Journals / GORM:Gynecology Obstetrics & Reproductive Medicine / 2017 / Cilt: 23 - Sayı: 3

The Relationship of Myometrial Invasion Between Other Prognostic Parameters in Endometrial Cancer

Pages
158–162
DOI
—
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⚡ TL;DR(Too Long; Didn't Read)

Recurrence rates, disease free survival and overallsurvival rates were evaluated in endometrial cancer patients with MI>50%.

📌 3 Key Takeaways

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Objective & Hypothesis:OBJECTIVE: The aim of this study is to investigate the relationship between deep myometrial invasionand other prognostic factors in endometrial cancer.
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Key Findings & Data:Recurrence rates, disease free survival and overallsurvival rates were evaluated in endometrial cancer patients with MI>50%.
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Conclusion & Impact:Other prognostic factors especially lympho-vascular space invasion and pelvic/para-aortic lymph node metastasis were significantly higherwhen myometrial invasion is above 50% and also there was significant difference in recurrence rates,overall survival and disease free survival rates between patients with superficial and deep myometrialinvasion (p<0.05).CONCLUSION: Myometrial invasion is an important prognostic parameter and can be determined intraoperatively to decide whether to perform pelvic and para-aortic lymph node dissection.
🔬Design:Research Article
📍Scope:2001 Verileri
⚙️Variables:Domain Parameters

Abstract

OBJECTIVE: The aim of this study is to investigate the relationship between deep myometrial invasionand other prognostic factors in endometrial cancer. Recurrence rates, disease free survival and overallsurvival rates were evaluated in endometrial cancer patients with MI>50%. STUDY DESIGN: A total of 132 patients with endometrial cancer who underwent surgical treatment between 2001 and 2011 were identified. Demographic, clinicopathological, surgical/adjuvant treatment andfollow-up data were extracted.RESULTS: Pelvic lymph node invasion ratio was 28,9% and para-aortic lymph node invasion ratio was15,5% in patients with myometrial invasion is greater than 50%. Other prognostic factors especially lympho-vascular space invasion and pelvic/para-aortic lymph node metastasis were significantly higherwhen myometrial invasion is above 50% and also there was significant difference in recurrence rates,overall survival and disease free survival rates between patients with superficial and deep myometrialinvasion (p<0.05).CONCLUSION: Myometrial invasion is an important prognostic parameter and can be determined intraoperatively to decide whether to perform pelvic and para-aortic lymph node dissection.

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Cite This Article

BAKIR, M. S., TAHAOĞLU, A. E., ERDOĞDU, E., Dane, C. (2017). The Relationship of Myometrial Invasion Between Other Prognostic Parameters in Endometrial Cancer. GORM:Gynecology Obstetrics & Reproductive Medicine, Cilt: 23 - Sayı: 3, 158–162. https://ajindex.com/articles/167563

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