Journals / Glokom Katarakt / 2017 / Cilt: 12 - Sayı: 1

Comparison of the Results of Spectral Domain- Optical Coherence Tomograp- hy and Computerized Automated Perimetry in Primary Open Angle Glaucoma

Primer Açık Açılı Glokomda Spektral Domain-Optik Koherens Tomografi Sonuçlarının Bilgisayarlı Görme Alanı ile Karşılaştırılması

Pages
26–31
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: If structural and functional tests are considered together, new generation OCT devices contribute more to the diagnosis and monitoring of glaucoma patients.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Purpose: We aimed to compare the results of the computerized automated perimetry (CAP) and new generation, high definition Spectral Domain Optical Coherence Tomography (SD- OCT) tests in eyes with primary open-angle glaucoma (POAG).
📊
Key Findings & Data:Material and Methods: 35 patients with POAG and 29 healty volunteers were enrolled in this study.
💡
Conclusion & Impact:Conclusion: If structural and functional tests are considered together, new generation OCT devices contribute more to the diagnosis and monitoring of glaucoma patients.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Purpose: We aimed to compare the results of the computerized automated perimetry (CAP) and new generation, high definition Spectral Domain Optical Coherence Tomography (SD- OCT) tests in eyes with primary open-angle glaucoma (POAG). Material and Methods: 35 patients with POAG and 29 healty volunteers were enrolled in this study. Peripapillary retinal nevre fiber layer (RNFL) thickness and perifoveal macular thickness (the distance between internal limiting membrane and ganglion cell complex) was analyzed by SD-OCT (Nidek RS-3000 LITE, Japan). Mean deviation (MD) and patern standard deviation (PSD) values were obtained by using static automatic perimetry (Haag-Streit Diagnosrics Octopus 900, SN 206, V 2.2.0/ 3.2.1 EyeSuiteTM Static perimetry). T-test and Pearson correlation test was used between the dependent and independent variables. Results: The average age in cases of POAG was 56.82 , female/ male ratio was 15/20. The average age in control group was 60,86 , female/ male ratio was 17/12. The mean peripapillary RNFL thickness was measured 106.31±18.05 ?m in POAG group and 110.72±14,23 ?m in control group. Although mean RNFL thickness in eyes with glaucoma is low, it was not statistically significant (p=0.069). Central macular thickness was found 217,99±21,64 ?m and 257,83±22,17 ?m in eyes with glaucoma and control group respectively. Central macular thickness was thin statistically significant in POAG (p<0.001). It was revealed correlation between SD-OCT and CAP in all groups. Conclusion: If structural and functional tests are considered together, new generation OCT devices contribute more to the diagnosis and monitoring of glaucoma patients.

Özet

Amaç: Primer açık açılı glokomlu (PAAG) gözlerde bilgisayarlı görme alanı (BGA) ve yeni nesil, yüksek çözünürlüklü Spektal Domain Optik Koherens Tomografi (SD- OKT) sonuçlarını karşılaştırmayı amaçladık. Gereç ve Yöntem: 35 PAAG hastası ve 29 sağlıklı gönüllü çalışmaya dahil edildi. Tüm olguların peripapiller retina sinir lifi tabakası (RSLT) kalınlığı ve perifoveal maküla kalınlığı (iç limitan membran- gangliyon hücre kompleksi mesafesi) SD-OKT (Nidek RS-3000 LITE, Japan) ile analiz edildi. Statik otomatik perimetri (Haag-Streit Diagnosrics Octopus 900, SN 206, V 2.2.0/ 3.2.1 EyeSuiteTM Static perimetry) ile ortalama sapma (OS) ve patern standart sapma (PSS) değerleri kaydedildi. Bağımlı ve bağımsız değişkenler arasında T-test ve Pearson korelasyonu kullanıldı. Bulgular: PAAG olgularında ortalama yaş 56.82±7,60 , kadın/erkek oranı 15/20 idi. Kontrol grubunda ortalama yaş 60,86±7,51 (4570), kadın/erkek oranı 17/12 idi. Ortalama peripapiller RSLT kalınlığı glokom grubunda 106.31±18.05 ?m ve kontrol grubunda 110.72±14,23 ?m ölçüldü. Glokomlu gözlerde ortalama RSLT kalınlığı düşük olmasına rağmen istatistiksel olarak anlamlı değildi. (p=0.069). Santral maküla kalınlığı ise glokomlu gözlerde ve kontrol grubunda sırasıyla 217,99±21,64 ?m ve 257,83±22,17 ?m bulundu. Santral maküla kalınlığı PAAG'ta istatistiksel olarak anlamlı derecede inceydi (p<0.001). Tüm gruplarda SD-OKT ve BGA parametreleri arasında uyumlu bir ilişki vardı. Sonuç: Yapısal ve fonksiyonel testlerin bir bütün olarak değerlendirildiğinde yeni nesil OKT cihazlarının glokom olgularının tanı ve takibine daha fazla katkı sağlayacağını düşünmekteyiz.

