Journals / Çocuk Acil ve Yoğun Bakım Dergisi / 2015 / Cilt: 2 - Sayı: 1

Meningococemia in Pediatric Intensive Care Units:Demographic, Epidemiological and Clinical Features

Çocuk Yoğun Bakım Ünitelerinde Meningokoksemi: Demografik, Epidemiyolojik ve Klinik Özellikler

Pages
7–11
DOI
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⚡ TL;DR(Too Long; Didn't Read)

The mean length of PICU stay was 6 days (1 to 29 days) and the overall mortality rate was 21% (7 patients).

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: The aim of this study was to review demographic, epidemiological, clinical, and laboratory characteristics of meningococcemia patients in pediatric intensive care units (PICU).
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Key Findings & Data:Methods: Investigators from 4 dierent PICUs reviewed the medical records of children aged between 1 month to 18 years and diagnosed with meningococcemia with or without meningitis.
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Conclusion & Impact:The mean length of PICU stay was 6 days (1 to 29 days) and the overall mortality rate was 21% (7 patients).
🔬Design:Review & Systematic Survey
📍Scope:2015 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: The aim of this study was to review demographic, epidemiological, clinical, and laboratory characteristics of meningococcemia patients in pediatric intensive care units (PICU). Methods: Investigators from 4 dierent PICUs reviewed the medical records of children aged between 1 month to 18 years and diagnosed with meningococcemia with or without meningitis. Results: There were a total of 33 patients in the study period. The median age at admission was 3,4±2.1 years. In all, 22 (67%) were male. Fever was the rst symptom in 84% of the patients and 97% of them had meningococcemic rashes at admission. Lumbar puncture was performed to 45% of the patients and 7 (21%) of them had meningitis with meningococcemia. N. meningitidis was cultured from 7 blood and 2 cerebrospinal uid samples. An average of 60 mL/kg uid bolus was given to 93% of the patients within the rst hour of hospital admission. Dopamine, dobutamine, and epinephrine were given to patients who required inotropic and vasopressor infusions (54.5%, 27.2%, 12.1% of the patients,respectively). Fifty-eight percent of the patients received steroid therapy and 12% of them received heparin infusion for disseminated intravascular coagulation and purpura fulminans. The mean length of PICU stay was 6 days (1 to 29 days) and the overall mortality rate was 21% (7 patients). Conclusion: Although demographic, epidemiological, clinical, and laboratory characteristics of our patients were similar to previous reports, mortality rate was higher CAYD 2015;2(1):7-12.

Özet

Amaç: Meningokoksemi tanısıyla çocuk yoğun bakım ünitelerinde (ÇYBÜ) izlenen hastaları demograk, epidemiyolojik, klinik ve laboratuvar özellikleri açısından değerlendirmektir. Yöntemler: Dört farklı ÇYBÜ'de takip ve tedavisi yapılan, menenjitin eşlik ettiği veya tek başına meningokosemi tanısı almış 1 ay-18 yaş arası çocukların tıbbi kayıtları değerlendirildi. Bulgular: Çalışmaya toplam 33 hasta dahil edildi ve ortalama yaş 3.4±2.1 yıldı. Hastaların 22 (%67)'si erkekti. Hastaların %84'ünde ateş ilk semptomdu ve %97'sinde tanı anında meningokoksemiye ait döküntü saptandı. Lomber ponksiyon hastaların %45'ine yapıldı ve 7 (%21)'sinde eşlik eden menenjit olduğu görüldü. N. meningitidis 7 hastanın kan kültüründe ve 2 hastanın BOS kültüründe üretilebildi. Hastaların %93'ü hastaneye başvurduktan sonraki ilk 1 saat içerisinde ortalama 60 ml/kg sıvı bolusu aldı. İnotropik ve vazopressör tedavi olarak 18 (%54.5) hastaya dopamin, 9 (%27.2) hastaya dobutamin ve 4 hastaya (%12.1) epinefrin infüzyonu verildi. Hastaların %58'inde steroid, %12'sine ise dissemine intravasküler koagülasyon ve purpura fulminans nedeniyle heparin infüzyonu uygulandı. Ortalama yoğun bakım yatış süresi süresi 6 gün (1-29 gün), mortalite oranı %21'di. Sonuç: Çalışmamızdaki hastaların demograk, epidemiyolojik, klinik ve laboratuvar özellikleri daha önce yapılan çalış- malarla benzer olmakla birlikte, mortalite oranı yüksek olarak bulunmuşturCAYD 2015;2(1):7-12.

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Cite This Article

KENDİRLİ, T., YILDIZDAŞ, R. D., BOŞNAK, M., KÖROĞLU, T., DUMAN, M., TEKİN, D., YILMAZ, H. L., ÇELİK, Ü., ÖDEK, Ç., İNCE, E., KARABÖCÜOĞLU, M. (2015). Meningococemia in Pediatric Intensive Care Units:Demographic, Epidemiological and Clinical Features. Çocuk Acil ve Yoğun Bakım Dergisi, Cilt: 2 - Sayı: 1, 7–11. https://ajindex.com/articles/162319

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