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Journals / Psikiyatride Güncel Yaklaşımlar / 2026 / Cilt: 18 Sayı: Supplement 1 Özel Sayı

Relationship Between Visual Field, Intraocular Pressure, and Retinal Nerve Fiber Layer in Patients with Open-Angle Glaucoma and Depression Level

Açık Açılı Glokom Hastalarında Görme Alanı, Göz İçi Basıncı ve Retina Sinir Lifi Tabakası ile Depresyon Düzeyi Arasındaki İlişki

Jülide Keleş(fethi sekin şehir hastanesi)0009-0001-6389-0763
Sevler Yıldız(Fethi Sekin Şehir Hastanesi)0000-0002-9951-9093
Sinem Keser(Fethİ Sekin Şehir Hastanesi)0000-0002-9181-6691
Ayşe Rümeysa Yaman Baran(Fethi Sekin Şehir Hastanesi)0000-0003-3141-2078
Pages
109–118
Publication Date
2026-10-18
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

This finding suggests that the development of depression in glaucoma may be associated not only with objective parameters of the disease but also with age and other personal factors.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: The aim of this study was to investigate the relationship between depression levels and parameters such as intraocular pressure variability, visual field scores, and retinal nerve fiber layer (RNFL) thickness in patients with primary open-angle glaucoma (POAG).
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Key Findings & Data:Method: A total of 50 patients diagnosed with POAG were included in this study.
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Conclusion & Impact:This finding suggests that the development of depression in glaucoma may be associated not only with objective parameters of the disease but also with age and other personal factors.
🔬Design:Modeling & Simulation
📍Scope:Comprehensive Sample
⚙️Variables:Primer açık açılı glokom · görme alanı · retina sinir lifi analizi

Abstract

Objective: The aim of this study was to investigate the relationship between depression levels and parameters such as intraocular pressure variability, visual field scores, and retinal nerve fiber layer (RNFL) thickness in patients with primary open-angle glaucoma (POAG). Method: A total of 50 patients diagnosed with POAG were included in this study. All participants underwent a comprehensive ophthalmological evaluation including intraocular pressure measurements and retinal nerve fiber layer (RNFL) thickness measurements using standard automated perimetry for visual field analysis and optical coherence tomography to assess the functional and structural damage caused by glaucoma. The Beck Depression Inventory (BDI) was administered to all participants to assess their depression levels. Results: There were no significant relationship between BDI scores and intraocular pressure, visual field, retinal nerve fiber analysis, or number of medications used in glaucoma patients. In the multiple linear regression analysis, the model was found to be statistically significant (F=3.805) and explained 25.3% of the variance in BDI scores. Conclusion: Patients with primary open-angle glaucoma exhibit mild depressive symptoms regardless of the severity of the disease’s impact on the eye, and that the level of depressive symptoms increases with age. This finding suggests that the development of depression in glaucoma may be associated not only with objective parameters of the disease but also with age and other personal factors.

Özet

Amaç: Bu çalışmanın amacı, primer açık açılı glokom (PAAG) hastalarında göz içi basıncı düzensizliği, görme alanı skorları ve retina sinir lifi (RNFL) kalınlığı gibi parametrelerle depresyon düzeyi arasındaki ilişkinin incelenmesidir. Yöntem: Bu çalışmaya PAAG tanısı almış toplam 50 hasta dahil edildi. Tüm katılımcılara kapsamlı oftalmolojik değerlendirme yapıldı. Bu kapsamda göz içi basıncı ölçümleri, glokomun fonksiyonel ve yapısal hasarını değerlendirmek amacıyla standart otomatik perimetri ve görme alanı analizi ile optik koherens tomografi kullanılarak RNFL kalınlık ölçümleri yapıldı. Depresyon düzeyleri Beck Depresyon Ölçeği (BDÖ) ile değerlendirildi. Bulgular: Glokom hastalarında göz içi basıncı, görme alanı, retina sinir lifi analizi ve kullanılan ilaç sayısı ile BDÖ puanları arasında anlamlı ilişki saptanmamıştır. Çoklu doğrusal regresyon analizi model istatistiksel olarak anlamlı bulundu (F=3,805) ve BDÖ puanlarındaki varyansın %25,3'ünü açıklamıdı. Sonuç: Primer açık açılı glokom hastalarının glokomun gözü etkileme şiddetinden bağımsız olarak hafif düzeyde depresif belirti gösterdiklerini, yaş arttıkça depresif belirti düzeylerinin arttığı saptanmıştır. Bu bulgu, glokomda depresyon gelişiminin yalnızca glokom hastalığının objektif parametreleriyle değil, yaş ve diğer kişisel faktörlerle de ilişkili olabileceğini göstermektedir.

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Cite This Article

Keleş, J., Yıldız, S., Keser, S., Baran, A. R. Y. (2026). Relationship Between Visual Field, Intraocular Pressure, and Retinal Nerve Fiber Layer in Patients with Open-Angle Glaucoma and Depression Level. Psikiyatride Güncel Yaklaşımlar, Cilt: 18 Sayı: Supplement 1 Özel Sayı, 109–118. https://doi.org/10.18863/pgy.1896367

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