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Journals / Ağrı Tıp Fakültesi Dergisi / 2024 / Cilt: 2 Sayı: 3

Metal Poisoning and Chelation Therapy

Metal Zehirlenmeleri ve Şelasyon Tedavisi

Pınar Buluz(Bozkır İlçe Milli Eğitim Müdürlüğü)0009-0007-9110-4428
Nuri Başpınar(SELÇUK ÜNİVERSİTESİ, VETERİNER FAKÜLTESİ)0000-0002-5481-1111
Pages
126–131
Publication Date
2024-10-30
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this review, we provide an update on available chelation agents and treatment strategies for the treatment of five heavy metal (mercury, lead, arsenic, cadmium, copper) intoxications.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Despite more than half a century of clinical experience, chelation for toxic heavy metals remains one of the most controversial and misapplied interventions in clinical toxicology.
📊
Key Findings & Data:There is sufficient evidence that the proper use of specific chelates, when combined with general supportive care, reduces the morbidity and mortality associated with serious poisonings.
💡
Conclusion & Impact:In this review, we provide an update on available chelation agents and treatment strategies for the treatment of five heavy metal (mercury, lead, arsenic, cadmium, copper) intoxications.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:metal · zehirlenme · civa

Abstract

Despite more than half a century of clinical experience, chelation for toxic heavy metals remains one of the most controversial and misapplied interventions in clinical toxicology. There is sufficient evidence that the proper use of specific chelates, when combined with general supportive care, reduces the morbidity and mortality associated with serious poisonings. In this review, we provide an update on available chelation agents and treatment strategies for the treatment of five heavy metal (mercury, lead, arsenic, cadmium, copper) intoxications.

Özet

Yarım yüzyıldan fazla süren klinik deneyime rağmen, toksik ağır metallere yönelik şelasyon, klinik toksikolojide en tartışmalı ve yanlış uygulanan müdahalelerden biridir. Spesifik şelatların doğru kullanımının genel destekleyici bakımla birleştirildiğinde ciddi zehirlenmelerle ilişkili morbidite ve mortaliteyi azalttığına dair yeterli kanıt vardır. Bu derlemede, beş ağır metal (civa, kurşun, arsenik, kadmiyum, bakır) intoksikasyonunun tedavisi için mevcut şelasyon ajanları ve tedavi stratejileri hakkında bir güncelleme sunuyoruz.

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Cite This Article

Buluz, P., Başpınar, N. (2024). Metal Poisoning and Chelation Therapy. Ağrı Tıp Fakültesi Dergisi, Cilt: 2 Sayı: 3, 126–131. https://doi.org/10.61845/agrimedical.1503465

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