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Journals / Kafkas Journal of Medical Sciences / 2018 / Cilt: 8 Sayı: 3

Retrospective Analysis of Nasopharynx Punch Biopsy Results

Nazofarenks Punch Biyopsi Sonuçlarının Retrospektif Analizi

Selçuk Güneş
Mustafa Çelik
Burak Olgun
İrem Özen
Hüseyin Avni Ulusoy
Pages
203–206
Publication Date
2018-12-01
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: Taking punch biopsies containing mucosa and submucosa will provide the early diagnosis and treatment of nasopharyngeal carcinoma, in spite of the absence of a mass on endoscopic examination.

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: Evaluation of nasopharyngeal punch biopsy results due to malignancy suspicion.
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Key Findings & Data:Material and Method: In total, 491 patients (231 females 260 males; average age 36.72± 16.91 years ; range 16 –90 years) were included in the present study.
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Conclusion & Impact:Conclusion: Taking punch biopsies containing mucosa and submucosa will provide the early diagnosis and treatment of nasopharyngeal carcinoma, in spite of the absence of a mass on endoscopic examination.
🔬Design:Araştırma Makalesi
📍Scope:Comprehensive Sample
⚙️Variables:nazofarenks · biyopsi · endoskopi

Abstract

Aim: Evaluation of nasopharyngeal punch biopsy results due to malignancy suspicion. Material and Method: In total, 491 patients (231 females 260 males; average age 36.72± 16.91 years ; range 16 –90 years) were included in the present study. All patients files were evaluated in terms of age, gender, the reason and the results of biopsy. Results: Nasopharyngeal carcinoma was diagnosed in 21 patients (4.2%) as a result of nasopharyngeal punch biopsies performed due to malignancy suspicion and exclusion. Results of pathological evaluation of other patients; 454 benign pathologies (lymphoid hyperplasia, chronic lymphoid process, Tornwald cyst) (92.05%), 12 insufficient material (2.44%) and 4 granulomatous diseases (0.8%), respectively. The mean age of patients with malignancy was statistically significantly higher than those with benign pathology (p = 0.000). There was no statistically significant difference in the gender distribution of malignant and benign cases (p = 0.077). Conclusion: Taking punch biopsies containing mucosa and submucosa will provide the early diagnosis and treatment of nasopharyngeal carcinoma, in spite of the absence of a mass on endoscopic examination.

Özet

Amaç: Malignite şüphesi nedeniyle yapılan nazofarenks punch biyopsi sonuçlarının değerlendirilmesi. Materyal ve Metod: Çalışmaya toplam 491 olgu (231 kadın 260 erkek; ortalama yaş 36.72±16.91 yıl, aralık 16-90 yıl) dahil edildi. Tüm olguların dosyaları, yaş, cinsiyet, biyopsi yapılma nedeni ve biyopsi sonuçları açısından retrospektif olarak değerlendirildi. Bulgular: Malignite şüphesi olan ve ayırıcı tanı amacıyla nazofarenks punch biyopsisi yapılan hastalardan 21’i (%4.2) nazofarenks karsinomu tanısı almıştır. Diğer olguların patolojik değerlendirme sonuçları; 454 benign patoloji (lenfoid hiperplazi, kronik lenfoid süreç, (Tornwald kisti) (%92.46), 12 yetersiz materyal (%2.44) ve 4 granülamatöz hastalık (%0.8) olarak saptanmıştır. Malignite saptanan olguların ortalama yaşları, patoloji sonucu benign olan olgulara göre istatistiksel olarak anlamlı düzeyde daha yüksektir (p=0.000). Malign ve benign olguların cinsiyet dağılımında istatistiksel olarak anlamlı farklılık saptanmamıştır.   Sonuç: Nazofarenks kanseri şüphesinde, endoskopik muayenede yer kaplayıcı kitle olmasa da mukoza ve submukozayı içeren punch biyopsi uygulaması nazofarenks kanserinin erken tanı ve tedavisine imkan sağlayacaktır.

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Cite This Article

Güneş, S., Çelik, M., Olgun, B., Özen, İ., Ulusoy, H. A. (2018). Retrospective Analysis of Nasopharynx Punch Biopsy Results. Kafkas Journal of Medical Sciences, Cilt: 8 Sayı: 3, 203–206. https://ajindex.com/articles/1631869

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