Journals / Flora İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi / 2019 / Cilt: 24 - Sayı: 4

Generalized Tetanus in a Geriatric Age Group Patient

Geriatrik Yaş Grubundaki Bir Hastada Jeneralize Tetanoz

Pages
387–390
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The patient died on the 35th day of follow-up due to ventilator associated Acinetobacter baumannii complex pneumonia and nephrotoxicity related to colistin therapy.

📌 3 Key Takeaways

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Objective & Hypothesis:Tetanus is a vaccine preventable infectious disease which presents itself in four clinical types as generalized, localized, cephalic and neonatal tetanus.
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Key Findings & Data:Generalized tetanus generally occurs in elderly patients, in whom the level of serum antitoxin is inadequate, with high mortality rates.
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Conclusion & Impact:The patient died on the 35th day of follow-up due to ventilator associated Acinetobacter baumannii complex pneumonia and nephrotoxicity related to colistin therapy.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Tetanus is a vaccine preventable infectious disease which presents itself in four clinical types as generalized, localized, cephalic and neonatal tetanus. Generalized tetanus generally occurs in elderly patients, in whom the level of serum antitoxin is inadequate, with high mortality rates. As muscle spasms and autonomic dysfunction are the major findings, patients should be followed in intensive care units. This necessity may cause healthcare associated infections and complications. In this case presentation, a 68-year-old male patient who had developed generalized tetanus was reported. The patient admitted to the emergency service two days after a nail wound on his left foot sole and received only tetanus vaccine for prophylaxis. Symptoms started six days after injury. The patient could only be diagnosed with tetanus five days after the first clinical findings. The patient was intubated and followed in the intensive care unit. 3000 IU human tetanus immunoglobulin and 14-day course of metronidazole therapy was administered. Muscle spasms were managed via rocuronium and midasolame. The patient died on the 35th day of follow-up due to ventilator associated Acinetobacter baumannii complex pneumonia and nephrotoxicity related to colistin therapy.

Özet

Tetanoz jeneralize, lokalize, sefalik ve neonatal tetanoz şeklinde dört klinik formda kendini gösteren, aşı ile önlenebilir bir infeksiyon hastalığıdır. Jeneralize tetanoz genellikle serum antitoksin düzeylerinin yetersiz olduğu ileri yaştaki hastalarda ve yüksek mortalite hızıyla görülmektedir. Kas spazmları ve otonomik disfonksiyon majör klinik bulgular olduğundan, hastalar yoğun bakım ünitelerinde takip edilmelidir. Bu gereklilik sağlık bakımı ilişkili infeksiyonlar ve komplikasyonlara neden olabilmektedir. Bu olgu sunumunda, jeneralize tetanoz gelişen 68 yaşında erkek bir hasta bildirilmiştir. Hasta sol ayak tabanından çivi ile yaralandıktan iki gün sonra acil servise başvurmuş ve tetanoz profilaksisi için yalnız tetanoz aşısı yapılmıştır. Semptomlar yaralanmadan altı gün sonra başlamıştır. Hastaya tetanoz tanısı klinik bulguların ortaya çıkmasından beş gün sonra konulabilmiştir. Hasta entübe edilmiş ve yoğun bakım ünitesinde takibe alınmıştır. 3000 IU insan tetanoz immünglobulini ve 14 gün süreyle metronidazol tedavisi uygulanmıştır. Kas spazmları rokuronyum ve midazolamla kontrol altına alınmıştır. Hasta takibinin 35. gününde ventilatör ilişkili Acinetobacter baumannii complex pnömonisi ve kolistin tedavisi ilişkili nefrotoksisite nedeniyle kaybedilmiştir.

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Cite This Article

GÜLTEN, E., ÖZGÜVEN, E., TÜRK, D. Ö., ATSAL, A. Ö. (2019). Generalized Tetanus in a Geriatric Age Group Patient. Flora İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi, Cilt: 24 - Sayı: 4, 387–390. https://ajindex.com/articles/176339

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