Journals / JAREM / 2019 / Cilt: 9 - Sayı: 2

Possible Risk Factors Associated with Allergic Diseases Among Perinatal and Infancy Period

Perinatal ve Süt Çocukluğu Döneminde Alerjik Hastalıklara Eğilim Yarattığı Düşünülen Olası Risk Faktörleri

Journal
JAREM
Pages
91–96
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: Maternal allergy history and tobacco smoking, prenatal and postnatal tobacco exposure, breastfeeding less than 4 months and feeding with formula before 4th month of life were associated risk factors for developing allergic diseases.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: The aim of the study was to investigate perinatal and early-chihdood risk factors which facilitate development of allergic diseases.
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Key Findings & Data:Methods: This study was held between the years 2009-2010 among allergic children (n=188) aged 1-16 years, followed in the Allergy Immunology outpatient clinic.
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Conclusion & Impact:Conclusion: Maternal allergy history and tobacco smoking, prenatal and postnatal tobacco exposure, breastfeeding less than 4 months and feeding with formula before 4th month of life were associated risk factors for developing allergic diseases.
🔬Design:Survey & Empirical Study
📍Scope:2009-2010 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: The aim of the study was to investigate perinatal and early-chihdood risk factors which facilitate development of allergic diseases. Methods: This study was held between the years 2009-2010 among allergic children (n=188) aged 1-16 years, followed in the Allergy Immunology outpatient clinic. The control group was composed of healthy chidren of healthcare personnel and healthy children followed in the outpatient clinic (n=72). A survey which examined the risk factors associated with asthma, allergic rhinitis, atopic dermatitis and urticaria-angioedema was used. Results:The number of male children in the case and control group was 106 (56.4%) and 37 (48.6%), respectively. The mean age of case and control group was 7.73±3.31 and 7.06±2.86 years, respectively. The mean age of patients diagnosed atopic dermatitis, asthma and allergic rhinitis was 1.77±1.30; 3.62±2.80 and 4.51±2.63 years, respectively. When comparing the case and control group according to risk factors; maternal allergy history (p<0.01), maternal tobacco smoking (p=0.002), prenatal and postnatal tobacco exposure (p=0.000), breastfeeding less than 4 months (p=0.01) and feeding with formula before 4th month of life (p=0.038) was significantly higher among allerigic group. Conclusion: Maternal allergy history and tobacco smoking, prenatal and postnatal tobacco exposure, breastfeeding less than 4 months and feeding with formula before 4th month of life were associated risk factors for developing allergic diseases.

Özet

Amaç: Perinatal ve erken çocukluk döneminde alerjik hastalık gelişimine zemin hazırladığı düşünülen risk faktörlerinin araştırılması amaçlanmıştır. Yöntemler: Bu çalışma 2009-2010 tarihleri arasında Alerji ve İmmünoloji Polikliniği'ne gelen 1-16 yaş arası alerjik hastalık tanısı alan çocuklarda (n=188) yapıldı. Kontrol grubu çalışan sağlık personelinin sağlıklı çocuklarından ve polikliniğe gelen 1-16 yaş arasındaki sağlıklı çocuklardan (n=72) oluşturuldu. Çalışmada astım, alerjik rinit, atopik dermatit/ekzema ve ürtiker-anjioödemle ile ilişkili olduğu düşünülen risk faktörlerinin sorgulandığı bir anket formu kullanıldı. Bulgular: Vaka ve kontrol grubunda erkek çocukların sayısı sırasıyla 106 (%56,4) ve 37 (%48,6) idi. Vaka ve kontrol grubunun yaş ortalaması sırasıyla 7,73 ± 3,31 ve 7,06±2,86 yıl idi. Atopik dermatit, astım/reaktif hava yolu hastalığı ve alerjik rinit hastalarında ortalama semptom yaşı sırasıyla 1,77±1,30 yıl, 3,62±2,80 yıl ve 4,51±2,63 yıl idi. Vaka ve kontrol grubu ankette sorgulanan risk faktörleri açısından karşılaştırıldığında annede alerji öyküsü (doktor tanılı astım/alerjik rinit/ekzema varlığı) (p˂0,01), annede sigara kullanımı (p=0,002), prenatal (p=0,000) ve postnatal (p=0,000) sigara maruziyeti, anne sütü ile 4 aydan daha kısa süreli beslenme (p=0,01) ve 4. aydan önce formül süt başlama (p=0,038) vaka grubunda anlamlı olarak daha yüksekti. Sonuç: Çalışmamızda maternal alerji öyküsü ve sigara kullanımının, prenatal ve postnatal sigara maruziyetinin, 4 aydan daha kısa süre anne sütü ile beslenmenin ve hayatın 4. ayından önce formül süt başlanmasının alerjik hastalık riskini arttırdığını düşünmekteyiz.

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Cite This Article

AKTAŞ, S., SAY, A. (2019). Possible Risk Factors Associated with Allergic Diseases Among Perinatal and Infancy Period. JAREM, Cilt: 9 - Sayı: 2, 91–96. https://ajindex.com/articles/178284

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