silver-NHC complexes were studied against 2 gram-negative bacterial strains (Pseudomonas aeruginosa and Escherichia coli), 2 gram-positive bacterial strains (Enterococcus faecalis and Staphylococcus aureus), and 2 fungi (Candida tropicalis and Candida albicans).
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:N-Heterocyclic carbene · benzimidazol-2-ylidene · silver complex

Abstract

2-Methoxyethyl, 2-diethylaminoethyl, and 2-phenylethyl-substituted N-heterocyclic carbene (NHC) precursors were treated with Ag2CO3 to yield silver(I)-NHC complexes (1a--g) in dichloromethane as a solvent at room temperature. The 7 new silver-NHC complexes were fully characterized by means of 1H NMR, 13C NMR, and elemental analysis techniques. Using the agar dilution procedure recommended by the Laboratory and Clinical Standards Institute, the antimicrobial activities of all the silver-NHC complexes were studied against 2 gram-negative bacterial strains (Pseudomonas aeruginosa and Escherichia coli), 2 gram-positive bacterial strains (Enterococcus faecalis and Staphylococcus aureus), and 2 fungi (Candida tropicalis and Candida albicans).

Özet

2-Methoxyethyl, 2-diethylaminoethyl, and 2-phenylethyl-substituted N-heterocyclic carbene (NHC) precursors were treated with Ag2CO3 to yield silver(I)-NHC complexes (1a--g) in dichloromethane as a solvent at room temperature. The 7 new silver-NHC complexes were fully characterized by means of 1H NMR, 13C NMR, and elemental analysis techniques. Using the agar dilution procedure recommended by the Laboratory and Clinical Standards Institute, the antimicrobial activities of all the silver-NHC complexes were studied against 2 gram-negative bacterial strains (Pseudomonas aeruginosa and Escherichia coli), 2 gram-positive bacterial strains (Enterococcus faecalis and Staphylococcus aureus), and 2 fungi (Candida tropicalis and Candida albicans).

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Cite This Article

GÖK, Y., AKKOÇ, S., ÇELİKAL, Ö. Ö., ÖZDEMİR, İ., GÜNAL, S., SAYIN, E. (2013). N -functionalized benzimidazol-2-ylidene silver complexes: synthesis, characterization, and antimicrobial studies. Turkish Journal of Chemistry, Cilt: 37 - Sayı: 6, 1007–1013. https://ajindex.com/articles/184624

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