Journals / Ağrı Tıp Fakültesi Dergisi / 2026 / Cilt: 2 Sayı: 1

Predictability of Chronic and Persistent Lymphadenopathy in Childhood with Ultrasound and Laboratory Data: A Pediatric Hematology-Oncology Outpatient Clinic Experience

Çocukluk çağı Kronik ve Persistan Lenfadenopatilerin Ultrason ve Laboratuvar Veriler eşliğinde Öngörülebilirliği; Bir Çocuk Hematoloji-Onkoloji Polikliniği Deneyimi

Mehmet Ali Özel(DÜZCE ÜNİVERSİTESİ)0000-0001-8817-5769
Pages
24–31
Publication Date
2024-02-29
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Conclusion: In conclusion, it has been shown that in the presence of lymphadenopathy, elevated hemoglobin and platelets, together with the presence of hilar vascularity, may be predictive findings in the failure of the lymph node to disappear.

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: Lymphadenopathies occupy an important part of pediatric hematology-oncology practice.
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Key Findings & Data:More than 95 per cent of cases are known to be reactive, and infection-related.
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Conclusion & Impact:Conclusion: In conclusion, it has been shown that in the presence of lymphadenopathy, elevated hemoglobin and platelets, together with the presence of hilar vascularity, may be predictive findings in the failure of the lymph node to disappear.
🔬Design:Araştırma Makalesi
📍Scope:2022-2023 Verileri
⚙️Variables:lenfadenopati · ultrasonografi · hemoglobin

Abstract

Aim: Lymphadenopathies occupy an important part of pediatric hematology-oncology practice. More than 95 per cent of cases are known to be reactive, and infection-related. Lymphadenopathies are followed up at 1-3-6 month intervals, and the process requires ultrasound follow-up. Our study aimed to compare the persistent and non-persistent cases. Results: In our study, lymphadenopathy cases (n=93) admitted to our pediatric haematology-oncology outpatient clinic between 2022-2023 were examined and diagnosed; reactive lymph nodes (n=76)(81. 7%), infectious mononucleosis (n=9)(9. 7%), tuberculosis (n=1)(1%), lymphoma (n=2)(2%), benign cytology (n=2)(2%). Mean age ± standard deviation (SD); 8. 2±4. 4, number of girls; 42 (45. 2%). The median time to resolution of acute (n=8)(8. 6%), subacute (n=26)(28%), chronic (n=59)(63. 4%) lymphadenopathy was 1 [5-155] week. Cases with and without ultrasonographic disappearance of lymphadenopathy were compared; the mean hemoglobin value (g/dL) (12. 7±1. 4 vs. 12. 3±1. 2, respectively) (p=0. 047) and platelet value (x10³/mm³) (334. 2±108. 012 vs. 288. 4±89. 5, respectively) (p=0. 047) were higher and the presence of hilar vascularity on ultrasonography (76% vs. 98. 1%) (p=0. 001) was LOWER in those who disappeared compared to those who did not disappear. There was no correlation between hypoechoic lymph node, indistinct border, necrosis, fatty hilus, perinodal cortical vascularity, cortical thickening, presence of lymph node in more than one region and non-loss of lymph node. Conclusion: In conclusion, it has been shown that in the presence of lymphadenopathy, elevated hemoglobin and platelets, together with the presence of hilar vascularity, may be predictive findings in the failure of the lymph node to disappear. Key words: lymphadenopathy, ultrasonography, haemoglobin, platelets, childhood

Özet

Amaç: Lenfadenopatiler, çocuk hematoloji-onkoloji pratiğinin önemli bir kısmını işgal etmektedir. Yüzde 95'den fazla olgunun, reaktif, enfeksiyon ilişkili olduğu bilinmektedir. Lenfadenopatiler, 1-3-6 ay aralarla takip edilmektedir, ve süreç ultrason takibi gerektirmektedir. Çalışmamızın amacı, laboratuvar ve ultrason bulgularının lenf nodunun normal boyuta inmesini öngören faktörlerin araştırılmasıdır. Materyal-Metod: Çalışmamızda, 2022-2023 yılları arasında çocuk hematoloji-onkoloji polikliğimize başvuran lenfadenopati olgular (n=93) incelendi. Normal boyuta ulaşan ve ulaşmamış lenf nodlarının özellikleri karşılaştırıldı. Sonuçlar: Tanılar; reaktif lenf nodu (n=76)(%81,7), enfeksiyöz mononükleoz (n=9)(%9,7), tüberküloz (n=1)(%1), lenfoma (n=2)(%2), benign sitoloji (n=2)(%2) idi. Ortalama yaş ± standard sapma (SD); 8.2±4,4, kız sayısı; 42 (%45,2) idi. Akut (n=8)(%8.6), subakut (n=26)(%28), kronik (n=59)(%63,4) lenfadenopatinin ortanca kaybolma süresi 1 [5-155] hafta bulundu. Lenfadenopatinin ultrasonografik kaybolduğu ve kaybolmadığı olgular kıyaslandı; kaybolanlarda, kaybolmayanlara göre ortalama hemoglobin değeri (g/dL)(sırasıyla 12,7±1,4'e 12,3±1,2) (p=0,047) ve trombosit değeri (x10³/mm³) (sırasıyla 334.2±108.012'e 288.4±89.5)(p=0,047) daha yüksek, ultrasonografide hiler vaskülaritenin varlığı (%76'a %98,1)(p=0.001) daha DÜŞÜK oranda istatistiksel anlamlı bulundu. Hipoekoik lenf nodu, sınır belirsizliği, nekroz, yağlı hilus, perinodal kortikal vaskülarite, kortikal kalınlaşma, birden çok bölgede lenf nodu varlığının olması ile lenf nodunun kaybolmaması arasında bir ilişki gösterilemedi. Sonuç: lenfadenopati varlığında, hemoglobin ve trombosit yüksekliğinin ile hiler vaskülarite varlığı ile birlikte lenf nodunun kaybolmamasında öngörücü bulgular olabileceği gösterilmektedir.

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Cite This Article

Çakmak, H. M., Özel, M. A. (2024). Predictability of Chronic and Persistent Lymphadenopathy in Childhood with Ultrasound and Laboratory Data: A Pediatric Hematology-Oncology Outpatient Clinic Experience. Ağrı Tıp Fakültesi Dergisi, Cilt: 2 Sayı: 1, 24–31. https://doi.org/10.61845/agrimedical.1360375

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