🔖

Cite This Article

TOYRAN, S., BİLGİN, S., KARAHAN, E., UYAR, M., AKAY, F. (2017). Comparison of the Results of Spectral Domain- Optical Coherence Tomograp- hy and Computerized Automated Perimetry in Primary Open Angle Glaucoma. Glokom Katarakt, Cilt: 12 - Sayı: 1, 26–31. https://ajindex.com/articles/173408

References (7)

  1. Quıgley HA, Katz J, Derick RJ, et al.: An evaluation of optic disc and nerve fiber layer examinations in monitoring progression of early glaucoma damage. Ophthalmology. 1992; 99: 19-28. Quıgley HA,Miller NR, George T.: Clinical Evaluation of nerve fiber layer assesment, Arch Ophthalmology. 1980; 98: 1564 Polo V, Larrosa JM, Ferreras A, et al. Retinal nerve fiber layer evaluation in open angle glaucoma. Optimum criteria for optical coherence tomography. Ophthalmologica 2009; 223: 2-6.
  2. Williams ZY, Schuman JS, Gamell L, et al. Optical coherence tomography measurement of nerve fiber layer thickness and the likelihood of a visual field defect. Am J Ophthalmol. 2002; 134: 546. Wollstein G, Schuman JS, Price LL, et al. Optical coherence tomography longitudinal evaluation of retinal nerve fiber layer thickness in glaucoma. Arch Ophthalmol 2005; 123: 464-70. Üstündağ C. Primer Açık Açılı Glokomda Görüntüleme Yöntem- leri. T Klin Oftalmolji. 2004; 13: 38-45. Greenfield DS. Ophthal- mic Imaging. Atlas of Ophthalmology. Parrish II RK, ed. Current Medicine. Philadelphia. 1999; (6): 38-44.
  3. Sull AC, Vuong LN, Price LL, et al. Comparison of spectral/ fou- rier domain optical coherence tomography instruments for asses- ment of normal maculer thickness. Retina 2010; 30: 235-45.
  4. Heijl A, Lindgren G, Olsson J, et al. Visual field interpretation with empiric probability maps. Arch Ophthalmol 1989; 107: 204 Cohen, J. (1988). Statistical power analysis for the behavioral sciences (2nd ed.) Hillsdale, NJ: Lawrence Erlbaum Associates. Schuman JS. Spectral domain optical coherence tomography for glaucoma. Trans Am Ophthalmol Soc 2008; 106: 426-458.
  5. Zangwil LM, Bowd C, Charles C, et al. Discriminating between normal and glaucomatous eyes using the Heidelberg retina to- mography,gdx nevre fiber analyzer, and OCT, Arch.Ophtalmolo- gy. 2001; 119: 985-993.
  6. Baumann M, Gentile RC, Liebmann JM, et al.: Reproducibility of retinal thickness measurements in normal eyes using optical coherence tomography. Ophthalmic Surg Lasers. 1998; 29: 280 Furuichi M, Kashiwagi K, Furuichi Y.: Comparison of the ef- fectiveness of scanning laser polarimetry and optical coherence tomography for estimating optic nevre fiber layer thickness in patients with glaucoma- Ophthalmologica. 2002; 216: 168-174
  7. Schuman JS, Hee MR, Puliafito CA, et al.: Quantificationbof nerve fiber layer thickness in normal and glaucomatous eyes us- ing optical coherence tomography. Arch Ophthalmol. 1995; 113: 596 Wojtkowski M, Sriniv