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Journals / Akdeniz Diş Hekimliği Dergisi / 2026 / Cilt: 4 Sayı: 1

Post-COVID-19 Extensive Maxillary Actinomycotic Osteonecrosis: A Rare Case Report

Mehmet Ali Altay(AKDENIZ UNIVERSITY, FACULTY OF DENTISTRY)0000-0001-8886-4783
Cennet Neslihan Eroğlu(AKDENIZ UNIVERSITY, FACULTY OF DENTISTRY)0000-0002-0856-7998
Büşra Karaca(BURDUR MEHMET AKİF ERSOY UNIVERSITY, FACULTY OF DENTISTRY)0000-0002-1262-7404
Saffet Uğur Doğan(AKDENIZ UNIVERSITY, FACULTY OF DENTISTRY)0009-0000-4539-5577
Pages
63–69
Publication Date
2025-04-30
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

This case may shed light on clinicians to give importance to the follow-up of patients with Covid-19 and its variants, especially if they have a history of hospitalization, to provide a differential diagnosis for PC-RONJ even if the interval is long, and not to skip the microbiological evaluation stage.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Osteonecrosis can be seen in post-Covid-19 patients due to the damage to their immune systems and the medications they take.
📊
Key Findings & Data:The medical history of the 48-year-old patient, who had received treatment for Covid-19 in the intensive care unit about 1 year ago and had no systemic disease, revealed left palatinal and buccal bone exposure, suppuration and oroantral relationship.
💡
Conclusion & Impact:This case may shed light on clinicians to give importance to the follow-up of patients with Covid-19 and its variants, especially if they have a history of hospitalization, to provide a differential diagnosis for PC-RONJ even if the interval is long, and not to skip the microbiological evaluation stage.
🔬Design:Olgu Sunumu
📍Scope:Comprehensive Sample
⚙️Variables:Post Covid-19 · Actinomycosis · Osteonecrosis

Abstract

Osteonecrosis can be seen in post-Covid-19 patients due to the damage to their immune systems and the medications they take. This case report deals with the diagnosis, treatment and follow-up of actinomycotic osteonecrosis of the maxilla, which is one of the very rare post-covid conditions. The medical history of the 48-year-old patient, who had received treatment for Covid-19 in the intensive care unit about 1 year ago and had no systemic disease, revealed left palatinal and buccal bone exposure, suppuration and oroantral relationship. After limiting the lesion with pentoxifylline and alpha tocopherol, all necrotic bone tissue was removed and the area was closed with Bichat fat pad. The removed tissue was sent for histopathologic and microbiologic examination. The area was closed primerally. Postoperative follow-up of 1 year was completed and no new lesion was observed. Microbiologic evaluation was positive for actinomyces. This case may shed light on clinicians to give importance to the follow-up of patients with Covid-19 and its variants, especially if they have a history of hospitalization, to provide a differential diagnosis for PC-RONJ even if the interval is long, and not to skip the microbiological evaluation stage.

Özet

Osteonecrosis can be seen in post-Covid-19 patients due to the damage to their immune systems and the medications they take. This case report deals with the diagnosis, treatment and follow-up of actinomycotic osteonecrosis of the maxilla, which is one of the very rare post-covid conditions. The medical history of the 48-year-old patient, who had received treatment for Covid-19 in the intensive care unit about 1 year ago and had no systemic disease, revealed left palatinal and buccal bone exposure, suppuration and oroantral relationship. After limiting the lesion with pentoxifylline and alpha tocopherol, all necrotic bone tissue was removed and the area was closed with Bichat fat pad. The removed tissue was sent for histopathologic and microbiologic examination. The area was closed primerally. Postoperative follow-up of 1 year was completed and no new lesion was observed. Microbiologic evaluation was positive for actinomyces. This case may shed light on clinicians to give importance to the follow-up of patients with Covid-19 and its variants, especially if they have a history of hospitalization, to provide a differential diagnosis for PC-RONJ even if the interval is long, and not to skip the microbiological evaluation stage.

🔖

Cite This Article

Altay, M. A., Eroğlu, C. N., Karaca, B., Doğan, S. U. (2025). Post-COVID-19 Extensive Maxillary Actinomycotic Osteonecrosis: A Rare Case Report. Akdeniz Diş Hekimliği Dergisi, Cilt: 4 Sayı: 1, 63–69. https://doi.org/10.62268/add.1652574

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